Sichuan umbilical blood storage found that 10 new genes were recognized by the WHO and officially named WHO

On July 13, the cord blood cord blood stem cell library (hereinafter referred to as the Sichuan umbilical blood bank) announced that the 10 human leukocyte antigen (HLA) of the HLA tissue and matchmaking laboratory was obtained by the World Health Organization Approve and officially named.

"HLA and other genes are actually one of the human blood type, but it is much more complicated than the ABO blood type we usually call the ABO blood type. Everyone has HLA and other genes. Except for the twins of the same oval, two individuals, two individuals The probability of HLA is extremely low, and it can not change for life. It can be used as a hereditary mark. "Li Xingjie, director of the Sichuan umbilical blood bank testing department, introduced.

Sichuan umbilical blood bank HLA tissue matching laboratory

Sichuan umbilical blood storage is one of the seven cord blood stem cell libraries approved by the National Health and Health Commission. It is currently the only legitimate newborn cord blood stem cell collection, testing, preparation, freezing, and ultimately used clinical use in Sichuan Province. Institution, the HLA organization matching laboratory under the library is one of the earliest units in my country to carry out HLA research work. He has more than 40 years of experience in HLA organization matching work experience. It is also one of the first few laboratories that have established and launch HLA-A, B, C, DR, DQ, DP sites.

One of the new discovery of the naming certificate of the allele

Earlier, the Sichuan umbilical blood storage HLA tissue distribution laboratory has found 23 new -level genes named the World Health Organization. In recent years, in the process of conducting umbilical blood storage HLA data, the submission of 10 HLA new and other genes has been completed. After several communication, 10 new equal genes have been named HLA-named HLA- A*24: 556N, C*08: 250, C*08: 249, B*37: 105, B*55: 129, A*31: 01: 49, A*11: 427, C*01: 02:: 87, A*11: 428 and C*03: 603, and the number of newly equal genes found in the laboratory also reached 33.

Li Xingjie also said that umbilical cord blood -making stem cell transplantation can save the life of patients with blood system diseases, and the accurate HLA allocating type is the key to hematopoietic stem cell transplantation. The discovery of new and other genes can not only help patients find organs and hematopoietic stem cell transplantation. More suitable donors, improve transplantation survival rates, and enrich human genetic information, which has important academic value for human science and genetic research in my country.

Cover reporter Zhou Jiayi

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