hard power!New breakthrough!

Author:Jinan University Time:2022.09.21

Jinan University

Public account ID: jinandaxue1906

Each knowledge of knowledge

It is inseparable from the hard work of scientific researchers

Let's take a look together

In the past for a period of time

Jinan teachers and students

All scientific research results obtained

Professor Li Xiangping's research results

Selected into the National Natural Science Foundation of China

2021 Report results tour

Recently, the National Natural Science Foundation of China issued the "National Natural Science Foundation of China 2021 Annual Report", which summarizes the National Natural Science Foundation of China 2021 applications and funding and important achievements. Among them, Professor Li Xiangping and collaborators of the Our Our Our Optometer Research Institute have made important progress in the "multi -dimensional rail corner volume information reuse", and selected for the funding for the report of the report, becoming one of the forty important funding results.

With the support of the National Nature's Outstanding Youth Science Fund Project (61522504) and the National Natural Research Plan (91750110), Professor Li Xiangping's team and collaborators of Jinan University have found that OAM light accumulates oval in the scorched spots under the focus The dependence of the long -axis space orientation of the OAM optical topological lotus reveals the new physical phenomenon of the spiral dual -colored (HD) that is formed by the differences in the absorption of particles caused by the OAM light field. Combining this phenomenon with the light and thermal formation of the golden nanoparticles, the first six -dimensional (orbital angle, wavelength, polarization, and three -dimensional space) light information is achieved in the nano -scale. The above results were published in Nature Photonics, 15: 901, 2021 in the top of the optical field. The research work has opened up new ways to control the interaction between light and material, and has important application prospects in related fields such as large -capacity information storage and optical encryption.

Original connection:

https://www.nsfc.gov.cn/publish/portal0/tab1381/info86741.htmm

Wu Jianguo's team is in

Influenza virus regulation interferon mechanism

New progress has been made in research

9月7日,国际学术期刊PLoS Pathogens杂志在线发表了暨南大学吴建国教授团队的最新研究成果,论文题目为“Enzymatic independent role of Sphingosine kinase 2 in regulating the expression of type Ⅰinterferon during influenza A virus infection”。 This study revealed the new mechanism of type A influenza virus (IAV) infection and synthesizing virus replication through the synthesis of type Ⅰ interferon synthesis through the hosts of the hosts.

The study revealed that flu virus uses the main cause of the loscology amphenosylinase SPHK2 to promote its own replication mechanism with a very delicate mechanism: after the influenza virus is infected with the host cells, the intracellular SPHK2 protein increases and enters the nucleus. In the nucleus, SPHK2 interacts with HDAC1 interaction with HDAC1 , SPHK2 substrate combined area is interacted with TET3 combined with the TET3 on the IFN-β promoter, so that the IFN-β promoter is removed to inhibit the transcription of IFN-β promoter, thereby inhibiting IFN-β synthesis, and then promoting the influenza influenza The virus itself copy (Figure 2). Different from the mechanism of SPHK2 and HDAC1 regulating C-FOS and P21 transcription (hait et al., Science2009; 325 (5945): 1254-1257.) The influenza virus evasion of the host's immune molecular mechanism provides new insights and further broaden our awareness of interaction with the influenza virus and host.

Xu Mengqiong, a doctoral student of the Institute of Microbiology, Jinan University, and Dr. Xia Sisi, a lecturer in Wuhan Light Industry University, as the first author of the paper, Professor Wu Jianguo, Associate Professor Chen Jun, Professor Li Hongjian, and associate professor of Dalian Medical University as the common communication authors of the paper.

Original link:

https://pubmed.ncbi.nlm.nih.gov/36070294/#

Associate Professor Li Yuchao and others

Advanced Materials Publishing Papers

Recently, Associate Professor Li Yuchao of the Nano-Optical Research Institute and Professor Jiang Lingxiang, South China University of Technology, have made important progress in the study of accurate space-time control in the optical and thermal phase separation of micro-droplets. In the liquid phase separation solution system of heating and phase -modus, a programmable and accurate time and space control of the phase separation of micro -droplets is achieved. Related results were published in the international academic journal Advanced Materials and were selected into the Editor ’s Choice papers and Inside Back Cover.

Associate Professor Li Yuchao and his collaborators combine the multi -torment of the time -sharing reuse and the high -efficiency light thermal effect of the metal nano -thin film to convert the light field into a precise hot field, so as to induce the heating and changeable material system, induces the material system to induce the temperature and change. The light and heat phase with high time and space response is generated separated by micro -droplets. Further, using the hot hair and dynamic reshaping characteristics of the micrust droplet, driving the microver droplet with the scanning path of the laser to synchronize the synchronization, realizing the positioning/movement, fusion/division, and dynamic reconstruction of the microver droplet can be available. The precise control of programming has obtained the spatial accuracy of the sub -micron and the time accuracy of 100 milliseconds, and shows the static/dynamic liquid pattern and music visualization of high -fidelity. Applications of/transport/transport and chemical microchemicals. This type of light-thermal-Lifo physical field coupling control technology provides a new method of high time and space accuracy for the control of micrust droplets. Have important application prospects. The first author of the thesis was Chen Xixi, the post -doctoral research institute of the Nano -Optical Research Institute, and Huang Danmin, a master's degree in the School of Chemistry and Materials of Chemical and Materials.

Thesis link: https://onlineelibrary.wiley.com/doi/10.1002/adma.202205563? AF = R

Professor He Rongrong's team published three high -level papers

Revealive phospholipid peroxidation to increase the disease -prone mechanism of disease

The team of Professor He Rongrong of the School of Traditional Chinese Medicine published three high -level papers during a month. Related research results were published in the international authoritative journal Redox Biol (IF = 10.787), Signal Transdu and Targeted therapy (IF = 38.104), and Redox Biol (if = 10.787), the Sttt published papers were selected as a magazine cover story.

1. Redox Biol (IF = 10.787) | Phosphoric oxidation hinders auto -stilling film!

The team published a topic in the top issue of the oxidation stress field (the Chinese Academy of Sciences JCR Journal 1, IF = 10.787 in 2021) published the title "Phospholipid Peroxidation inchits Autophagy Via Stimulating. Jinan University Guangdong Province's disease and the research and development engineering technology research center of Chinese medicine is the first unit, and Dr. Li Wen, a doctoral graduate, is the first author. Professor He Rongrong of Jinan University and Professor Sun Wanyang as the author of the communication author, and the collaborator Professor Li Min University of Sun Yat -sen University is the author of the communications.

2. STTT (IF = 38.104) | Proposal for myocardial ischemia and re -irrigating the new theory of damage to the incidence mechanism to enrich the scientific connotation of "phlegm and stasis interoperability" in the theory of Chinese medicine!

在Nature旗下国际权威期刊Signal Transduction and Targeted Therapy(中科院JCR期刊1区,2021年影响因子IF = 38.104)发表了题目为“ALOX15-launched PUFA-phospholipids peroxidation increases the susceptibility of ferroptosis in ischemia-induced myocardial damage” Research papers. Jinan University Guangdong Province's disease -sensitive and traditional Chinese medicine R & D engineering research center is the first communication unit, and Dr. Ma Xiaohui, a postdoctoral post doctors of Chinese and Western Medicine Traditional Chinese University of Traditional Chinese and Western Medicine, as the first author, Professor He Rongrong and Professor Li Yifang of Jinan University. Researcher Hongcai, a University of Traditional Chinese Medicine, and Chen Yang, a researcher at Guangzhou University of Traditional Chinese Medicine, is the author of the joint communication.

3. Redox Biol (IF = 10.787) | Reveal the new mechanism that affects embryonic bone development during pregnancy!

8月20日,该团队在氧化应激领域顶刊Redox Biology(中科院JCR期刊1区,2021年影响因子IF = 10.787)发表了题目为“Phospholipid peroxidation-driven modification of chondrogenic transcription factor mediates alkoxyl radicals-induced Research papers in Impaairment of Embryonic Bone Development ". Jinan University Guangdong Province's disease -sensitive and traditional Chinese medicine R & D engineering research center is the first communications unit, Niu Jie, a doctoral student of the School of Pharmacy of Jinan University, is the first author of the master, Master Wan Xin, Yu Guiyuan, and Jiang Shan as the first author of the joint. Jinan University Professor He Rongrong and Professor Li Yifang are mainly communications authors, team member Duan Wenjun, and Dr. He Jianbo, a postdoctoral communication author. Jinan University Guangdong Province's Ethical and Traditional Chinese Medicine R & D Engineering Technology Research Center was founded in 2003 by Professor Kurihara Hiroshi, the winner of the People's Republic of China International Cooperation Award. Duan Wenjun, Sun Wanyang, Liang Lei, Wu Yanping, Ouyang Shuhua, etc. are research backbones. The team is mainly engaged in the basic research of biomedicine that is pathogenic and pathogenic of traditional Chinese medicine, and focuses on "disease-like sensibility" as the starting point of theoretical research. Focusing on the stress of emotional inscriptions, the pathological mechanism of the oxidation of endocrine-immunohistic networks. Dedicated to innovate the establishment of a Chinese medicine evaluation system for "disease -sensitive".

Tensor research group is in social behavior

Important progress in the field of neural mechanism

Recently, the tension research team of Guangdong, Hong Kong and Macau Central nervous regeneration research team hosted by the Chinese Academy of Sciences (IF = 23.2, JCR comprehensive journal ranking of 4/73, listed in the journal of China Science and Technology Periodical Journal), published it. Title "Amygdala Neural Ensses Mouse Social Investigation BehaviViViViors" was first discovered for the first time the gastrointectoma polypeptide hormone (BLA) brain area (BLA) brain area (BLA) brain region (BLA) brain area. Regulation.

This study reveals a new type of almond nucleus neural cluster, which media the instinctual social behavior of mice through specific molecular, neurophysiology, and ring road connection. This result suggests that the almond nuclear system may play a key role in social information processing. At the same time, the improvement of social obstacles confirmed by this study has also provided a basis for clinically alleviating different types of social defects in the clinic.

The thesis work was independently completed by the “Central nervous regeneration” key laboratory platform relies on the “Central nervous regeneration” of the “Central nervous regeneration”. It was supported by Academician Su Guohui at Hengan University and Professor Billy K Chow of the University of Hong Kong. Associate Researcher Zhang Li is an independent communications author in the article. The first author of the paper is the University of Hong Kong-Jinan University jointly trained the doctoral student Wei Ji'an, and the first authors of the joints include Han Qing and Luo Zhihua of Jinan University. This project has obtained fund funding for the major special projects of the Ministry of Science and Technology's "Brain Science and Brain Studies", the National Natural Science Foundation of China, and the special fund of the Guangzhou Municipal Brain Science.

Thesis link: https://doi.org/10.1093/nsr/nwac179

Feng Tianhua's research group in the field of optical information security

Research progress

Recently, Feng Tianhua's research progress has been made in the field of optical information security in the field of optical information security. "Metasurfaces" was published on August 31 on August 31 on the flagship journal "Optica" (Journal of the Chinese Academy of Sciences, 10.644). Ou Yangmin, a graduate student at the Department of Electronic Engineering at the School of Information Science and Technology of Jinan University, is the first author of the results. Deputy Researcher Feng Tianhua of Jinan University and Professor Li Zhaohui of Sun Yat -sen University are joint communication authors. Essence

In the early stage, the use of Metasurfaces (two -dimensional array of micro -nano -structures) is used in optical operations to achieve mathematical operations in optical forms (published in the international authoritative optimum school magazine Photonics Research and was selected as the current Editors' Pick, the first zone of the Chinese Academy of Sciences, the influence factor 7.254) Based on the research, the research group of Associate Researcher Feng Tianhua cooperated with Scholars such as Professor Li Zhaohui of Sun Yat -sen University and Professor Zhang Cheng University of Science and Technology of China and verified that the super surface can be encrypted in the Fourier Space frequency domain of the light field through experiments. So as to overcome most of the current work to encrypt the information on the super surface, so that the information transmission and decryption high depends on the inefficient problem of hardware. The research results are expected to provide reference for various application scenarios, such as biological characteristics recognition, security monitoring, industrial detection, and medical imaging. Article link: https://doi.org/10.1364/optica.463888

https://doi.org/10.1364/prj.426827

Wang Yifei's team revealed Alzheimer's disease

Small glue cell high expression gene

MAMDC2 regulate neurovirus

Anti -virus -induced antiviral natural immune response

Recently, Professor Wang Yifei of the Department of Cell Department of Life Sciences and Technology Institute in the British Infectious Association Journal of Infection (ranked fourth (4/94) in JCR Infectious Diseases Magazine, IF = 38.637) published entitled "MAMDC2, A Gene Highly ExpressEd in microglia in experimental models of Alzheimers Disease, positively regulates the innate antiviral response during neurotropic virus infection” 的研究论文,该研究揭示了MAMDC2促进嗜神经病毒感染小胶质细胞诱导的先天性抗病毒免疫,为理解AD和The contact mechanism between HSV-1 provides new clues.

The study reported that MAMDC2 is regulating small glue cells to a natural immune response to the antiviral virus of neurovirus, which provides a new insight for the regulation mechanism of small glue cell I-IFN reaction when studying neurotic herpes herpes virus infections. It clarifies the clarification MAMDC2 regulates the natural immune response mechanism of small glue cells, and provides new ideas and new theoretical basis for comprehensively analyzing the mechanism between HSV-1 and AD.

Jinan University is the first communications unit, Wang Yiliang, a doctoral student at Jinannan University Student Sciences (currently the postdoctoral post -doctoral post of the National Key Laboratory of Respiratory Diseases). The work is supported by the National Natural Science Foundation of China (No. 81,872,908 and 82,072,274), and the Guangdong Natural Science Foundation (No.2019A1515010046) and other projects.

Thesis link: https://www.journalofinfection.com/article/s0163-4453 (21) 00595-8/fullText

Professor Lou, Professor Li Juan, etc.

At Laser Photonics Reviews

Published papers

Recently, Professor Zhu Jun, Professor Zhu Juan, and Professor Li Juan of the Nano -Optical Research Institute. Reviews.

Due to its unique luminous nature of nanomaterials on rare earth, nanomaterials have broad application prospects in the fields of fluorescent marks, biological imaging, and photoelectric detection. How to effectively enhance the transformation of nanomaterials is the difficulty of the current research. To this end, Professor Lou, Professor Li Baojun, Associate Professor Li Juan, etc. successfully constructed tungsten nanocrystones with an surface-to-elevated resonance effect in the range of via-infrared light through electron-doping semiconductors, and used its bureau to use its bureau The collaborative role of the domain field enhancement and the light thermal effect realizes the selective enhancement of the green fluorescence of nanoparticles in the upper conversion of nanoparticles. Studies have found that under the triggering of near -infrared light, the composite structure of tungsten acid 铋/up conversion nanoparticles can achieve dual function of cancer cell biological imaging and light therapy at the same time. This work provides new ideas for biomedical applications for semiconductor waiting for 导 该.

Professor Xue Can of Nanyang University of Technology in Singapore and Professor Zhang Haipeng, the First Basic Medical College of Jinan University, also made important contributions to this work.

Undergraduate Sun Chengbo, Liu Chunyan and Li Xiaoshi

Get the third national college student chemistry experiment

The first prize of the National Finals of Innovation Design Competition

Recently, the 3rd National College Student Chemistry Experimental Innovation Design Competition, hosted by the National Experimental Teaching Demonstration Center of the Ministry of Chemistry and the Ministry of Education, has successfully concluded. Sun Chengbo, Liu Chunyan, and Li Xiaochi of the School of Chemistry and Materials, the 2020 undergraduate students, won the first prize of the National Finals. Feng Pengju and Liao Xiaojian served as the instructor. This is the first prize for the second consecutive year after the college undergraduate won the first prize of the event last year. This competition has a total of 410 universities across the country, with more than 900 teams in the preliminary round, and has been held in the northeast, North China, East China, Central China, Northwest, Southwest, and South China. Our undergraduate students performed well in the preliminary round. They won the first prize of the competition area, and the results ranked among the top 15%of the competition area to enter the national finals.

Undergraduate Wu Guangheng

Paper Papers of the TOP Journal of the Chinese Academy of Sciences 2

近日,信息科学技术学院/网络空间安全学院师生在中科院2区TOP期刊《Engineering Applications of Artificial Intelligence》在线发表了题为“BLCov: A Novel Collaborative-competitive Broad Learning System for COVID-19 Detection from Radiology Images "Research papers.

Inspired by the effectiveness of the coordinated competition representation (CCR) mechanism, the authors first proposed a novel automatic encoder (CCRAE) based on collaborative competition, and then CCRAE first proposed the collaborative competition width learning system (CCBLS) for the first time to in order Solving the above problems, and for the first time, CCBLS is used to automatically detect the medical COVID-19. The proposed method is used to extract features from CT scanning or chest X-ray image, and then use these features to CCBLS for COVID-19 detection. This method introduces the coordinated competition representation mechanism to BLS, making full use of the synergy and competition representation of the original data, and achieves better features. Compared with previous methods, the method can achieve better detection performance. The result shows that the wide learning system after integrating the coordinated competition mechanism has a wide range of application prospects in multi -disciplinary cross -fields such as artificial intelligence and medicine.

The first author of the paper was Wu Guangheng, a 2019 undergraduate student, and the author of the communications was Duan Junwei. The research results have been supported by the National Key R & D Plan "Active Health and Aging Science and Technology Copper", the support of the projects of the Natural Science Foundation of the Guangdong Provincial Basic and Application Fund Natural Science Foundation, and the key laboratory of the China Medicine Informatization Laboratory of TCM Informatization of Guangdong Province Essence

Original link:

https://www.sciencedirect.com/science/article/pii/s0952197622003591

The ocean of knowledge is vast

The exploration is endless

Jinan teachers and students always

With the motherland, climb the peak bravely

Seeking truth and pragmatism, integrated wisdom research

Go to explore more unknown and possibilities

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