For more than a decade of vaccine in Wuhan University for more than ten years, why did this infectious disease have not been eliminated?

Whether it is the literary book "Love in the choice" and "White Deer Plain", there have been cholera. In reality, the cholera has disappeared for a long time.

However, on the 9th of this month, a suspected cholera infection was officially reported on the 9th of this month. In the end, the serotics condensate test was O139 positive and diagnosed as cholera. According to the latest official news, the student has been diagnosed and treated, with a stable condition and the symptoms have disappeared.

However, as a disease that occurs in areas of hygiene or backward economic conditions, why appears in Wuhan or even universities, which has aroused great attention from the outside world. Due to high infectious and high mortality, cholera and plague belong to the Class A infectious disease stipulated in the "Prevention and Control Law of the People's Republic of China".

On July 11, a student of Wuhan University told the reporter of "Daily Economic News" through WeChat that the dormitory where the infected students had lived downstairs had pulled up the blockade, and the security guard was on the door. In an interview with the reporter of the Daily Economic News, the virus expert Chang Rongshan said that although the cholera is contagious and the mortality is high, the incubation period of cholera is several to 6 days, usually 2 to 3 days, infected in infection, infected by infection, infection in infection. Symptoms have occurred for several days without new cases, and secondary infections are less likely to occur.

The door of the dormitory where students live in "closed", and there is a security guard at the door

"Love in the choice" is romantic, while cholera is terrible.

On the evening of July 9, the news of a suspected cholera case in Wuhan University quickly fermented. On the 11th, the Health and Health Bureau of Wuchang District of Wuhan City confirmed that the case of infectious diarrhea was mainly vomiting and diarrhea, accompanied by low heat, serotics condensation tests are O139 positive, diagnosed with cholera, and toxic power gene negative.

The latest report shows that after effective diagnosis and treatment, the condition of this case has been controlled and the symptoms have disappeared. Organized professional institutions carry out sampling, detection and tracking management of relevant personnel, and provide temporary control management and disinfection disposal of related places. As of 19:36 on July 10th, a fast inspection was conducted through 264 key groups and 259 points. No new cases were found in O1 and O139 group cholera.

What is the internal situation of Wuhan University when guessing and worrying about gradually calming down? On the afternoon of the 11th, a student of Wuhan University who was still on campus told the reporter of "Daily Economic News" in WeChat that the eight houses of the Ministry of Engineering where the infected classmates lived before were temporary and controlled. The iron door of the dormitory was covered, and the door was pulled on the door, and the security guards were on duty. Occasionally, when there were people entering, they needed to register at the door to enter the dormitory. On the playground near the dormitory, the air network was also seen, and there were no personnel activities.

Eight House of Engineering. Photo source: respondent picture confession

"The other around is normal, and it seems that there is nothing different from time to time. But the shops on the streets of Gongba Eight are closed." The classmate said, "I don't know which day it is closed, but the boss said before that they did not say that they did not not. For the summer vacation, it is now closed. "

The reporters have repeatedly dialed the Wuhan University Hospital and the Wuchang District Health and Health Bureau to understand the relevant situation. The staff said that no interviews are currently not accepted. All information is subject to official official notifications.

According to the latest notice from the Wuchang District Health and Health Bureau, the infected students have determined that the three -person secretly connect (2 people who live in the same roommate and 1 person in the same meal) have been transferred to the school isolation point to concentrate. In the early morning of the 10th, the sampling work of 254 students, 3 centers, and 15 merchants in the eight houses of the Ministry of Engineering and Sciences had temporarily closed control in the relevant areas. Relevant personnel were isolated as required and took preventive drugs.

For medical staff and inspectors who were in contact with the infected students on July 8th, 19 diarrhea cases that had been visited by Wuhan University Medical College since the 1st to 10th were sampled as required and held tasting of cholera. Environmental sampling and ending disinfection of dormitories, dining, and small sales department have been carried out, and relevant personnel should take preventive drugs and home observations.

"Very contagious and high mortality", the cholera is a Class A infectious disease and the level is higher than the new crown

Chois, ceiling, plague, these infectious diseases that have been smelled, because they rarely appear, and they have been mistaken for the depths of history or literary works. But in fact, such diseases have not been eliminated.

According to the classification of infectious diseases in the "Prevention and Control Law of the People's Republic of China", the infectious diseases stipulated in my country are divided into three types: A, B, and C. The only two of them were listed as cholera and plague. Once a case of class A infectious disease is found, whether it is a city or a rural areas, it must be reported to the local disease control center within two hours. standard.

Although the new coronary virus pneumonia, infectious atypical pneumonia belong to Class B infectious diseases, it is managed by reference to Class A infectious diseases.

In an old article published by Zhang Wenhong, the director of the National Infectious Disease Medical Center, mentioned that "cholera is a rare infectious diseases that are rare, extremely mortality, and widely popular in the hemisphere of east and west. In areas where hygiene conditions are not guaranteed, cholera still threatens people's lives. "

As an acute intestinal infectious disease caused by cholera, cholera has caused seven worldwide popularity since the beginning of the 19th century. In the 1990s, with the emergence of O139 serum group cholera, the trend of global choice is even more severe, which has led to tens of millions of people to die.

In recent years, there have been less cholera, but it has never really disappeared. According to the official website of the China Centers for Disease Prevention and Control, my country has been affected since the seventh choice world popular in 1961. Except for Tibetan caseless reports, the remaining provinces have epidemic conditions. Since 1993, some areas of O139 cholera have appeared in some parts of my country. Subsequently, a mixed population of bacterial groups (types) appeared. However, with the development of modern epidemiology and microbiology, and the improvement of the modern urban environment, the number and mortality of cholera cases in recent years have significantly declined. According to data from the China Centers for Disease Prevention and Control, in 2021, there were 5 cases of choice reported in the country, and there were no death cases.

In 2021, infectious diseases and death data. Photo Source: Health and Health Committee website

Although the number of diseases in recent years is declining, as a category of infectious diseases, the lethality of cholera cannot be underestimated. First of all, the cholera is "highly contagious". The source of cholera is a patient and a fungus. The excrement and vomit of cholera patients contain a large amount of cholera. Those include incubation period with bacteria, recovery period, and healthy band. Although there are no typical clinical manifestations, they can be moved everywhere.

Its main transmission pathway is the spread of manure, that is, "the illness comes in from the mouth." In addition, if the skin is contaminated with cholera, not paying attention to hygiene and not paying attention to washing, it may also lead to contact infection.

In addition, the choice is "very high." After the infection cholera, the infected person is mainly manifested in diarrhea, vomiting, and "rice -like". Those with severe shocks can be complicated with acute renal failure. After the disease, the cholera may cause diarrhea and even death in the infected person within a few hours. Even if you do not eat, you will continue to be diarrhea. In severe cases, muscle spasm and other symptoms will occur, with a mortality rate of 12.8%.

According to the "National Joined Testing Plan (Trial)" released by the China Centers for Prevention and Control, the performance of heavy cholera includes more than 20 times a day, extremely irritable or even coma, the skin elasticity disappears, the eye sockets are deep, obviously stingy, seriously stubborn, serious Muscle spasm, weak pulse and fast or even no pulse. The degree of dehydration is equivalent to more than 10%weight and 8%adults.

The possibility of the martial arts cholera epidemic spread is low, and the vaccine has appeared more than ten years ago, but the vaccination rate is low

In recent years, cholera has appeared in areas of public health or backward economic conditions. This appeared in Wuhan, and it is also a high degree of attention and discussion. The reporter has noticed on the official website of the Health Commission of Hubei Province that in the past two years, Class A infectious disease has not occurred in Hubei Province. The cholera cases of Wuhan University should be the first case of Class A infection in Hubei Province in recent years.

Virus expert Chang Rongshan said in a telephone interview with "Daily Economic News" that cholera cases are most common to be infected by intake of food or water contaminated by cholera. If the case of infection is not drinking the raw water containing cholera, it may be caused by eating foods with cholera.

Chang Rongshan said that because water sources are important ways to spread the transmission of cholera, in the past, there were more frequent coastal areas. Natural water such as coastal waters, estuary and inland river, and lakes were all natural living environment for cholera. Frequent pollution people are near the water body. The case of infection may not be eaten with light, seawater or other unclean foods that have not been sanited and deeply processed.

However, because cholera can also be transmitted through contact, it is very important for the activity trajectory and investigating people to investigate the cases of flow infection. According to the latest situation released by the Health and Health Bureau of Wuchang District in Wuhan City on the afternoon of July 11, as of 19:36 on July 10, the fast inspection was performed on 264 key groups and 259 points. Pepsi, no new cases were found.

Chang Rongshan said that because the incubation period of the choice is several hours to 6 days, usually 2 to 3 days, and the infection cases have symptoms on the 8th, and the possibility of new cases and larger ranges now occur.

He also explained that due to the infectious period of case excrement in the period of positive onset. Occasionally, the infectious period of the carrier lasted for several weeks. Therefore, the disinfection of the internal and infected activities of the student dormitory of Wuhan University is currently important. The Wuchang District Health and Health Bureau also stated in the latest instructions that the environment samples and endless disinfecting of the public areas, dormitories, bathrooms, and sewage pipelines of the Ministry of Engineering.

In fact, there is no way to prevent cholera infection. As early as 2005, the new oral RBS/WC choice vaccine developed by the Institute of Biological Engineering of the Academy of Military Medical Sciences had been released. However, public information shows that the vaccine mainly has a preventive effect on group cholera, and this time Wuhan discovered the O139 group. Chang Rongshan also said that because the vaccine also has certain side effects, it is mostly used for high -risk personnel or regions, and is not suitable for vaccination.

For the treatment of infection, Chang Rongshan said that as long as it is found in time, antibacterial drugs can be given while liquid treatment to reduce diarrhea and shorten the period of bacteria. According to the source of drugs and the sensitivity of the popular choleramia against bacteria, a commonly used antibacterial drugs are selected. The commonly used antibiotics are fluoropromic acid and tsaropenia.

Daily Economic News

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