World lymphoma day: 1 person is diagnosed every 5 minutes. How to achieve early "healing"?

The 21st Century Business Herald reporter Ji Yuanyuan reported on September 15th to the World Lympoloma Publicity Day on September 15. In China, lymphoma is one of the most common malignant tumors, with about 100,000 new patients per year. In recent years, lymphoma innovation treatment has developed rapidly, and the survival rate of five years of disease -free disease has continued to improve. More and more lymphoma patients are looking forward to returning to society and embrace a better life. However, the employment of patients with lymphoma patients is not optimistic. The survey of the "Book of Survival Report in lymphoma patients in 2019" shows that the general unemployment rate of lymphoma patients is 56%due to illness, and the labor force of young people is particularly serious.

As the world of lymphoma is coming, in order to further increase the public's attention to patients with lymphoma, Professor Zhao Weilai, deputy dean of Ruijin Hospital, told the 21st Century Business Herald that one of the very important factor of the increase in the burden on lymphoma disease is that lymphoma incidence is the incidence of lymphoma. There are many reasons for the incidence of lymphoma, including the infection of the virus, the environmental pollution, and the aging of the population. After the incidence of lymphoma increases, there are more patients with lymphoma who need to treat, so the burden on the disease will be relatively high.

"At the same time, the incidence of lymphoma will increase with age. This also requires that we have standardized treatment, continuously updated clinical treatment plans, and integrate with international innovation therapy to improve the efficacy." Professor Zhao Weilai said.

Patients with lymphoma need to be individualized

In China, lymphoma is one of the most common malignant tumors. The incidence of lymphoma in my country is about 668/100,000, and about 100,000 new lymphoma patients per year. This means that there are 1 person every 5 minutes. It is diagnosed as lymphoma, and the incidence is still increased year by year.

In June 2018, the Department of Hematology of Ruijin Hospital took a doctor of a patient who had just given birth to a baby (a pseudonym). The result of the pathological examination allowed all the doctors of the hematology department to take a deep breath. This type of lymphoma is rare, and many doctors bluntly say: this is the first patient encountered since the medical. "Patients and their families are often looking forward to a false result, but reality will always look forward to shattering. On the day of face -to -face consultation, I saw the teacher's effort to control his expression and comforted it. You were admitted to the hospital. Later, that day, the department and the academician called a long phone, until the electricity of the mobile phone was almost exhausted, "said Zhang Mochen, a hematologist of Ruijin Hospital.

According to the pathological characteristics of lymphoma cells, it is mainly divided into Hodgkin lymphoma (HL) and non -Hodgkin lymphoma (NHL). Hodgkin lymphoma (HL) has a low incidence, accounting for about 8.54%of all lymphoma. The prognosis is good and the cure rate is high. Most Hodgkin lymphoma (HL) patients survived for 5 years> 85-95%. The incidence of non -Hodgkin lymphoma (NHL) accounts for about 87%of all lymphoma. Among the patients who are not Hodgkin lymphoma (NHL), the most proportion is patients with large B -cell lymphoma (DLBCL). And ALK-positive+diffuse large B cell lymphoma is a rare CD20-invasive mature B cell tumor. It has high-level histological characteristics and the differentiation of the mother cells. The prognosis is poor.

To this end, the hospital integrates the forces of the whole department to discuss the treatment plan for Xiaomeng. What impressed Dr. Zhang Mochen was most impressive that Xiao Meng suffered a sudden blood pressure and heart rate drop when he started chemotherapy. "I was also one of the doctors who participated in the rescue at the time. In that dying Rally, the only thing I remembered was to keep telling myself, stick to it for a while, and persist for a while to help the patient seize the light of the raw." Fortunately Multiple rounds of treatment, Xiao Meng was successfully discharged.

Zhao Weilai introduced that in the treatment of lymphoma, the hospital will actively establish a full -process management of overall treatment. For example, for the first time for patients to go to the hospital for treatment, the doctor will formulate an individualized and standardized treatment plan based on the patient's pathology and molecular characteristics and clinical characteristics. In this way, some patients will be arranged to the day ward, and some patients will be arranged to the consortium hospital for treatment in accordance with the standardized plan.

"If the patient's condition is good, it has been managed in the daytime ward or consortium hospital. If the patient's condition is repeated, he will return to the general hospital to adopt a new treatment plan." Zhao Wei introduced After the construction of the center, there are many new clinical studies that can provide more and better treatment plans for patients with difficulty recurrence or high -risk, so that patients can be fully managed by patients, which can enable more patients to enter the hospital's treatment framework In the system.

"We are also constantly improving. If the day ward and medical consortium of the Ruijin General Hospital is formulated, the traditional treatment plan with the Ruijin team as the core, on the one hand, there are standardized treatment, on the other hand The research of innovative industry -university -research work has the opportunity to treat more patients. Medical resources are limited, but the way we think should be infinite. "Zhao Wei said.

It is also due to the development of medical technology and the development of the original research and innovation medicine that the survival rate of lymphoma for five years has continued to increase. According to the survey, the survival rate of Chinese lymphoma patients in five years is nearly 38%, while in relatively developed areas such as Beishangguang, the cure rate of lymphoma can reach 60%-70%.

"At present at Ruijin Hospital, the five -year -old survival rate of lymphoma is increasing year by year, and the number of 'graduates' has also increased. As witnesses, our entire team is very pleased." Zhao Weilai said that we look forward to more innovative treatment treatment The emergence of the scheme can help lymphoma's disease -free survival rate of more than 90%in five years, and finally achieved healing goals. There are still pain points behind the standardized treatment

From the original research and innovative drugs of Lifen, to today's Opuzumab and Vitamin Mipidumoplasty, breakthrough innovative drugs have continued to innovate lymphoma treatment patterns. At the market level, according to public data, since 2016, my country's lymphoma drug market has grown steadily, from 14.07 billion yuan to 16.07 billion yuan in 2019, with a compound annual growth rate of 4.53%; China's lymphoma drug industry in 2020 The market size reached 16.97 billion yuan, a year -on -year increase of 5.6%. With the continuous growth of my country's lymphoma drug market, it is expected that the market size of the Chinese lymphoma drug industry will reach 22.16 billion yuan by 2025.

At the same time, in response to the innovative pharmaceutical industry, my country's policies are favorable, helping the technological research and development investment in lymphoma drug companies increase, and improve the customization and supervision of industry rules and regulations. In addition, due to the high economic burden of lymphoma, the admission of Chinese medical insurance drugs will reduce the price of lymphoma drugs, promote the industry to move towards civilianization, and reduce the economic burden of patients. It is also due to this that lymphoma therapy is constantly developing in the direction of precision.

"In recent years, the doctor can choose a targeted medicine related to the onset and efficacy of the patient through the molecular detection method. On the one hand, it can better improve the efficacy, and on the other hand I declared a new medical testing method to the National Bureau. I hope that this method can be promoted to the whole country in the future, so that the treatment team of pathological teachers and lymphoma across the country can be tested, so that patients across the country will have the opportunity to choose a more suitable targeted drug Chemotherapy, reduce the use of chemotherapy, and improve the efficacy of the treatment. "Zhao Weilai said that there are more than 100 types of lymphoma, and each type has a special treatment plan, which also means that each patient needs to be based on different clinical and molecular pathological analysis analysis , Choose more reasonable individualized treatment solutions.

For patients with lymphoma, recovery after illness, returning to society has also become a key issue. Gu Hongfei, the founder of lymphoma House, introduced that after receiving standardized treatment, there are many pain points that need to be paid attention to. For example, returning to the workplace and recovery work ability is the first step in the return of most lymphoma patients, but the employment of this group at the moment Not to be optimistic, many rehabilitation patients who are in the middle of their adolescents have been rejected because of lymphoma. In fact, most lymphoma recovery can participate in social labor like normal people.

According to the "White Paper of the Survival Report of lymphoma patients in 2019", lymphoma has a strong negative effect on the aging labor force, especially for young people's labor, up to 93.5%of young people (18-35 years old) Reading; 70%of the middle-aged leisure patients (35-60 years old), 70%of them cannot work or have to retire in advance due to illness. At the same time, more than 90%of the lymphoma patients who have stopped salary, dropped out of school, and lost laborers are caused by illness. Most patients who are unemployed/should be used at home or cook housework are also caused by lymphoma.

"There are many patients with lymphoma not only return to life, but also should return to the state of work, study, and living status before illness. Therefore, we encourage patients to re -raising the sails of life in the case of overall treatment. At the same time, we also call on the whole society to care about supporting lymphoma patients and look at them with the eyes of friends, loved ones, and colleagues. "Zhao Wei said.

Of course, in addition to focusing on helping patients out of the haze of the disease, regaining confidence and rebuilding a better life, for the public, in daily life, regular physical examinations are needed to prevent the disease from deteriorating.

Zhao Wei went to suggest that first, aging and tumors are closely related. The elderly are high -incidence of tumors, so they should be physical examinations;

Secondly, do not panic if there are symptoms of lymphoma. It is not to say that all lymph nodes are lymphoma. If there is any timely, close follow -up. Consider the possibility of lymphoma;

In addition, lymphoma will also occur in other parts of the body. If other parts are found to be discomfort, do not taboo diseases and do medical diagnosis. Only pathological examinations can only achieve precise diagnosis.

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