"Chinese Medicine Magazine" published an article on risk assessment, safe medication and scientific supervision of mosenolic acid traditional Chinese medicine

"Chinese Medicine Magazine" in the 14th cover article in 2022, published the "On the Risk of Mattin Acid Acid Academic Acid Acid Academic Acid Academic Acid Academy's Risks, Honorary President of Tianjin University of Traditional Chinese Medicine, an academician of the Chinese Academy of Engineering, and a researcher at the Chinese Academy of Traditional Chinese Medicine, and a researcher at the Chinese Academy of Traditional Chinese Medicine Sciences Institute of Traditional Chinese Medicine. Evaluation, safe medication and scientific supervision -different toxic acids of aristolochic acid, prosecution of aristolic acid Ⅰ/Ⅱ is the key ".

According to reports, there are many types of aristolochic acid compounds (AAAS), and the structure types are mainly divided into aristoloLactams (ALS) according to the structure types. Studies have shown that the types of AAAS are different, and the toxicity of its compounds is large: AA-Ⅰ has strong kidney toxicity and carcinogenicity, AA-Ⅱ toxicity is lower than AA-Ⅰ, while AA-IVA and AA-IA have no obvious toxicity. The types and contents of the AAAS contained in different varieties of aristolochia are very different. Some varieties such as asarum and Tianxian Teng include AAAS (such as AA-IVA) without obvious toxicity. The AAAS content in the compound preparation is related to the proportion of the medicine and the preparation process. In some preparations, the AA-Ⅰ content is very low or cannot be measured. Therefore, the author proposes that "different types of AaaS and different toxicity, not all AAAs have renal toxicity and carcinogenicity. The toxicity of AAAS Chinese medicine should not be generalized, and prosecution of AA-Ⅰ and AA-Ⅱ is the key." This article proposes that "for AAAS traditional Chinese medicine, it should not be scrapped due to choking, and the research and analysis of the types and content of AAAS in Chinese medicine should be strengthened, and the research of toxicology is formulated, and the limited standards of AA-Ⅰ and AA-Ⅱ should be formulated.

"Chinese Medicine Magazine" is a comprehensive Chinese medicine academic journal organized by the Chinese Science and Technology Association, sponsored by the Chinese Academy of Pharmaceuticals, and hosted by the Institute of Traditional Chinese Medicine of the Chinese Academy of Chinese Medicine. It was published in July 1955. It reflects the latest progress and research dynamics in the field of Chinese medicine and natural medicines in my country. It is one of the exchange platforms for the highest scientific and academic level of traditional Chinese medicine. Obtained the "China Science and Technology Journal Excellent Action Plan Construction Project-Echelon Journal Category". He was selected as the T1 area of ​​the Chinese Medicine Science and Technology Journal Tie, ranked first in the list of 11 T1 levels; Chinese core journals; Chinese science and technology core journals; Chinese science citation database (CSCD core version) Q1; Chinese academic journal (online version) source journal Essence

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