Speaking, the power of stimulating innovation creates a feast of the development of national life and technology development

The power of excitement and innovation creates a feast of the development of national life and technology development

——The Fifth Innovation Driven Development Conference and 2022 China Baishishan Life Science Conference Speech Report Speech

Editor

Innovate driving development and develop inclusive people's livelihood. On July 16th, with a strong mission, he visited the Fifth Innovation Driven Development Conference and the 15 Academician experts at the 2022 China Baishishan Life Sciences Conference to share the cutting -edge viewpoints, stimulate the power of technology, and explore new questions in the form of aimed at the main purpose report. , Copy a high -end dialogue platform for life science and biomedical health industries, seek the construction of national regional medical centers and international medical bases, build Jingxiong's international life health corridor, and join hands to promote the development of Baoding and even the national life and health industry.

Traditional Chinese medicine is traditional medicine, and it is also future medicine

Master Li Yangui Chinese Medical Medicine, Professor and Chief Physician of Hebei Provincial Hospital of Traditional Chinese Medicine

"In the future, the research direction of medicine should not continue to take diseases as the main research field, but should take human health as the main research direction of medicine." Li Yigui pointed out that in the final analysis, this is the classic Chinese medicine classic "Yellow Emperor's Cannon in the Yellow Emperor's Canon more than 2,000 years ago in my country. "The three words mentioned" Treatment of disease ". He pointed out that traditional Chinese medicine is the treasure of the country. Traditional Chinese medicine has spread to more than 180 countries and regions. TCM acupuncture has been included in the "Human Intangible Cultural Heritage List". Classification code. Furthermore, the long history of Chinese medicine proves its brilliant achievements and deep heritage, but it definitely does not mean that it is an old and outdated theory. On the contrary, some of its ideas are still advanced. The "Yellow Emperor's Canon" once said that "the cure has not been cured, and the cure has not been chaotic." The idea of ​​"treating the disease without disease" of Chinese medicine will lead the new direction of future medical development. On this basis, he proposed the "turbid poisoning theory", which referred to the "turbid poison" that is harmful to the human body and bad mental stimuli. The turbid poison of heaven includes air pollution, noise, electromagnetic radiation, light radiation, etc., and the turbid poison of the ground includes contaminated soil and ocean, food, polluted diet, and daily chemicals abuse. Not smooth, diet, bad habits, metabolic diseases, etc. The human body produces turbid poison. These are both the pathogenic factor and disease. He proposed a new outlook on disease, namely turbidity; the new outlook on quality, that is, turbidity; the new outlook on health, that is, to remove the three major turbid poisons, care for the outside of the earth, purify the inner environment of the human body, so as to make the human body clean and bright.

Invention and discovery dialectical relationships on promoting scientific progress

Academician Zhang Yingze China Academy of Engineering, Dean of the Institute of Orthopedics and Innovation Technology, Hebei Province

"Discovery is science, cannot be innovated, and cannot be declared patent; invention is technology, must be continuously innovated, and must be declared patent." In the main report, Zhang Yingze opened the "discovery", "invention" for the classic cases from ancient times to the present. "New ideas of this set of keywords. It is found that the first cognition and summary of the objective existence and objective laws of the birth and death, development, and cycle of nature is found; invention is first created in accordance with the objective laws. For example, Chinese medicine has a blind medicine called Yin Chen. As early as 1700 years ago, the working people of our country found that all mosquitoes were long in all grass. it is good. It was then found that there was still a mosquito in the dry Artemisia annua, and the artemisiah was cut off. Later, the Eastern Jin Gehong's "Elbow Ready Prescription" recorded that "drinking artemisiacis can cure malaria". After unremitting efforts and scientific research, Professor Tu Yu finally won the "Chinese medicine medicine" that benefited hundreds of millions of people around the world. In the process of promoting the development of natural science in my country, we must pay attention to the original discovery of this "source of living water", dare to discover, have the spirit of questioning, have the courage to break the inherent thinking, and also have the courage and patience of tracing the source. Only this is this. In order to see the essence through the phenomenon and reveal the inherent laws of things. In the end, Academician Zhang Yingze pointed out that the invention and discovery have created the road of natural science. If natural science is compared to a clear and deep river, then scientific discovery is the source of never exhausting, and technology inventions are the lakes of the Star Rome.

The relationship between artificial intelligence and big data and pharmaceutical research

Academician of Cong Bin China Academy of Engineering, vice chairman of the Central Committee of the Jiu San Society, Professor of Hebei Medical University

In the main report of the day, Cong Bin believes that today's world technology is on the eve of major changes. The original scientific research paradigm can no longer achieve the substantial breakthrough of scientific theory, and even the theoretical conflicts are often. Therefore, the scientific research paradigm needs profound changes. To this end, he started from the cognition and transformation of a scientific research paradigm and explained in detail the 4 paradigms of experimental science, theoretical science, computer science, and data densely driving, and focused on the importance of the data dense driving paradigm. He believes that the portrayal of data is sometimes space -free, while humans need different information, and the carrier is data. Data driver is to use various advanced technologies to extract information from the changes of time and space nodes, and to obtain awareness of the development of things after logical processing. He believes that the three major tasks in life science can be completed through the research of artificial intelligence and big data: the first is to discover the structure, the second is to discover the relationship between the structure and the structure, and the third is to find the structure between the structure and the structure Dynamic development rules. He believes that through computer simulation, push through data, and through AI learning and analysis, there may be new discoveries. He summarized the research in the field of life sciences into three major subject issues: analyzing the micro -structure of the life body, the association relationship between the exploration structure, and revealing the timing change law of the structure and functions. Faced with the complex network representation of multiple groups, multi -scale, multi -scale, cross -space, and cross -level interactions of life and health, he believes that it is possible to reveal Human energy information network complex giant system. Five major element innovations in hospital construction in the future

Meng Jianmin China Academy of Engineering and chief chief architect of Shenzhen Architectural Design and Research Institute

"Summarizing the construction experience of Shenzhen Hospital, I think the construction of Chinese hospitals should be innovated in the five major elements in the future. These are the core contents of the hospital design." Essence Modern hospitals have two characteristics: complexity and dynamic characteristics: complexity refers to its multi -disciplinary integration and cross -characteristics, including complex disciplines, professional complexity, and complex procedures; dynamicity refers to the hospital in dynamic development and changes, including knowledge, including knowledge Iteration, technology iteration and operation and iteration are mainly based on two aspects of standards, the development of medical models, and changes in human -oriented needs. At present, the medical model is gradually evolving from simple treatment to emphasizing treatment and prevention. Accordingly, the development of Chinese hospitals can be summarized as four stages: traditional, high -efficiency, ecological, and smart. Summarizing some experience in the construction of Shenzhen Hospital, he believes that the construction of hospitals should be innovated in the following 5 aspects, that is, the resource organization adopts the "systemic" sharing model; the traffic organization adopts the "interoperability" hub model; the logistics logistics adopts the "warehousing" "storage type" Delivery mode; energy consumption operation and maintenance adopts "ecological" energy -saving mode; smart hospitals adopt "big data" drive mode. Only when you stand at a higher dimension, think more about the whole process design, and through the multi -dimensional knowledge coordination system through the system, through multi -disciplinary cross -creative creative methods in cross -border, can you keep up with the implementation path through diverse openness in innovation, can you keep up with the times? Demand, better service.

Shouzheng innovation, leading demonstration, and creating a new pattern of high -quality development in the Hospital of Traditional Chinese Medicine

Wang Xiaotong's Party Committee Secretary of the Guang'anmen Hospital of China College of Traditional Chinese Medicine

Shouzheng and innovation are the eternal theme of the development of traditional Chinese medicine, and it is also the era of the era of high -quality development of public traditional Chinese medicine hospitals. In the main report of the day, Wang Xiaotong introduced the annual outpatient volume of Guang'anmen Hospital 3.5 million, and the current status of the first place in Beijing TCM medical institutions. At the same time, she also described the three major aspects of the high -quality policy background, practical exploration, and thinking of the high -quality development of traditional Chinese medicine hospitals. In terms of policy background, she explained the current status of the National Traditional Chinese Medicine Hospital with detailed data: 5715 Chinese medicine hospitals, 1.197 million beds, 690 million diagnosis and treatment, and 31.52 million discharge ... Configuration, strengthen scientific management, and achieve high -quality development. In the report, with the development of Guang'anmen Hospital, she demonstrated the requirements and construction directions of the high -quality development of traditional Chinese medicine hospitals: to cultivate famous doctors, build famous sciences, famous medicines, and create a famous hospital; to build mechanisms, promote management, and strengthen Teams, paid fire; On April 29 this year, it covers an area of ​​166.7 acres, with a construction area of ​​262,000 square meters. The design beds were designed with 100 beds and a total investment of 3.138 billion yuan. 27 functional offices, 39 clinical departments, 20 medical technical departments, and 3 research platforms. The focus is on oncology, cardiovascular, endocrinology, dermatology, anorectal, gynecology, spleen and stomach disease, etc. At the same time, she also hoped that at the same time, she also hoped that on the basis of establishing and improving the management system of modern hospitals, she strengthened the leadership of party building and condensed to build a "highland" of traditional Chinese medicine services in the national regional medical center.

The strengths of Chinese and Western medicine are concentrated.

Yao Xixian Master of Chinese Medicine, Professor of the Second Hospital of Hebei Medical University

"Chinese medicine can be treated with poor treatment of western medicine, but the same is true, so there are each director." To this end, Yao Xixian advocates the long -term differences in Chinese and Western medicine in academic ideas. Cases explain equal emphasis on Chinese and Western medicine. "The condition of chronic hepatitis B can be controlled by Western medicine, but the hepatitis B sclerosis is powerless. In this case, the use of blood circulation stasis, astragalus, turmeric, and western red flowers have a good effect. The treatment effect of syndrome differentiation will be very good. "At the forum conference, he also shared the rich experience and unique insights of chronic gastritis and chronic kidney disease in clinical treatment. He proposed to pay attention to modern medical progress in clinical treatment, emphasize the combination of "discerning disease" and "syndrome differentiation", and adopts flexible treatment methods for different "diseases" and corresponding "syndrome". Actively explore new ideas and methods. For decades, he has devoted herself to the combination of Chinese and Western medicine to study the study, has a high reputation in liver disease, and has unique insights in chronic gastrointestinal disease, chronic liver disease and digestive acute acute acute acutes. The many cases he listed in the report are enough to illustrate the value of the combination of Chinese and Western medicine in clinical applications. The role of traditional Chinese and Western medicine, the combination of traditional Chinese and Western medicine can be imagined. "I advocate the combination of Chinese and Western medicine, and is willing to add bricks to improve the Chinese medical system." He said. The strong road to modern power is inseparable from the implementation of the big scientific plan

He Fuchu Academician of the Chinese Academy of Sciences and researcher at the School of Military Sciences

The achievement of the large scientific plan and consolidation of the status of a strong science and technology country. At the historical stage of "strengthening" in China, He Fuchu used the Manhattan plan, the human genome plan, and the Apollo plan as an example to tell the long -term impact of the large scientific plan on the United States, and then quoted the large scientific plan in the field of bioscience. With the launch of China's leading human protein group plan, it is not only large -scale in Chinese history, but also unprecedented in the history of protein groups in the world. Promote such a large plan to have corresponding large scientific facilities. With the support of the National Development and Reform Commission, the construction of the "Phoenix Project" platform is completed. The "Phoenix Engineering" platform has a significant radiation effect and rich social benefits. This major platform has attracted a group of internationally renowned experts including Shi Yigong to return to China. The technical support for 6 experts has been elected academicians, serving more than 400 units in more than 42 countries around the world. He believes that "the country's heavy weapon" has produced a significant supporting role in China's development science development, the attraction and production of China's biological industry and the recovery of China's top talents. He also hopes to use basic results for future tumor diagnosis and treatment, thereby promoting my country to enter the era of precision medicine driven by protein groups. At present, the Ministry of Science and Technology is advancing and cultivating a large scientific plan that can lead the global nature. Among them, the human protein group plans to be settled in Guangzhou, the "Huyan" international headquarters plan, and is currently being implemented.

The physical essence of ultra -low energy consumption of life

Academician of Jianglei Chinese Academy of Sciences, Researcher of the Institute of Chemistry, Chinese Academy of Sciences

In the keynote report, Jiang Lei faced the ultimate scientific issue of life science and medicine -how does life achieve high -low energy consumption efficient information transmission, energy conversion, and material cooperation? Human brain intakes 2,000 kcal per day, 20 watts of power, 600 volt of electric eel discharge, chicks can hatch out 21 days under 38 degrees Celsius ... Electric eel discharge can reach 600 volts, why not burn yourself into baking fish? It is because of the ions with ultra -low impedance ion group movement. Superconducting is the ultra -low impedance transportation of electronics. Low temperature causes the lattice to shrink. The electrons on the adjacent atomic potential energy curve generate gravitational gravity, forming "Cooper Electronics". Ultra -guided state is the same frequency of "Cooper Electronics" in the same frequency. Resonance macro quantum. Atomic ultra -low impedance transportation status, zero viscosity (no Brown movement), no kinetic energy loss during collective transportation. The movement of hundreds of millions of myocardial cells drives the heart beating. The pulse of myocardial cells is the performance of typical life information storage and output. Programming. The lung muscle cells also have the information storage/output function of gene programming and central nervous system regulation. The pulmonary muscle cells can be controlled by the central nervous system. Humans have two gene -programming information storage. The first is natural, such as heart beating and breathing. The day after tomorrow is shallow programming, it takes time to learn and turn it into deep programming. Such as writing, painting, and playing table tennis. Jiang Lei believes that the answer to the ultimate question of life sciences is that ultra -low -resistant material transportation is a necessary condition for achieving these processes.

Model pig's large -scale creation and life medical innovation

Meng Anming Academician of the Chinese Academy of Sciences, professor at Tsinghua University

Animal model is an important tool for studying human development and diseases, as well as determining effective treatment methods and vaccines. With the rapid development of genomics and protein group studies, the status of various experimental animals in the field of biomedical research is undergoing drama. In the main report of the day, Meng Anming first began to explain the limitations of traditional model animals such as nematodes, fruit flies, zebrafish, mice. He said that compared with traditional models, pigs are very similar to humans regardless of organizational or organ forms, physiological regulatory methods, behavioral patterns and genetic regulation mechanisms. They are currently recognized cardiovascular diseases, metabolic diseases and metabolic diseases and Important model of organ transplantation research. As a large -scale model animal, pigs also have attribute advantages such as convenient breeding, short fertility time, multi -producing childbirth and genomic and easy -to -edit. It is a new way to break through the bottlenecks of animal research. In the report, he pointed out that pig works are human biomedical models and have the most obvious role in 13 key areas such as eye science, skin research, heart disease, lung disease, diabetes, cancer, and alien organ transplantation. In addition, in the treatment of islet cell transplantation for diabetes, nerve cell transplantation, Parkinson, red blood cell transplantation provides blood and eyeballs to provide cornea, etc. Pigs will lead the biomedical revolution. He said that my country has the advantages of model pig varieties and has mastered pig -based genetic mutation technology. At present, it is promoting the "Model Animal Panel and Genetic Research" project in Baoding Prefecture. Enhance international competitiveness. Realize the new model of oral health creation of system health prevention and control

Academician of Wang Songling Chinese Academy of Sciences and Vice President of Capital Medical University

"Cover from the mouth, oral health is essential for whole body health." In the keynote report, Wang Songling pointed out that maintaining oral health is a necessary condition to achieve systemic health. You can use periodontitis regeneration, dental development, biological dental root regeneration, and regeneration of biological dental roots, and regeneration of biological dental roots. Nitrate treatment and protection of slow diseases. Dental health is the cornerstone of oral health. New drugs for dental pulp are provided with new models for periodontitis. After the treatment of periodontitis in the portic and stem cells, the teeth and swelling disappear, the periodontal pockets are significantly reduced, and the alveolar bone regeneration is significant. Lack of teeth is an important factor affecting the quality of human life. Mechanical replacement treatment cannot fully achieve physiological repair. Biological dental root regeneration can achieve biological repair. The stem cell composite biological stent materials and stem cell membrane tablets are planted in the body, and regeneration of biological dentition with excellent biomechanics and biomechanical characteristics. The successful regeneration of the jaw bone is permanently displayed by the National Dental Museum and the International Museum of Stomatology. Biological dental roots are expected to become a new method for dental restoration. At the same time, nitrate is closely related to the health of the whole body. In stress, nitrate can increase the blood flow of mucosa and have a significant gastrointestinal protection effect; it can improve local blood flow in the parotid glands, prevent salivary gland radiation damage, and protect saliva secretion; Liver aging, protect the liver synthesis and decomposition metabolic function; improve the intestinal micro ecology and reduce the high -fat diet to induce obesity. In short, the application of nitrate preparations or drug prevention and treatment of systemic diseases has important application prospects.

Decrypting organs help precision medical treatment

Academician Chen Yiguang Chinese Academy of Sciences and professor of Tsinghua University

In the theme report of "Application of Organs in the Pharmaceutical Industry", Chen Yiguang scored multiple knowledge points on the research and development and application of relevant organ technology. In 2019, about 4 million people in my country have been diagnosed with cancer, and more than 10,000 people have been diagnosed a day on average. On the one hand, the incidence of cancer and mortality continued to increase, and on the other hand, the development of new drugs, high cost, high failure rate, and high risk. The application of organs solves the bottleneck of new drug research and development. The organs are a micro organ that has a three -dimensional structure cultivated in vitro. It has a complex structure similar to real organs and can partially simulates the physiological functions of the source tissue organs. It has great potential for application in disease treatment and drug development. The organs have established a disease model close to people, which is more advantageous than traditional biological specimens. Scientists can greatly reduce the cost and time of new drug research and development, and solve the bottleneck problem of new drug research and development. He explained that the huge potential of organs in the field of regeneration medicine are reflected in the use of gene editing technology to correct the genetic abnormalities in the body and return the healthy genetically modified cells back to the patient's body again, and integrate into the tissue in the later stage. Taking the treatment of tumor patients as an example, many medicines are now relatively common, but in fact, the condition that tumors occur on each patient are different. In this regard, organs can help very busy. Can find the medicine suitable for him or her, to achieve personalized treatment, which will help treatment greater help.

Wearable devices, artificial intelligence to help cardiovascular and cerebrovascular disease prevention

Academician Gu Dongfeng Chinese Academy of Sciences and Acting Vice President of the University of Science and Technology of China

In the main report of the day, Gu Dongfeng explained the current status and trend of the world's cardiovascular disease epidemic: In 2019 alone, cardiovascular disease caused 18.56 million deaths worldwide, of which my country reached 4.58 million. According to the development trend, between 2010 and 2030, due to the aging of the population and the growth of the population, the growth of coronary heart disease and stroke will exceed 50%, and the prevention and control of cardiovascular disease in my country is urgent. From 2013-2018, the mortality rate of cardiovascular and cerebrovascularization of the crowd in my country has declined significantly, and the life expectancy of residents' expectations will increase by about 1.38 years, indicating that the prevention and control of cardiovascular disease can significantly improve the life expectancy of Chinese residents. In the first -level prevention practice of cardiovascular and cerebrovascular diseases, he emphasized the comprehensive intervention and early prevention of various lifestyles, 7 of which were very important for cardiovascular health indicators: 4 behavioral factors (no smoking, controlling weight, increasing physical activity, increasing physical activity , Reasonable diet) and three physiological and biochemical factors (blood pressure, total cholesterol, and an empty blood glucose level reached the ideal level). He pointed out that if all 7 ideal health states are reached, adults in my country can reduce about 60%of cardiovascular disease. Based on intelligent wearable devices, he believes that wearable devices such as multifunctional watches and wrist blood pressure meters can realize the long -term dynamic monitoring of individual cardiovascular health indicators and promote the transformation of the disease management model. Or regular monitoring of life signs to facilitate the early screening or early warning of the disease. Artificial intelligence quickly process a large amount of medical data, greatly saving time, standardized processing, and good recurability. Different medical institutions are comparable, so as to maximize the liberation of doctors. Innovate the new model of cross -regional cooperation to help Beijing -Tianjin -Hebei Medical Cooperation Development

Zhao Chengsong Capital Medical University Deputy Dean of Beijing Children's Hospital

"Grasp the opportunity to solve the difficulties and the innovation system can develop coordinated." In the main report, Zhao Chengsong pointed out that it is necessary to innovate a new model of cross -regional cooperation and help Beijing -Tianjin -Hebei Medical Cooperation. In order to achieve the optimization of resource efficiency, improve service efficiency, expand service radius, and truly sink high -quality resources, Beijing Children's Hospital Innovation and Cross -regional cooperation is innovative and cross -regional cooperation. In 2014, the coordinated development of Beijing -Tianjin -Hebei was promoted to the national strategy; in 2015, Beijing Children's Hospital custody Baoding Children's Hospital to increase the "Beijing Children's Hospital Baoding Hospital"; use. The Baoding Hospital and Beijing Children's Hospital implements the same director, consistent diagnosis and treatment specifications, unified allocated resources, and horizontal homogeneity. , "One -to -one" teaching, "hand -to -hand" guidance, "incubation internal training" of local talents, science and education collaboration, building platforms, etc. to achieve deep integration, refine the professional settings of Baoding Hospital, fill the discipline gaps, and 13 disciplines have obtained it. The key discipline of Baoding Municipal Medical -level Medicine has ended the history of no discipline division in Baoding Children's Hospital. At present, more than 350 new diseases were added to Baoding Hospital in Beijing Children's Hospital, breaking through 169 new technologies and new projects, which helped the Baoding Hospital to improve the comprehensive service capacity building, realize the expansion of medical, teaching, research and prevention, and high -quality medical resources. Discovering Beijing's non -capital functions, gradually realizing serious illnesses.

Supplement folic acid to reduce blood pressure to prevent stroke

Director and Professor of Heart Department and Heart Center of the First Hospital of Huo Yong Peking University

Stroke is one of the world's recognized diseases that seriously threatened human health. The first cause of death of the Chinese was the first in the world. Huo Yong pointed out in the report of "Chinese Stroke: Innovation Theory and Innovation Practice" that the treatment of antihypertensive treatment is particularly important for prevention of stroke. Stroke, also known as "stroke" and "cerebrovascular accident", is an acute cerebrovascular disease. He pointed out that in terms of traditional risk factors, the most important thing is related to hypertension. Hypertension is the first pathogenic factor in stroke. In the report, he proposed the "H -type hypertension theory" and proposed that by supplement folic acid, it can prevent stroke. "More than 20 years ago, we did a lot of epidemiological surveys and surveyed a phenomenon. Among the hypertension patients in China, there was a substance called same cysteine ​​(HCY). Called H -type hypertension, three -quarters of Chinese hypertension patients are H -type hypertension. "He said that supplementing folic acid and reducing same type of cysteine ​​can reduce stroke. Confirm that supplementing folic acid can reduce stroke. How to screen H -shaped hypertension in practice, precise prevention and control, and effectively control the onset of stroke? In the process, new drug research and development and diagnostic kits were promoted. "As long as everyone can generally transform and promote scientific research results. In one area, it will decrease by 20.1%within five years, and it can reduce the occurrence of strokes of more than 1 million nationwide." Huo Yong said.

New strategy of targeted treatment of inner ear disease

Yang Shiming Director and Professor of the Ministry of Ling, Throat and Neck Surgery of the General Hospital of the People's Liberation Army

"The Department of otolaryngology was originally called a facial features, which is not as fatal as cardiovascular and cerebrovascular diseases, but its incidence is very high and has a wide range of nature." Yang Shiming went straight into the theme in the main report, and explained it through a series of examples. Requires the discipline difficulties and related technical research points of the OK. Internal ear disease is currently very difficult to treat, and the current method is to have cochlea. After processing the sound through computer technology, it is directly transmitted to the nerves. Although this breakthrough is effective, the penetration is relatively large. The key is to break through the inner ear barrier. For example, the first barrier -the blood -brain barrier, the whole body is administered. The blood vessel distribution in the ears is only as thin as the hair. If you give 10 ml medicine, only 0.1 ml enters the inner ear, you can imagine its effectiveness. The team worked hard to find the "target" in the inner ear, and then targeted the receptor. "After such a study, the tight internal ear barrier that the world has always wanted to open has been opened by us." Yang Shiming shared that this barrier can now produce strategies for tinnitus, deafness, and dizziness. Very small role. Through the combination of receptors and targets, we connected each medicine and set into the inner ear through the target setting, which changed our strategy for the entire ear therapy. Source ｜ Baoding Daily

Edit ｜ Lili

School pair ｜ Ai Chen

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