Write a letter to myself five years later | Guo Junling, a professor at Sichuan University: From Harvard to Sichuan University, I brought international first -class scientific research concepts back to "home"

Guo Junling, 34 years old, one of the youngest professors and bloggers in Sichuan University. He studied and worked at Sichuan University, University of Melbourne, Harvard University, and has multi -disciplinary background knowledge such as materials science, chemistry, biomedicine. In 2019, Guo Junling left Harvard University and joined the School of Light Industry and Engineering, Sichuan University. Through the high degree of intersection and integration of multidisciplinary disciplines, a series of innovative achievements and technologies in biomedical, environment and energy, future agriculture, reproductive medicine and other fields have been developed.

Guo Junling is in scientific research.

Scientific research results ascend to "Nature-Communication"

Not long ago, Guo Junling led the team to publish a recent research on "Nature-Communication". They invented a "armor live bacteria" technology, which is expected to treat the intestinal tract-related major and difficult to treat diseases. At present, the research has completed animal experiments and is expected to enter clinical research soon.

Guo Junling introduced that many intestinal and digestive -related diseases are clinically treated, and they often depend on antibiotics, especially in the face of the most common harmful bacteria in the intestine. Once the human body is infected with this bacteria, intestinal disorders will occur slightly, and severe life will be crisis. Antibiotics are the only effective means to deal with "difficultyl bacteria". Essence

Recently, Guo Junling and Dr. Zhang Yaoyao, Harvard Medical College, Massachusetts Institute of Technology, and Huaxi Second Hospital of Sichuan University, developed a new type of "nano armor" package technology. "Package" built nano -engineering bacteria. Animal experiments have shown that this "armor" can provide effective protection for good living bacteria, so that it can be exempted from 7 common antibiotic violations in clinical clinical, which can greatly improve the survivability of oral lid bacteria in the human intestine.

Prior to this, Guo Junling also jointly developed a nano -spray with low cost, high safety performance, natural and environmentally friendly, and simple operation, which has a strong elimination capacity for the new crown virus. This technology has entered the stage of trial industrialization and is expected to be sold for the market this year.

Establish a cross -disciplinary research team to realize the "combination of medical workers"

After graduating from the Department of Leather and Biomass of Sichuan University, Guo Junling went to the University of Melbourne, Australia to study a PhD. Professor Samir Mitragotri, a well -known drug delivery expert, American Medical College, and the School of Engineering. After Guo Junling returned to Sichuan University with full position, he became one of the youngest professors and doctoral tutors of the university.

Many people are curious, how can the blog director of the School of Light Engineering Science and Engineering engage in research related to biotechnology? Guo Junling explained to this that this would be due to the development concept of Sichuan University's "combination of medical workers".

The subject of the School of Light Engineering Science and Engineering is the major of leather chemistry and engineering, which has always been a trump of Sichuan University. After the reform and opening up, China's light industry has ushered in huge development, and the Sichuan Grand Leather majors have also developed and contributed to the economic and social development of the country. However, with the development of society and technology, the discipline development of "leather chemistry and engineering" has entered a bottleneck stage. "Transformation and upgrading" has become an important development concept of "leather chemistry and engineering" discipline.

In 2017, Academician Shi Bi, a professor at the School of Light Industry and Engineering of Light Industry and Engineering in the field of Chinese leather chemistry and engineering, suggested that Guo Junling returned to his alma mater and introduced the cross -disciplinary ideas of top international research institutions into the development of disciplines. After that, Guo Junling gave up the excellent treatment overseas and returned from Harvard University to Sichuan University. With the support of the national key discipline construction and the support of the national talent plan, the advanced biomass and nano interface research centers were formed.

The center uses the "plant polyphenols" widely existed in the light industry and the construction industry, also known as "plant tannins" as the research foundation. It uses its natural physical chemistry and biological activity to synthesize a series of special nano structures Advanced functional materials are used in the fields of biotechnology, environment and energy, biomedicine and other fields, solving key science and application problems in cross -sectors.

It is worth mentioning that Guo Junling shared the latest major research results of the team, which can apply polyphenol nanomaterials to auxiliary reproductive technology. The implantation of fertilized egg embryos in the uterus is the core scientific issue of assisted reproductive technology. Guo Junling's team cooperated with experts from Huaxi Second Hospital to wrap a layer of nano -capsules on the surface of the embryo surface, which can increase the embryo in the uterus in the uterus. Rate. At present, this technology is conducting animal experiments to comprehensively verify its effectiveness and biological safety. I hope to develop more original new technologies and cultivate more outstanding talents

Guo Junling led the team through innovation leadership and green development, and strived to promote the transformation and upgrading of my country's light industry discipline and industry. Through the cross -integration of multidisciplinary disciplines, he aimed at the major needs of the country and society. The recognition of colleagues, in the internationally renowned "Nature", "Cell" and "Science", was published in a series of journals called "NCS", which showed their cross -domain results.

I have been asked many times, why choose to return to Sichuan University? Guo Junling proudly said: "I am from Chengdu. Leaving my hometown to study and work overseas, I look forward to giving back to my hometown and giving back to my alma mater." Guo Junling said, "Chengdu, like my mother witnessed my growth and study. In the decade of overseas, my thoughts on my hometown have always been accompanied by me. I also pay attention to the development of my hometown in terms of economy, culture, science and technology at any time. Now that I have returned to my alma mater, I have the opportunity to take the international first -class scientific research concept and talent. The training mode is brought back to 'home'. "Guo Junling said that he should be grateful to the country's opportunities to create in this era, so that scientific researchers have more opportunities to develop research results into new technologies and products.

Talking about the desires of five years later, Guo Junling hopes to develop more original new technologies and cultivate more outstanding talents.

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