The world's first!Dr. Tongji obtained 12 patents, but inspired by watching people by watching people by the river ...
Author:Changjiang Daily Time:2022.09.10
The Yangtze River Daily Da Wuhan Client September 9th (Reporter Jiang Mengqing Correspondent Li Yunxi) "We have been running with others, can we explore a leading innovative technology to the forefront."
Professor Wei Xiang, Director of Cardiology of Tongji Hospital affiliated to Huazhong University of Science and Technology, and the world's first "myocardial cutting system" in the world, overcome a major fortress in the world of heart disease, and found a new concept and surgery for hypertrophic obstructive myocardiasis surgery surgery. Path: Do not open the chest and the heart constantly. In physiological state, minimally invasive incisions are precisely removed.
This technology has been used to treat children's fat heart disease for the first time. It is 12.8 grams of "weight loss" for 14 -year -old Lele heart, far exceeding the heavy myocardial weight that can be removed by traditional chest opening surgery, and has obtained a total of 12 patent inventions. The inspiration at the beginning of the research and development stems from the main doctor Wei Xiang to watch people cut pineapple by the river beach, and the inspiration obtained.
The 14 -year -old girl was studying online in the ward after music and was about to be discharged. (The second right is Professor Wei Xiang)
Effectively imitate the principle of pineapple and develop the "weight loss artifact" of the heart
The hypertrophic obstructive myocardiasis is a congenital heart disease that is concealed. Many people may have no abnormal heart when they are born. As they grow, the heart will "gain weight" quickly as hormone. By adolescence or adults In the early days, the heart was more than twice as thick as the same age. When the event, it was easy to cause chest pain and chest tightness. It was the main reason for the sudden death of teenagers and athletes.
Based on the incidence, more than 2 million people in the country suffer from the disease, but less than 1,000 patients undergoing surgery each year.
"There are too few doctors who can perform surgery, and there are not many patients who are willing to perform chest surgery." Wei Xiang told reporters that traditional surgery needs to be sawn for about 20 cm in the sternum, surgery under the heart stopping and in vitro circulation. High, the surgical vision is limited, the risk is large, and the recovery is slow. Most patients look forward to it after listening to it, and choose to take the drug conservative treatment, but the drug can only temporarily relieve the symptoms and cannot fundamentally solve the "obstruction".
The patient's problem is the biggest driving force for doctors to do scientific research. For 25 years, Wei Xiang has been trying to explore a new surgical and equipment to improve the treatment rate of patients with fat heart disease.
Occasionally, "the stone of his mountain" made him inspired. One Sunday in March 2018, Wei Xiang took a walk at the river beach in Wuhan and was attracted by the action of cutting pineapple by the fruit merchants. pull out.
Wei Xiang thought: "Can you follow the principle of cutting pineapple and make a surgical equipment with a rotary cut function, change the path of entered the heart from the heart after opening the chest. Inside the body? "
If this bold idea becomes true, myocardial surgery will no longer be a "peeping leopard in the tube". It can be seen at a glance in the ultrasonic image. It can more precisely remove the thick myocardium, trauma, fast recovery, and good efficacy.
Thinking of the domestic ultrasound doctor invented the basic support of the spikes, Wei Xiang was so excited for feasibility. He bought a knife and planer cutting pineapple, and ran home to start drawing drafts. In the second week of Saturday, he went to Beijing alone to communicate with the factory and process it into real equipment according to the drawings.
After receiving the equipment returned, Wei Xiang and the team couldn't wait to put it into practice and began to exercise in the pork heart. The ideal is full, and many suspicious problems are encountered during the landing process.
After the elbow of the first version of the design enters the pig heart, the cut tissue quickly flows into the head with the blood invested, and the surgery cannot continue; the outer mechanical outer layer is made of a strong pseudo -shadow, causing interference to B -ultrasound imaging. Native
Wei Xiang and the team continuously improved the new problems in the experiment and technical research. The equipment design was improved according to the specific surgery requirements: change the elbow to the straight head, put on the "stealth jacket" (plus coating) for the equipment ... After 3, 3 After the annual trial production, experiments, and improvement, the final version of the fixed -type prototype was formed after the iteration of the prototype iteration of the prototype of 7 times.
It is reported that this set of cardiac rotation system contains myocardial rotation and clinical equipment, all of which are the world's first. In 2018, it was supported by the Ministry of Science and Technology's "Special R & D Project for Digital Diagnosis and Treatment". In the past three years, 12 patents including national invention patents and US invention patents have been obtained.
Professor Wei Xiang and his team performed a minimally invasive ventricular dispery surgery for the patient. (The second right is Professor Wei Xiang)
From animals to humans, for truly application to clinical adventure
Based on a certain level of technical level and research results, whether doctors are willing to take more work and greater risks.
Although the live pig heart experiment has achieved empirical effects, from animals to humans, it is still a major challenge to the clinical clinic, and it is also a test of the courage of developers.
Pig heart resection can only be cut, usually only 0.5 grams of tissue; and patients who need to be operated, the cut tissue is generally 5-10 grams, which is 10-20 times that of pig heart experiments, and the equipment needs to be multiple times. Enter the heart.
Faced with the differences and potential risks of clinical and experimental operations, Wei Xiang admitted that he had hesitated to give up, but he eventually affected the pressure and applied for clinical experiments.
In February this year, the first patient had the first patient who dared to "eat crabs". A 28 -year -old adult man, with full communication and preparation of surgery, Wei Xiang's first sword for him to perform the first micro -invasive room for the heart of the heart of the heart. Divide the heart muscle resection surgery. "Seeing the first patient with a sober tube 1 hour after surgery, and communicating with his family normally, the team and I were extremely excited. More patients with myocardial disease had a new choice." Also give Wei Xiang a video of his fitness. According to Wei Xiang, before the invention of this technology, there are not many surgical surgery of hypertrophic obstructive myocardiasis every year. Tongji Hospital applied this operation and equipment. 40 cases have been carried out in half a year this year. %. The new minimally invasive ventricular corrosion of the cardiac rotation surgery is suitable for almost all types of hypertrophic obstructive myocardiasis. It has unique advantages in treating children and adolescent hypertrophic obstructive myocardiac diseases. The heart structure can also be more accurate to remove the hypertrophy.
A week ago, he was happy to have a 14 -year -old girl with severe congenital hypertrophy obstruction cardiomyopathy. With the heart that keeps jumping and opened the chest, the heart obstruction was smoothly lifted. The surgery time was less than two hours. Hou Lele broke away from the ventilator and got out of bed the next day.
Generally, the application scope of new technologies is limited to age patients over 18 years of age. Considering that some children patients may wait until the age of 18, Wei Xiang applied for clinical trial ethics for children, lowered the age of surgery, so that children with needy fat heart disease can be treated as soon as possible.
"The minimally invasive cardiac rotation is in line with the development trend of precision medical care and the concept of modern surgery in the future. Regional and hospitals have achieved the overtaking number of traditional chest cutting hypertrophic myocardial surgery, bringing the gospel to more patients. "Wei Xiang said.
【Edit: Wang Rongfei】
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