8 weeks against age?"Non -Old Medicine" NMN Latest Clinical: Improve sugar and fat metabolism, cannot improve NAD+?
Author:Nutritionplus Nutrition Ten Time:2022.07.15
Guide
In the past ten years, NMN can be regarded as the most popular and best -developed supplement in the field of anti -aging. Since its direct annexal annectors NAD+(nicotinamide glandotide) has been discovered, it has been excavated, including improving muscle insulinin Sensitivity, help immunotherapy to remove tumors, and regulate the intestinal flora [1-5], and the magical effects are constantly, so it is also named "not old medicine".
"Longevity is not old" shouted, attracting countless people with anti -aging. According to incomplete statistics, Hong Kong wealthy businessmen Li Ka -shing, real estate tycoon Pan Shiyi, and the former head of Moutai, Ji Keliang, were all followers of NMN. In the academic faction, Harvard Professor David, far away from the other side of the ocean. Sinckle was a mobilization of the whole family, and even the wonders of "the mother after menopause after taking the NMN monthly wave".
David Schinger mentioned in the book "Longevity · When humans are no longer aging", and at the end of the text, you can directly reach the official book purchase page
Speaking of NMN's improvement of female reproductive aging, it is not unheard of [6]. Recently, a human body clinical that Japanese scholars swords on a Japanese scholar directly invites women to be a subject to explore NMN indicators of human aging associations to human aging associations. Improvement effect [7].
Judging from the results of this clinical trial, only 8 weeks and 300 mgnmn are eaten every day. This group of women who are 55 years old and are accelerated by the age of age can get divine power. As well as, the hormone level is stable and plus, and even the skin becomes white and smooth, and the bomb can be broken.
Seeing this, who can not say anything? Intersection However, when the author pulled the literature down, the details of the research, frowned again, and found that the matter was really "not simple."
At the metabolism level of the body, it seems useful and not exactly useful to eat NMN for 8 weeks.
The first is the level of hormone levels of these 16 middle -aged and elderly women. Under the blessing of the external NMN, the content of DHEA (dehydrogenatone), which should have declined with aging, has increased significantly. However, due to the lack of further exploration, it is necessary to say whether it is good or bad. It is a bit inaccurate. It may indeed help delay aging, but it may also be a good thing to do bad things -people should be reduced at this time.
Caption: The content of DHEA (dehydrogenation table male) in the subject of the subject changes
Secondly, in terms of immune system, data shows that only a group of T -cell sub -groups (NK cells, kill cells, etc.) have changed only a small part of the regulating T cell ratio, but the change in the simple quantity cannot fully explain it fully to explain Immune cell function improves, and even improves the body's immunity.
Caption: The proportion of some immune cells in the subject of the subject changed
Finally, the study also gave the nutrient -sensing system change that was easy to get out of aging. In terms of sugar and lipid metabolism, the performance of NMN is not too disappointing, which not only greatly reduces the blood sugar level of the subject, but also enhances the high -density lipid protein content called "good cholesterol" in their bodies. Essence
Caption: In clinical experiments, the level of blood sugar and high -density lipoprotein in the subject
Regarding the conclusion of "skin rejuvenation and delaying skin aging", which is proud of in this clinical trial, I have to make some questions.
Although the "Excellent Players" who evaluate the aging of the skin (AGES) using the "Excellent Players" who evaluate the aging of the skin (AGES), it is also found that taking NMN to improve the "skin sugarization" phenomenon of the subjects, which can avoid collagen in the tissue. Loss of protein.
Caption: The glycation of the subject's skin has improved
But in addition, the evaluation of the skin condition is more based on the subjective judgment under the visual simulation table, such as: How is your skin's moisture content? Do you feel dry skin? Do you care about the elderly spots? And these are not enough to fully indicate that the skin condition has been significantly improved before and after the experiment.
In addition, after the NMN was eaten in 8 weeks, the aunts' BMI (physical quality index) increased significantly, and the effect of muscle tissue gains that were previously proven by a number of high-quality human body (such as muscle grip) [1-3] But nothing. The more the aunts eat, the fatter, and the muscle strength has not become better ... Wow, this clinical result is really hard to say ...
Time School Comment
Looking at it clinically, although NMN is small and effective, there are really a lot of trial design. For example, the NAD+measurement time is not rigorous, which eventually causes a great deviation of NAD+data, which directly triggers "NMN, NAD++NAD+ The unexpected results of the level without rising and anti -descending ".
However, the research results are indeed unbelievable, but the point of view of the introduction of the author's article is remarkable:
"Physiological aging is the fate of all creatures, which is inevitable. It is more or less due to lifestyle disorders and aging beyond the level of biological physiological. Additional aging beyond this physiological aging can be regarded as pathological pathological Aging can be corrected and recovered by changing lifestyle and medical intervention. "
It may be difficult, but healthy aging is the end point that we are now and can be reached.
—— Timepie- ——
Here is the time for the hardest time to renew the study, focusing on "longevity technology" popular science. The writing of the day to read the literature just to bring you the latest and most cutting -edge anti -aging information to you. Welcome to leave your views and doubts in the comment area; Japan is more motivated from your attention and sharing, and walk alongside you on the way to resist aging!
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