Chronic atrophic gastritis, relieve symptoms, reduce the risk of deterioration, what to pay attention to when taking medicine

Some friends asked Hua Zi, how can chronic atrophic gastritis treat, can it be cured, and how long should the medicine take? Hua Zi answered that chronic atrophic gastritis (CAG) is a difficult disease. The World Health Organization (WHO) lists it as a pre -cancer state. The disease is slow, and the condition will often be delayed.

Chronic atrophic gastritis can cause repeated damage to gastric mucosa epithelium, leading to a reduction in the inherent glands, and may be accompanied by a chronic gastric disease with intestinal epithelial or unprecedented disease proliferation. At present, chronic atrophic gastritis lacks effective therapeutic drugs. In terms of treatment, it is mainly used for individual medication for symptoms to alleviate symptoms and delay lesion progress and reduce the risk of cancer.

1. Clear Helicobacter pylori (HP)

Helicobacter pylori infection is the most common cause of chronic atrophic gastritis. After infection of H. pylori, it will cause long -term inflammatory stimulation to gastric mucosa, inducing immune reactions, which will lead to gastric mucosal atrophy and intestinal epithelium in some patients.

People with chronic atrophic gastritis, if they are accompanied by Helicobacter pylori infection, need to be cleared in time. In the "Fifth National Helicobacter Pyrobacteria Infection Hyb usage Report", it is believed that the elimination of Helicobacter pylori can eliminate inflammation reactions, slow down or terminate atrophy progress, and may even reverse atrophy.

my country's existing method of removing Helicobacter pylori in China is mainly "four -combined therapy", that is, a combination of 1 type of proton pump inhibitor, 1 types of pump, 2 types of antibiotics, and two antibiotics, which forms 4 drugs. Essence The removal rate of the "Four Records" is about 60%to 70%. If the removal fails, it should be replaced at least 3 months apart for other antibiotics and treated again.

Now it is also about the research of the "binary therapy" of Helicobacter pylori. The treatment ideas are to choose a proton pump inhibitor and 1 antibiotic, form two drug combination solutions, and take 14 days. Increasing the effect of the drug frequency can achieve the same effect as the "four -reciprocal therapy", but the adverse reactions are smaller and the cost is lower.

What kind of method and drugs are selected for the specific use of doctors.

Second, symptomatic treatment of different symptoms

Patients with chronic atrophic gastritis, clinical symptoms are not exactly the same. It is necessary to perform individualized medication according to different symptoms and treat symptomatic treatment.

1. Symptoms of gastric mucosa erosion, upper abdominal pain, upper abdomen burning sensation: You need to use gastric mucosa protective agents, such as aluminum carbonate, sulfur and aluminum aluminum and other drugs that can cover the protective effect of mucous membranes, can also adsorb bile, treat bile bile Gastric mucosal injury caused by reflux.

Anticurning agent needs to be used to reduce the damage to gastric mucosa in gastric acid. Although sodium bicarbonate, aluminum hydroxide and other direct neutralization of gastric acid, although it takes effect quickly, it lasts short. Therefore, the commonly used proton pump inhibitors ("Lazole" drugs), enabling the pH value> 4 in the stomach to reach 18 hours. You can also use H2 receptor inhibitors ("" Etin Datura ") to enable the pH value> 4 in the stomach to reach 8 hours.

2. There are indigestion symptoms such as upper abdomen, nausea, and vomiting: You need to use gastric dynamic drugs, and commonly used are drugs such as Dorazone, Moshairi, and Ito Billy. However, Panlone is rare, which can cause adverse reactions that cause severe arrhythmia, so the latter two types of gastric power drugs are more commonly used.

3. Symptoms such as abdominal distension, decreased appetite, decreased appetite during eating: need to use digestive enzymes, such as pancreatase enteric capsule, rice ibulin pancreatase, compound digestive enzyme, compound Azide mate and other drugs, which can enhance digestive enzymes Activation and promoting digestive function.

4. Symptoms of digestive tract accompanied by anxiety and depression: Long -term anxiety and depression can cause digestive tract symptoms, and long -term physical discomfort can induce anxiety and depression. Therefore, when the symptomatic treatment drug is not effective, you can try to find a psychologist for treatment. Under the guidance of a doctor, you can choose anti -anxiety drugs and anti -depression drugs. It may have unexpected results.

To sum up, the treatment of chronic atrophic gastritis is mainly to relieve symptoms and reduce the risk of cancer. Pymobacter pylori infection must be cleared in time. For symptomatic treatment according to different symptoms, the effect can be visible for about 4 weeks. It is not recommended to use gastric acid secretion drugs for a long time, and drugs can be discontinued after the symptoms are relieved. Drugs need to be used under the guidance of a doctor, and have doubts about medication, please consult a doctor or pharmacist. I am a pharmacist, and welcome to follow me and share more health knowledge.

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