Drinking coffee actually has this role?Gospel of gout patients!

Author: de novo

Summer is here, the most fascinating is to blow the evening breeze with seafood beer. But be careful, a bite of seafood and wine, the crystallization of uric acid is full, and the gout will also come with the evening wind!

Different drinks will cause different risk of gout. For people who love drinking or drinking high sugar drinks, they will have greater risk of gout.

How painful is gout?

"Whether it is the nail nail, the restraint of the rope, or the scratching of the dagger, and the burning of the fire, it is not painful." As early as the first century AD, the Greek doctor CAPPADOCIA made the gout on gout. Such a description. [1]

It is not difficult to see that after suffering from gout, the quality of life of patients will decline sharply, and some of them cannot even take care of themselves.

How is gout formed?

Gout is a metabolic disease that is directly related to human uric acid content. If the content of uric acid in the body is too high, uric acid is crystal and accumulate at the joint. When the body exercises, the joint friction will cause severe pain. Therefore, during the physical examination, the high serum uric acid content can mean that gout risk is greater. At this time, it is often necessary to control diet and living habits, but it is worth noting that the high serum uric acid content does not necessarily suffer from gout. Preventing uric acid crystals is the key to staying away from gout.

Crystallization of uric acid (by the author)

Uric acid is the metabolic product of purine. It is slightly soluble in water and is easy to crystallize. About 1.1 grams of uric acid in adult human body is one of the important compositions of non -protein nitrogen sources in plasma. If you eat high purine foods for a long time, such as seafood, soy products, etc., it is easy to cause high uric acid content in the body. In addition, after drinking, alcohol metabolic lactic acid can inhibit the normal metabolism of uric acid, which can easily cause uric acid retention in the body. When the content increases exceeds the critical value, it will form crystallization and cause gout.

Garlic Oyster (Author shooting)

Can coffee reduce gout risk?

However, it is surprising that a recent survey in Japan shows that drinking coffee seems to be related to the decrease in the risk of gout. [2] Researchers compared the drinking situation of coffee, serum uric acid content and gout incidence of more than 150,000 people. As a result, the serum uric acid content of the investigated population was not significantly related to the consumption of coffee, but the incidence of gout's incidence However, it is significantly related to the consumption of coffee. The proportion of people with gout with coffee people who drink coffee is relatively low.

A recent study on the gout model of mice also proves this statistical result. Brazilian scientists treat mice with gout with gout with coffee extract. Coffee may become a potential candidate for acute gout treatment. [3]

However, whether coffee can really reduce the symptoms of gout, the conclusion is unclear, and its principle is still unclear. One of the possible reasons is some metabolites produced by metabolic compounds in coffee (such as caffeic) during metabolism in the body, such as cocoa [4], which may have an efficient inhibitory effect on the crystallization process of uric acid, and and and and and also, and It may promote the dissolving of uric acid crystals to reduce the risk of gout. [5] However, the pathogenesis of gout is very complicated, with many influencing factors. These cutting -edge research results are still in the theoretical research stage. Scientific drug treatment is still the main way to treat gout at this stage.

Caffeine, cocoaine, uric acid chemical structure (drawn by the author)

How to prevent gout scientifically?

There are many ways to prevent and relieve gout. Among them, drinking plenty of water, more exercise, and regular schedules are the highest. And when you find that serum uric acid content is too high, on the one hand, you need to reduce the intake of purine foods, such as eating less seafood, soybean products, and animal viscera. On the other hand, we must pay attention to avoiding the metabolism of your own uric acid, such as alcohol, high sugar fruits, and fructose in beverages, which will inhibit the discharge of uric acid from the body, so it will also lead to increased serum uric acid content and increase risk of gout.

Thinking questions: Xiaoming has 425 brown crayfish, 167 garlic scallops, 396 grilled oysters, 10 boxes of beer. Today, Xiao Ming drank 1 box of beer, eaten 81 crayfish, 26 scallops, and 14 oysters. What is Xiao Ming now?

Answer: gout (bushi)

references:

[1] Barnett R. Gout [J]. The Lancet, 2018, 391 (10140): 2595.

[2] Shirai Y, Nakayama A, Kawamura Y, et al. Coffee Consumption Reduces Gout Risk Independently of Serum Uric Acid Levels: Mendelian Randomization Analyses Across Ancestry Populations[J]. ACR Open Rheumatology, 2022, 4(6): 534.

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