Laoyou Miscellaneous Talk 135: The thinking habits of developing critical reading are very important 丨 Express: Shanghai pilot artificial intelligence medical device; baby swallowing batteries cause gastric mucosa erosion;

Author:Medical newspaper Time:2022.08.27

So far, research on methodology has revealed that the shortcomings of medical literature in research and implementation and reporting are common. Based on the proof of internationally renowned research cases, the results of the research published in the well -known journal will not accept the results of the well -known journals, which will lead to serious errors and resources waste. Method studies have shown that most of the reports in biomedical literature are observation research. Observation research reports are usually poor. Most of the observation research results published are wrong. Even those real discovery, most of them are mostly discovered, most of which The result is also exaggerated, and the result cannot be repeatedly a common problem in biomedical and behavioral science. The use of large -scale management databases for research, usually accurate but wrong results. In fact, 85%of the annual research investment is wasted.

There are 12 random trials to verify the conclusions of 52 observation research. The intervention measures include diet, vitamins and minerals. However, the results of no observation research report can be confirmed. Ironically, random experiments have found that the results of its results are opposite to 10%observation results. It was recommended that the use of metropolis by menopause can prevent measures such as heart disease, intake of cellulose and folic acid, which can prevent random control tests such as random control tests. There are more than 1,800 reports in the PUBMED database to study the relationship between oral contraceptives and coagulation. After paying a huge unnecessary effort, people finally reached a consensus: without any coagulation test, which women can suffer from rare serious serious serious serious serious serious serious serious serious serious serious serious serious serious serious serious serious severe serious serious serious serious severe severe serious. Incidents, the regulatory agencies should stop conducting coagulation research that cannot be conducted in any prediction. In a random trial of fluoride treatment of osteoporosis, the fluoride compared with the placebo and observed the bone density as expected by 35%.

However, the contradiction is that the spine and non -vertebral fracture of those who use fluoride subjects increased, and the bones became more dense, but the bone density measurement was only a characteristic of bone health. Not the quality of bone. Multi -drug resistance tuberculosis is a fatal infection, and the demand for new therapy is very urgent. In 2012, the FDA of the United States approved a new type of drug Beidolin. This approval was based on the result of an alternative to an unknown unknown: Patient's phlegm culture tuberculosis from positive to negative. The approval of the drug is based on the two medium -sized test results of 47 and 161 patients. It has not passed the large -scale clinical trials, and the impact on sputum culture is not significant. Surprisingly, the disease mortality of the new drug treatment was increased by 5 times.

Medical literature is full of forgery discovery. Due to insufficient control over mixed control, smoking and suicide are mistakenly linked. Selective bias obtained incorrect conclusions related to the reduction of the risk of heart disease at the level of estrogen levels; cases with poor quality in comparison in comparison of quality of quality associated with breast cancer, coffee drinking and pancreatic cancer; Loss of breast cancer; pseudo -science leads to a delisting of safe and effective vomiting drugs widely used in pregnancy; inappropriate control groups, information bias, and mixed influence of non -controlled sexual transmission diseases, resulting in the 20th century 80 In the age of the United States, the internal palace -saving device was almost disappeared; the lack of control of mixed control caused researchers to think that oral contraceptives were related to pituitary tumors.

Another regrettable example that damages public health due to the error explanation of descriptive research is the issue of electronic monitoring of the fetus during the output process. More than 20 years ago, the decline in the introduction of fetal monitoring and perinatal mortality occurred. The time association made people think that the sustainable fetal heart rate monitoring can benefit. Based on the optimistic evaluation of the well -known obstetrician and gynecologist, this has not been scientifically reviewed expensive interference technology to bring a storm to production science. However, random control test shows that compared with conventional intermittent auscultation, electronic fetal monitoring has no continuous benefits to babies, which has increased surgical delivery significantly, causing harm to women.

The wise man pointed out that the highly respected risk factors have performed well in data mining articles cut into thin pieces. A danger of managing database research is "huge statistical significance". Due to the large sample volume, almost all weak associations have narrow confidence interval and impressive statistics. Big data can find no difference in significant differences. The trivial association has reached statistically significance, but there is no clinical significance. Due to the inaccurate diagnosis and the lack of control of potential mixed factors, these studies may be accurate, but they are not effective. Therefore, the greater the sample amount in clinical research is obviously wrong.

Newsletter

Ministry of Industry and Information Technology: Pilot area for the application of Shanghai as an artificial intelligence medical device unveiling list

On August 26, Ren Aiguang, deputy director of the Department of Science and Technology of the Ministry of Industry and Information Technology, said that it will jointly unveil the national pharmaceutical regulatory bureau to carry out the topic of the artificial intelligence medical device, and build the R & D-industry-application "fast lane", and will use Shanghai as the pilot area of unveiling results. (Source: Surging News)

1 -year -old baby swallowed 5 batteries and removed after 10 hours, causing gastric mucosa erosion

Recently, Shandong Liaocheng. A 1 -year -old boy swallowed 5 button batteries in the electric ear suction ware. Until the next day, the parents found one from the boy's vomit and sent the hospital urgently. After the doctor's examination, another battery was naturally discharged, and 3 batteries were stranded in the stomach and urgently "thunderstorm" through gastroscopy. At this time, the battery has been in the boy for more than 10 hours. "The child has severe gastric mucosa erosion, and there are a little ulcer. At present, the three button batteries have been successfully removed." (Source: Guizhou Transportation Broadcast) U.S. Northern Dakota Judge again put on the abortion ban again

On August 25, the Judge of North Dakota, USA, once again shelved the abortion ban in the state. The judge Bruce Romanic ruled that the "triggering law" of North Dakota's abortion ban should be kept on hold during the debate of the law. It is reported that the abortion ban in North Dakota was originally scheduled to take effect on the 26th. Romanic said that the abortion ban may cause incomparable damage to women and other related persons in the state. The preliminary prevention order issued on the 25th for the abortion ban is to maintain the status quo. (Source: CCTV News Client)

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