Frequent work, beware of strokes

Text ｜ Xinyu

When most people are ready to sleep, there are tens of thousands of people at work.

These hospital staff, emergency rescue workers, factory operators, etc. belong to 20%of the world's outward work population.

Different sleep -awakening cycles increase their risk of suffering from a variety of healthy diseases, including diabetes, heart disease, cancer and stroke.

Recently, a new study published in "Sleep and Day -Night Rhythm Nerology Biology" shows that even if it is returned to a normal timetable, the adverse effects of work may be lasting.

Picture source: pixabay

"Short class work, especially rotation work, will disrupt our biological clock, which has an important impact on health and human diseases."

The research communications author and David Earnest, a professor at the Department of Neuroscience and Experimental therapy, said, "When our biological clocks are synchronized normally, it will coordinate all the biological processes in the right time during the day or evening. Biological clock disorders, whether it is work or other interference, will change the physiological, biochemical process and various behaviors. "

A previous study of the Earnest team found that compared with animal models working in the 24 -hour day and night cycle, the animal models of rotation work have more severe stroke in terms of brain damage and functional defects, and the male mortality rate is higher.

This new study uses different methods. Researchers did not study the direct impact of stroke work in the rotation class. Instead, all the research objects returned to the normal 24 -hour cycle, and waited until they entered the middle age (the period when humans were most likely to occur) to evaluate the severity and results of the strokes (the period when human beings were most likely to occur). Essence

Although epidemiological studies have found that most people will return to normal working timetables after 5 to 8 years of work, but the study found that the impact of rotation work on health will last for a period of time.

Even if the conventional schedule is restored, the sleeping cycle of the subject who has worked in shifts is difficult to resume normal.

Compared with the control group, their sleep -awakening rhythm has continued to change, and sleep usually occurs abnormal activity.

Once a stroke, in addition to women's more serious functional defects and higher mortality than men, its prognosis is much worse than the control group.

Researchers have observed that the level of inflammation medium in the body of the rotation work is also increasing. Earnest believes that from the perspective of day and night rhythm disorders, some mechanisms that cause more severe stroke may involve changes in interaction between the brain and the intestine.

Now many people no longer work from 9 o'clock to 17 o'clock, but bring their jobs home, sometimes work until late at night. Even those who work regularly are inclined to stay up late on weekends to produce the so -called "social jet lag".

"This will also disturb our biological clocks and no longer maintain a regular time rhythm. All of these may have the same impact on human health as the work of work." Earnest believes.

Earneest said that in order to avoid some of these health hazards, the best way is to maintain the regularity of soberness, sleep and meals, and there will be no great differences every day.

In addition, avoid common cardiovascular risk behavior, such as high -fat diet, excessive drinking, and smoking.

Related thesis information:

https://doi.org/10.1016/j.nbscr.2022.100079

"China Science News" (2022-07-15 The 2nd Edition of the International Title of the Original Title of "Increases Stroke Risk of Strokes"))

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Edit | Zhao Lu

Capture | Guo Gang

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