New research helps reduce acute kidney injury related to cardiac surgery

Xinhua News Agency, Sydney, September 13 (Reporter Hao Yalin) A new study involved in Australian scientists found that the level of protein in the blood is related to the risk of some patients suffering from acute renal injuries after heart surgery, and targeted prevention prevention Means to help reduce the occurrence of complications.

The study was jointly carried out by Australian Peter Dort infection and immunomotive research institutes, University of Melbourne, and South France. Related papers have been published in the "Basic Basis of the American Heart Society: Transformation Science".

According to the Institute of Peter Dort infection and immune, after receiving heart surgery, 20%to 30%of patients will have acute kidney damage, and patients who receive blood transfusion during surgery are more likely to have acute kidney damage. But for a long time, clinicians have not yet known the specific causes of acute kidney injury related to cardiac surgery.

In this study, the team discovered that if the patient entered the blood had a higher level of medulical -related protein 14 (MRP_14), they would be more likely to have acute kidney injury. Experimental data shows that MRP_14 can cause an immune cell in the human body -neutral granulocyte accumulation. The "swallowing" effect of neutral granulocytes will cause damage to the kidneys.

Researchers believe that the level of MRP_14 in the blood before blood transfusion may try to reduce its number or reduce its activity, which may prevent patients with acute kidney damage.

Researchers said the study helps to better understand and treat acute kidney damage caused by cardiac surgery. On this basis, researchers have started to study further, such as using new blood transfusion methods to make patients have a better prognosis.

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