Lianzha 51 stitches did not say a word, 14 -year -old Wuhan boy donated the marrow to save his father

Author:Changjiang Daily Time:2022.08.24

The Yangtze River Daily Da Wuhan Client August 24th (Reporter Liu Xuan Correspondent Wu Lingling) In order to save the father who suffered from acute severe regenerative disabled anemia, 14 -year -old Wuhan boy Weng Fanglei endured the pain of pumping the marrow and took 51 stitches to extract. 1003 ml of bone marrow, just didn't say a word. "As long as I can save my dad, I am not afraid of pain!" This scene that made all medical staff moved in the bone marrow implantation of the bone marrow in Wuhan First Hospital on the 23rd.

"Dad, come on!" On the afternoon of August 24th, after 250 ml of peripheral blood stem cell suspension was collected again, Weng Fanglei deliberately detoured outside the transplant warehouse. Essence

On the 24th, Weng Fanglei collected peripheral blood stem cells. Correspondent Yiyu Mo Photo

Stem cell transplantation is required for men's emergencies

Weng Fanglei is a native of Huangpi District, Wuhan. His parents have worked in Hankou for many years. Since he has been in kindergarten, he has been studying beside him. After the beginning of the autumn, he was a third grade. The family lived peacefully because of his father Weng Haizhou's accident.

On July 8th, Weng Haizhou, who was working on the construction site, felt dizzy and panic, and could not be relieved after rest, and then went to the nearby hospital for treatment. Routine blood tests found abnormal blood elephants, indicating that severe anemia and extremely severe platelet counting is low. At the doctor's advice, the next day Weng Haizhou was admitted to Wuhan First Hospital (Wuhan Traditional Chinese and Western Medicine Integrated Hospital). After a series of specialized examinations, it was finally diagnosed with acute severe recycled disorders.

Cheng Hui, director of the Department of Hematology, Wuhan First Hospital, told Weng Haizhou that the recycled obstacle anemia is a bone marrow hematopoietic dysfunctional disease caused by various reasons. The cause is unknown and the onset is rapid. Bleeding and severe infection. If hematopoietic stem cell transplantation can be implemented as soon as possible, clinical cure and long -term survival can be obtained.

During the collection of peripheral blood stem cells on the 24th, Director Cheng Hui and Weng Fanglei communicated. Correspondent Yiyu Mo Photo

"As long as I can save my dad, I don't scare pain!"

However, suitable hematopoietic stem cells are difficult to find. Weng Haizhou has 4 brothers and sisters. Due to age and other reasons, there is no way to choose the compatriot supply of compatriots. The Chinese bone marrow storage was not screened to the appropriate supply.

Although Weng Haizhou's only son Weng Fanglei was only 14 years old, he weighed 85 kg of 1.68 meters tall and was similar to his father. He could donate bone marrow. When the son had long body, he was worried that the bone marrow would hurt the child's body. Weng Haizhou was hesitant. Tube bed doctor Cheng Ping told him that donating the marrow has nothing to do with age. As long as he weighs more than 40 kg, he can donate, and the child's bone marrow stem cells are very active, and it will return to normal soon after the donation. After detailed physical examination, matching, and physical condition evaluation, Weng Fanglei met the conditions for donating hematopoietic stem cells.

Regenerative disorders are caused by bone marrow hematopoietic failure. The richer the source of stem cells transplanted, the better the long -term effect of transplantation. Cheng Hui led the team to formulate transplantation solutions for Weng Haizhou: bone marrow stem cell transplantation+peripheral blood stem cell transplantation.

According to Cheng Hui, the stem cells provided by the Chinese bone marrow library are all peripheral blood stem cells collected by the machine. At present, only inter -relative transplantation will choose "bone marrow stem cells+peripheral blood stem cells" transplantation scheme. She explained that this was because the bone marrow was performed under the doctor's hemp. The puncture needle must be tied into the bone marrow cavity. The donor needs to bear a certain amount of pain. However, the bone marrow stem cells are rich in mesenamed stem cells, immune active cells, etc. After being transplanted into the patient's body, it can improve the micro -environment of hematopoiesis. it is good.

"As long as I can save my dad, I am not afraid of pain!" Weng Fanglei's strength made the transplant team unexpectedly and moved.

For an hour and a half of the bone marrow, Weng Fanglei didn't say a word.

He didn't even say a word of 51 stitches

The 54 -year -old father Weng was 1.76 meters tall and 82 kg. According to the standard of 20 ml/kg, 1000 ml of bone marrow was required. In order to prevent the bone marrow fluid, due to excessive blood loss, the shock is life -threatening, and Weng Fangle's autologous blood is needed in advance.

On August 2nd, Weng Fanglei first came to the hospital to draw blood. "Why are you running alone?" Doctor Cheng Ping saw him coming alone, and he couldn't help worrying. Weng Fanglei was busy explaining that his mother was at work and was inconvenient to take leave. He usually went to school by himself and was used to it. For 3 weeks, Cheng Ping stored 1100 ml of autologous blood in three times.

Kou Ding Bladder isopic hematopoietic stem cell transplantation is started. Weng Haizhou transferred into a sterile layer flow ward for pre -treatment chemotherapy. It destroyed its own immune system through large dose of chemotherapy drugs and immunosuppressants, and for the implantation of the stem cells of the son Essence The pre -treatment of chemotherapy is over, and Weng Haizhou's mental situation is good.

5 days in advance, the doctor gave Weng Fanglei a mobilization agent. This is a kind of stimulus factors to be played a few days before donating hematopoietic stem cells. The role is to help promote the large amount of growth of hematopoietic stem cells, release it to peripheral blood, and separate from the blood. Cheng Ping said that this kind of needle is uncomfortable with adults.

At 9:30 am on the morning of August 23, Weng Fanglei followed the doctor into the bone marrow transplantation warehouse. Lying on the collection bed, every time the bone is pierced, it can collect 20 ml of bone marrow. After drawing 800 milliliters, the doctor asked every time: "Are there any uncomfortable? Can you persist again? Do you want to rest?" "I'm okay, you continue." There were 51 stitches above the tail vertebrae, and the picked patch was filled with the entire collection platform. Weng Fanglei did not say a word from beginning to end. Weng Haizhou is an AB RH positive blood, and his son Weng Fanglei is a type A RH positive blood. Because the blood type of the father and son is inconsistent, the 1003 ml of "life seeds" filled with 6 blood bags slowly lost to his father Weng Haizhou. Back in the ward, Weng Fanglei quietly told Cheng Ping that when he pulled his bone marrow, he had been reciting the chemical element cycle table in his heart.

Dr. Cheng Ping was extracting bone marrow for Weng Fanglei.

At 9 am on the 24th, the doctor once again collected 250 ml of peripheral blood stem cell suspension from Weng Fanglei. At 2 pm, after the collection, the "seed seeds" were immediately lost to Weng Haizhou's body. "Is your son okay?" As soon as Cheng Ping moved to the planting position, Weng Haizhou quickly asked the child's situation. It was learned that his son had a little pain and no other discomfort. Weng Haizhou's heart had been put down.

Weng Haizhou should wait for about 2 weeks in the transplantation warehouse, waiting for the stem cell seeds full of stem cells to grow, thrive, and rebuild normal hematopoietic and immune functions.

At 3 pm, Weng Fanglei returned home with his mother, and he would return to school for a week. "Each donor is a hero who saves people. You save your father, and you are also a hero." Director Cheng Hui encouraged Weng Fangle to study at ease and wait for his father's good news.

Weng Haizhou was accepting his son's hematopoietic stem cells and seeing his son outside the warehouse. He also compared a "V".

All -in -one brothers and sisters are the first choice for bone marrow transplantation

Cheng Hui, director of the Department of Hematology of the First Hospital of Wuhan, introduced that the bone marrow pairing of the hematopoietic stem cell transplantation requires the bone marrow pairing of the suppliers and the recipient must be fully consistent, that is, the "all -in -one", otherwise it is easy to cause rejection. Among the brothers and sisters of the compatriots, the probability of a total of 25%is 25%, and among the people without blood relationships, the probability of a full -combination is only 100,000. Weng Fanglei and his father accepted the "Molding Symphony Plant", which is also called "semi -compatible" transplantation. As long as half of the white blood cell antigen between the supplier and the recipient is the same.

Dr. Cheng Ping, who is responsible for transplantation, told reporters that during pregnancy, the child is a foreign body relative to the mother, and the mother's body will produce antibodies against the child's genotypes. The more pregnancy, the more antibodies in the body. Therefore, the first choice of bone marrow transplantation is the combination of compatriots, followed by the unmarried sisters of the compatriots, and the semi -fellow father and cousin cousin again.

Cheng Ping revealed that, compared to the bone marrow bank donation in the bone marrow database, the chance of donating the marrow in love between loved ones is greater. He explained that the marrow detection was the principle of the main compatibility of the tissue. However, the number of semi -phase hematopoietic stem cell transplantation technology is difficult and risky, and the number of hospitals that can carry out this technology in China is very limited.

Cheng Ping said that Weng Haizhou's treatment cost was around 300,000 yuan, and there was still a gap of 150,000 yuan.

【Edit: Fei Yinmei】

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