Imported nine -valent HPV vaccines Domestic applicable population expanded.

Chinanews.com, August 31st (China Singapore Finance reporter Zhang Ni) On the 30th, "Merck China" WeChat released a news that its nine -valent papilloma virus vaccine (nine -valent HPV vaccine) has been obtained by China The State Drug Administration approved that the approval marked the expansion of Merck's nine-valent HPV vaccine in China to 9-45 years old.

As soon as the news came out, it attracted great attention from the outside world. Merhadon was approved to be listed in China in 2018, but at that time, his applicable age group was 16-26 years old, and "unable to vaccinate" has always been a pain point for many women.

So the age range of vaccination is widened, can people who have previously vaccinated two -price or four -valent vaccine, can the nine -valent vaccine be vaccinated again? What is the impact after vaccination?

Merhado Chinese official micro screenshot

What are the effects of nine -valent HPV vaccine?

What is the role of the nine -valent HPV vaccine? According to the information published by the China Disease Prevention and Control Center, the vaccine is suitable for the following infection or disease caused by the HPV type contained in the vaccine:

First, infections caused by HPV6, type 11, 16, 18, type 31, 33, 45, 52, 58, 58

Second, the above nine types of HPV types are caused by cancer or typical lesions, including cervical epithelial tumor -like lesions (CIN) level 2/3, cervical original adenocarcinoma (AIS), and cervical epithelial tumor -like lesions (CIN )Level 1;

Third, cervical cancer caused by HPV16, type 18, 31, 33, type 45, 52, and 58 types.

What are the main differences between the two -valent, four -valent and nine -valent vaccine, and how to choose?

The most important difference between the second price, four -valent, and nine -valent HPV vaccine is that it contains HPV types different, two -valent HPV vaccine, containing HPV16 and type 18 virus L1 protein. Protein, nine -valent HPV contains 6, 11, 16, 18, 31, 33, 45, 52, and 58 virus L1 protein.

However, all three vaccines can be targeted at the above high -risk HPVs to prevent HPV -related diseases. They can combat HPV16 and type 18 infections, and the effect is very significant. Compared with two -valent HPV vaccine, the quadrum HPV vaccine can also prevent genital warts caused by HPV6 and 11. The nine -valent HPV vaccine will increase the proportion of cervical cancer from 70%to 90%.

Photo by Li Chun, a reporter from Xinhe in the data map

Can you still get nine -valent after vaccination after vaccination?

At present, people are most concerned about the two -valent and tetal vaccine that have been vaccinated before. Can they continue to vaccinate the nine -valent vaccine in the future? Is there necessary?

In response, China Cep use has stated that there is no clinical data that supports the use of nine -valent HPV vaccine and other HPV vaccines. The World Health Organization has no preference for HPV vaccine stance documents.

From the perspective of public sanitation, the two -valent, quadrilateral and nine -valent vaccine can provide considerable immunogenicity and protection effects in preventing cervical cancer (mainly caused by HPV16 and HPV18). According to the existing conditions, three HPVs are vaccinated by three HPVs Any type of vaccine is okay.

According to the nine -valent HPV vaccine instructions, if someone is vaccinated with 3 doses and tetravalent HPV vaccines, and the nine -valent HPV vaccine also wants to take over the nine -valent HPV vaccine, it can be vaccinated at least 12 months apart, and the inoculation agent is 3 doses.

Can a two -price or four -valent vaccine in vaccination of one or two stitches be changed to a nine -valent vaccine?

China Disease Control has previously introduced that in 2016, the U.S. Immune Strategy Implementation Consultation Committee (ACIP) recommends that if a four -price or binary HPV vaccine starts to take over the process, the remaining agents can be replaced with a nine -valent HPV vaccine to complete the entire vaccination procedure, but According to the World Health Organization's 2017 HPV vaccine position document, the safety, immune or effect of the three HPV vaccines is very limited. These vaccines are different in terms of characteristics, components, and indications. In addition, the quadrilateral and nine -valent HPV vaccine instructions also specifically pointed out that there is no clinical data that supports the exchange of nine -valent HPV vaccines and other HPV vaccines.

Therefore, in areas that can choose a variety of vaccines, they should strive to achieve a unified vaccination procedure and use the same vaccine for each dose.

Data map: HPV virus model Wang Dongming was taken by Wang Dongming

Will not get the disease caused by HPV?

No vaccine can play a 100%protection effect.

All HPV vaccines 16 and 18 (about 70%) can provide high -level protection. HPV vaccines also provide some cross protection for some non -vaccine types.

The nine -valent HPV vaccine will increase the proportion of cervical cancer from 70%to 90%, but because the failure of all high -risk HPV types is not overwritten, the nine -valent HPV vaccine cannot prevent 100%of the infection or disease caused by HPV. The post -cervical cancer screening should be carried out as usual.

Who is not suitable for vaccination with a nine -valent HPV vaccine?

For those with any active ingredients or auxiliary materials in HPV vaccines, those with severe allergies are contraindicated. Those who have allergic reaction symptoms after vaccination shall not be vaccinated again. (Finish)

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