Nine -valent HPV vaccine expansion!9 to 45 years old can be played

On the evening of August 30, the website of the State Drug Administration showed that the indication of Merida's nine -valent papilloma virus vaccine (brewing yeast) (hereinafter referred to as the nine -valent HPV vaccine) was expanded, and the applicable population expanded to a 9 to 45 -year -old female vaccination.

On the same day, Merck also released news, confirming that the new indication of the Nine -Valental HPV vaccine was approved by the State Drug Administration. Subsequently, the "HPV nine -valent vaccine expanded to 9 to 45 years old" quickly appeared on Weibo hot search.

Nine -valent HPV vaccine expands to 45 years old

Cervical cancer is one of the common gynecological malignant tumors. In 2021, ICO/IARC's HPV and related diseases in China show that in 2020, among women 15 to 44 in China, the incidence and mortality rate of cervical cancer ranks third in female tumors.

The HPV vaccine is divided into two -valent, four -valent, and nine valence according to the virus subtypes covered by the vaccine. The age range of each vaccine is slightly different. Among them, the applicable age of the binary HPV vaccine is 9 to 45 years, covering HPV16 and HPV18. The applied age of quadrilateral HPV vaccines is 20 to 45 years old, covering HPV6, HPV11, HPV16, and HPV18. Nine -valent HPV vaccine covers HPV6, HPV11, HPV16, HPV18, HPV31, HPV33, HPV45, HPV52, and HPV58. The previous applicable age was 16 to 26 years old. Many women have been forced to give up the nine -valent HPV vaccine due to their age.

After being approved, the four -valent and nine -valent HPV vaccine of Meroshadong were 9 to 45 years old women. In 2018, Merck's nine -valent HPV vaccine was approved in China, but was only approved for vaccination for women aged 16 to 26.

Tian Anna, a senior vice president of Global Global and President of Merhado, said that the expansion of the applied age of the nine -valent HPV vaccine shows that the Chinese government's determination to accelerate the elimination of cervical cancer. Hyd sex.

Nine -valent HPV vaccine is still "hard to find"

At present, the HPV vaccine, which has been approved by my country, includes imported Merosa East Four Valentine Vaccine "Jiada Xiu", Nine -Valental Valles "Jiada Xiu 9"; Grandulosk's two -valent vaccine "Herry"; and domestic 10,000 Thai creature's binary vaccine "Xin Kening" and the binary vaccine of Watson Biological "Wozawa". At present, the nine -valent HPV vaccine is the highest -priced vaccine that can be used to protect HPV viruses on the market. It is also the most sought after vaccine.

However, the penetration rate of the nine -valent HPV vaccine still cannot meet the huge market demand, showing "one shot". Since being approved in China in 2018, Meridon has increased the supply of nine -valent HPV vaccines every year. Zhifei Bio is a domestic agent of the Merck HPV vaccine. Its semi -annual report in 2022 shows that from January to June 2022, the number of nine -valent HPV vaccines was issued 9.2987 million, an increase of 379.34%year -on -year.

Merck also disclosed in the half -year report of 2022. In the first six months of this year, China's sales increased by 87%year -on -year to $ 2.57 billion. Merhadon specifically stated that in recent quarters, the demand for Jiadaxiu in the Chinese market has continued to be high, and it has continuously promoted the company's Chinese business expansion.

Many domestic nine -valent HPV vaccines enter the third phase of the clinical clinical

Except for Merhado, the drug clinical trial registration and information publicity platform shows that in China, 5 companies including Kangle Guardian Wantai Biology, Boyi Biology, Ruico Bio, and Zerun Bio (Watson Biological Subsidies) are underway. Nine -valent HPV vaccine's third phase of clinical trials. Except for Zirun Bio, the upper limit of the clinical trials registered by the remaining four companies are 45 years.

On the morning of August 31, Wantai Biological told reporters that the company's nine -valent HPV vaccine and Merck's nine -valent HPV vaccine have completed the clinical trial site and specimen testing of clinical trials. The bridge is completed in clinical trials.

Liu Jun, deputy chief physician of the Obstetrics and Gynecology Department of Beijing Chaoyang Hospital affiliated to the Capital Medical University, said that it is not recommended to blindly pursue the vaccination of the nine -valent HPV vaccine, and it is also recommended to vaccinate the vaccine in time when he is age.Liu Jun said that the two -price and quadrilateral HP vaccine can also play a good prevention effect. It is not recommended to wait for the better price to wait for the high -priced vaccine in order to increase the scope of protection (source: Beijing Daily, People's Daily)

Edit: Liu Tianyuan

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