After taking antihypertensive drugs, why is the kidney damage, is it related to the drug?
Author:Pharmacist Huazi Time:2022.07.09
A friend told Huazi that he didn't want to take the level of antihypertensive drugs anymore. Hua Zi asked him why? He said that Horizon's antihypertensive drugs will hurt the kidneys, and the kidneys will be bad after a long time. One of his friends was like this. After suffering from high blood pressure, he had been taking medicine. As a result, he took 10 years of medicine and now suffers from uremia.
Hua Zi told him that the person who suffered from uremia was definitely not because of the medicine. Hypertension is the culprit that hurts the kidneys, and the role of antihypertensive drugs is to protect the kidneys. The reason why kidney damage occurs is likely because the antihypertensive drug is unreasonable and does not control blood pressure.
1. How to harm the kidney at hypertension
Hypertensive damage to the kidneys mainly occurs from two aspects. First, the pressure of blood pressure increases, leading to high irrigation, high filtration, and high -span membrane pressure of glomerular balls. The pressure in the glomerular balls increases and directly causes damage to the kidney. Excessive blood pressure can damage the epithelial cells of the renal tubular, leak macromin protein, and block the renal screen system.
Second, hypertension causes damage to the kidney arterial system. The pulse pulse -shaped sclerosis occurs. The arterial lumen becomes narrow.
After kidney ischemia, it will cause increased renal secretion, and further aggravate hypertension through the "renin-vascular tension-aldosterone" system (RAAS) system (RAAS). In other words, hypertension and kidney injury will be causal and form a vicious circle.
2. How long will high blood pressure hurt the kidneys
The human kidney has a huge compensation effect. The human body has two kidneys. Each kidney has about 1 million kidney units. About one -third of the kidney unit can meet the needs of the daily metabolism of the human body. As long as the kidney unit needs If the loss does not exceed 70%, there will be no obvious symptoms.
Although hypertension can cause kidney damage, this is a long process. Generally speaking, it takes 5 to 10 years to not be controlled by high blood pressure to cause obvious kidney damage. As long as blood pressure can be controlled in time, kidney damage can be avoided. In the early stages of kidney damage, it was found that as long as the blood pressure was controlled in time, the disease progress can also be delayed to avoid entering the uremia period.
Third, the blood pressure must be controlled to protect the kidneys to protect the kidneys
Excessive blood pressure is the main mechanism to cause kidney damage. Therefore, the pressure reduction is to protect the kidney. After taking antihypertensive drugs, people who still have kidney injury will still cause kidney injury. Basically, the use of medication is unreasonable, resulting in the inadequate blood pressure control.
Many people think that everything is good after taking the antihypertensive medicine, and does not measure blood pressure. It only feels that the control of the blood pressure does not meet the standard. As a result, the hypertension has been hurting the body, but I don’t know. After the injury, I was wondering because I took medicine and had broken the kidneys.
The diagnostic standard for hypertension is 140/90mmHg, the target of blood pressure control is usually 130/80mmHg, and the ideal blood pressure is 120/80mmHg. People with hypertension must measure blood pressure when taking medicine to ensure that blood pressure meets the control goals.
Fourth, what to do to protect the kidneys
Controlling blood pressure standards is the most important method of protecting the kidney. Among the antihypertensive drugs, Satan and Prilyn have a strong inhibitory effect on RAAS and have the effects of kidney protection. You can use Satan or Puli as a basic medication, use other antihypertensive drugs, and try to control blood pressure near the ideal indicator.
To control the intake of salt in the diet. Salt should not exceed 5 grams per day, which can reduce blood pressure and reduce the burden on kidney regulation. The nitrogen generated after protein metabolism needs to be discharged through the kidneys, so people with bad kidneys should control the amount of protein intake, and do not eat too much foods such as beans and meat.
To sum up, antihypertensive drugs will not damage the kidneys, and the high blood pressure that is not controlled is the culprit to hurt the kidneys. When taking antihypertensive drugs, blood pressure must be measured to achieve blood pressure standards in order to effectively play the protective role of the kidneys. Regular physical examinations are required every year to check renal function -related indicators and discover problems in a timely manner. The use of drugs needs to be performed under the guidance of a doctor. If you have doubts about medication, please consult a doctor or pharmacist. I am a pharmacist, and welcome to follow me and share more health knowledge.
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Inherit the virtueKang Haichao is a member of the party group of Chengde Municipal Government, a member of the Municipal Party Committee Political and Legal Committee, and the secretary of the Party C