How many people don't know that it is not cotton swab for doing nucleic acids?
Author:China News Weekly Time:2022.08.08
Under the epidemic, nucleic acid testing has become part of our daily life.
However, do you know what you reach into your mouth every day?
Because the nucleic acid swab looks like a cotton swab, many people are mistaken for cotton swabs.
So, what is the material exactly like a cotton swab? Why can't you use a cotton swab?
Not the "velvet swab" of a cotton swab winning cotton swab
The nucleic acid swab is not a cotton swab, but a velvet swab made of polyester or nylon fiber. It is a medical device and is non -toxic and harmless.
Nucleic acid swab is a member of the large army. The swab is a tool that achieves the function of collecting, removing, and applying through the adsorption material fixed on the one end of the fine stick. It has a variety of materials such as cotton, polyester, nylon, etc. It is widely used in medical, epidemic prevention, forensic medicine and other fields. Among them, the cotton swab is the longest and the most widely used, so there is a "cotton swab" interpretation in the English translation of the swab.
In the field of nucleic acid testing, the main purpose of the wound is to collect new crown viruses that may exist in the general public, and need to have the best "adsorption".
However, the cotton swab is limited in the "adsorption" function. Instead, it is better to "adsorb" the nylon material.
Nylon is a artificial fiber that we know in life. Most of them appear in the form of textiles. They are famous for poor water absorption in the field of clothing. The status of nylon fiber fabrics is significantly lower than that of skin -friendly, sweat absorption, and breathable cotton. Human disgust.
So, how does the nylon fiber that does not suck well, is it good at "adsorbing"? Relying on technology.
The cotton swabs made of nylon fiber are used with velvet technology.
Studies abroad have proved that the "adsorption" efficiency of the nylon velvet swab is 20%~ 60%higher than that of other places. In addition to the high efficiency of "adsorption", the nylon velvet swab also has the advantage of "collection" time.
Plugs usually need to complete the pathogen collection work in a short period of time: the velvet nylon swab can be absorbed and collects samples in only 3 seconds to 11 seconds; the sampling time of the cotton swab is up to 15 seconds to 120 seconds, which will greatly increase the significant increase, which will increase significantly, which will increase significantly, which will increase significantly, which will increase significantly, which will increase significantly, which will increase significantly, which will increase significantly. The people open their mouths and queue up.
But as a collection function, it requires a good ability.
Good at release and "fresh -keeping" velvet swab
In addition to high "adsorption" efficiency, the nylon velvet swab also has the advantages of "release power".
The shit is just a carrier. In addition to being good at capturing and adsorption when collecting, it must also release the collected pathogens in the testing stage, and the release results are stable, and the concentration of the reagent is not diluted.
The cotton swab is poor in "release" in the pathogen and is extremely vulnerable to the diluted concentration of the reagent.
The collection experiment of a domestic pathogen found that the release efficiency of the velvet nylon swab to the pathogen is almost similar to that of the non -dilution concentration. It is low, and the results are more affected by the dilution concentration.
The velvet nylon swab is closer to the control group value
When the pathogen is attached to the surface of the wound, there is a certain risk of mutation. Compared with the comparative test found that the velvet nylon swab is better than "inhibit" the pathogen mutation than the cotton swab to ensure the "freshness" of the pathogen.
The demeanor in the red frame is far lower than that of the cotton swab
Therefore, the demented nylon swab that is good at adsorption and release is like a workplace person who can flex and stretch, preserves quality and quantity, and is better at deep cultivation in the field of pathogens.
So, how does the velvet nylon swab "be free and release" and "quality and quantity" in the testing session?
The cheats of the velvet swab "freely and release"
The "collection" of the velvet nylon swab comes from its innate advantage in its structure.
Because the velvet nylon swab is composed of countless small nylon fiber fluff, it has significantly increased its surface area, and also increases the physical advantages of adhesion and release of diseases.
Velvet nylon swab under microscope
In addition to the "free collection" of the velvet nylon, the pathogen is also "gentle". Foreign studies have found that the velvet nylon swab can increase the vitality of 20%to 60%, and in the sample testing more than 90%of the velvet swabs, almost fully releases the adsorbed pathogen. In particular, it has obvious advantages in the release of cells, microorganisms, and viruses.
In contrast, the cotton swab contains a variety of fatty acids. When it comes to contact with the pathogen for a long time, there is a possibility of "poisoning" pathogens.
Originally, the ability to grasp the pathogenic bodies of the cotton swab was relatively inferior due to structural disadvantages. It also had the "superpowers" of some of the pathogens "to kill", which would lead to the sharp decrease in the number of diseased rings, which may produce adverse consequences of false negatives.
But we also have to see the advantages of cotton products. Although the cotton dower is not reliable on the virus detection, the ability of "killing" part of the pathogens is an excellent "superpowers" on clothing and masks, which also proves that the older generation is obsessed with pure cotton fabrics. Essence
As for the detection of the new crown virus, it is still necessary to leave a better rush nylon.
Reference materials:
[1] Bayajie, Jin Ming, Wang Lingsheng, etc. The nylon velvet swab and the cotton swab blood stain DNA typing effect comparison [J]. China Legal Medicine Journal, 2015 (3): 4. 4.
[2] Zhou Lan, Sun Xuan, Niu Zhanqin. Velvet nylon and cotton sampling swab to release the ability to release E. coli culture [J]. Chinese drugs and clinical, 2013, 13 (1): 3. 3.
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