Undergraduate students published papers in international journals in the field of biological information science

Recently, Lu Jiaqing and Yao Yan's academic papers "Small Protein Complex Predict on Protein-ProTein Internet Network Segmentation" by the senior undergraduates of the ACM Practice School of the University of Technology Innovation and Entrepreneurship. The first author and second author of the paper, Teacher Liang Bing, the Innovation and Entrepreneurship College, is the instructor of the paper. BMC BioInformatics is an important journal in the field of biological information and computing biology. The second area of ​​SCI has an influencing factor 3.242. Focusing on computing and statistical methods for modeling and analysis of biological information data.

Recognizing protein complexes from protein interaction network is one of the important tasks of the post -genome era. But so far, the protein complex identification method has not performed well in small protein complex identification. As members of the ACM practice class design competition player, Lu Jiaqing and Yao Yan used the minimum generating tree algorithm learned in the program design competition for the first time to solve the problem of protein complexal identification, which proposed a new method called BOPS (BOPS (BOPS (BOPS (BOPS (BOPS (BOPS , Based on PPIN Segmentation), this method first calculates the balance weight to replace the original weight; continuously divides graphics greater than MAXP until the original PPIN is divided into small networks; finally listed the connection subset of each small network to determine the potential protein to determine the potential protein. The complex and delete those too similar. Compared with the SOTA model, the performance has increased by about 5%, and a new opinion of the small protein complex recognition method is given. This study application computer algorithm predicts the protein complex in the protein interaction network. Through the cross -scientific advantages of biology and computer scientific integration, the costs and materials required for biological experiments are reduced to provide reliable biological experiments with reliable biological experiments to provide reliable biological experiments. Guidance and help.

Figure BOPS algorithm description

The ACM Practice Class of Innovation and Entrepreneurship College uses algorithm design and programming competitions as a platform to provide college students with an environment that uses computers to fully display self -analysis and problem -solving capabilities. It has cultivated a large number of high -quality and high -level computer program design talents. The design competition "ICPC International University Student Program Design Competition" won 6 gold medals, 56 national awards, 58 provincial and ministerial awards.

The results were funded by the provincial college student innovation and entrepreneurial project "Research on the Research on the Complex Identification Algorithm in the Protein Interactive Network".

News source: Dalian Polytechnic News Network

Edit: Ji Ying Ce

School pair: Li Yixun

- END -