The first case in China!Cut the normal skin and then cultivate in vitro. The Changhai Hospital takes 1 month to repair 100%of patients with large area burns

Recently, the first affiliated hospital (Shanghai Changhai Hospital) of the Naval Military Medical University (Shanghai Changhai Hospital) burning surgery for the first time in China has carried out "autologous epidermal cell transplantation technology" to repair a large area of ​​burns and achieved success.

This technology is the academician of the Chinese Academy of Engineering and Professor of the Burning Department of Changhai Hospital. It will continue to carry out deeper research in more fields and explore new directions for large -scale deep burns.

A few days ago, the patient, Ms. Chen, was burned by a fire caused by the gas explosion during the cooking process. The full body burns reached 80%, and she needed to be surgery to save her life.

According to the previous treatment plan, the normal skin on the patient needs to be cut, cut it into a small leather tablet or pull the skin to the net before being transplanted to repair the wound. Because there are fewer normal skin left by Ms. Chen, they need to repeatedly cut the number of sections to meet the needs. Moreover, the gaps in the leather sheet after surgery are large, the fusion time is long, and the recovery is slow.

After the demonstration of the team of Burning of Ko Xiao Shi, it was decided to use the "autologous epidermal cell transplantation technology" to treat Ms. Chen. The surgery team cut a normal skin of 5 square centimeters from other parts of Ms. Chen. After about 2 weeks of in vitro culture, the autologous epidermal cells were expanded to more than 4,000 times of the original number, and a transparent autologous epidermal cell film was finally formed.

The surgery team combined this film with conventional leather portal transplantation technology to treat Ms. Chen. In just one month, Ms. Chen's burns's wound repair rate reached 100%, and they could walk normally. Patients need 2-3 months to recover.

"I can recover so quickly, thanks to the careful treatment of doctors and nurses of Changhai Hospital, and even more than to the development of medical technology. I feel very lucky, thank you for the medical staff of Changhai Burning Department!" Before discharged, Ms. Chen excitedly excitedly Say.

▲ Cultivated autologous epidermal cell membrane tablets

According to Professor Xiao Shichu, the technology can be successfully applied to clinical clinical is the period of more than 20 years of research on skin tissue engineering research. -10000 times, so that the source is constantly providing the source of the patient. Related topics have been supported by the National Key R & D Plan and the 173 Program key projects, and have published more than 20 SCI papers. According to clinical data, patients with deep burns are more than 30%of patients can benefit from it, which can not only save limited autologous skin sources, but also accelerate wound healing and reduce scar hyperplasia.

Author: Li Chenzhen

Edit: Li Chenzhen

Editor in charge: Tang Wenjia

*Wenhui exclusive manuscript, please indicate the source for reprinting.

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