[Zi Niu Toutiao] Nanda Beauty Alumni publishes heavy papers in top journals: I want to return to work and miss Nanjing duck blood fans

Otherwise, the right to investigate legal responsibility

"Nature" magazine has recently published a heavy paper that reveals the new target of Parkinson's disease treatment. This is the result of Zhang Ying, an alumni from Nanjing University from Nantong, Jiangsu. After fierce competition with scholars, she also won the 2022 Harvard Outstanding Chinese Life Science Research Award. On the road of scientific research, Zhang Ying experienced countless sufferings. He had thought about giving up, but finally persisted, and achieved ideal results, and also received his dad's reward. Recently, the Yangtze Evening News Zi Niu reporter contacted Zhang Ying. She told the reporter with a smile that she grew up watching the Yangtze Evening News and talked about the award. Work hard, always on the road ... "

Beauty Alumni Published Top Papers

Provide new ideas for the treatment of Parkinson's disease

On June 18, the Harvard Outstanding Chinese Life Science Research Award will hold awards ceremony, and Zhang Ying, an alumni of Nanjing University, won the prize.

Just a few days ago, she published a paper in the Nature Magazine Magazine. Through the study of the Hilli Ring Road, she first revealed the mechanism of motion and non -exercise symptoms in Parkinson's disease and non -exercise symptoms.

Zhang Ying told Zi Niu Journalist that patients with Parkinson's disease will mainly have exercise abnormalities, and the most obvious is hand trembling. For the abnormalities in Parkinson's disease movement, many scientists have been conducting research, and at the same time, the existing treatment methods can also play a good alleviating effect on the abnormal exercise function.

However, Parkinson's patients will encounter many non -exercise abnormalities, including depression, but there are no very effective treatment so far. "Our job is to find a brain area of ​​the hill brain, and find that regulation of the Parkinson movement and non -sports functions can be improved at the same time." This study reveals the corresponding molecular target of Parkinson's disease, which is Parkinson's disease. The treatment provides new ideas and new directions.

"Nature" and "Science" (Science "and" Cell "are also known as the top three journals. They are the most authoritative, most influential, and most comprehensive academic journals in the global scientific community. When many researchers mentioned these three magazines, they simply took their English first letters, referred to as CNS for short.

Zhang Ying was from Nantong, Jiangsu. When I contacted the reporter, she laughed and watched the Yangtze Evening News growing up.

Her family comes from rural Nantong. Her parents work very seriously. She said that her father was very motivated, and she was very hard -working. After step -by -step efforts, "bring our family from the countryside to the town, and then come from the small town to In the city. "

This way is not easy. Zhang Ying is very influenced by his father. "Because he has been teaching me to be optimistic, we do scientific research. Many experiments have failed. Very big. My mother is particularly inspired. I encounter any difficulties, and she can encourage me well. "Now Zhang Ying's father earns millions of income, which also solves her worries for her scientific research.

Zhang Ying, who is concentrated on scientific research

Undergraduate studies at the School of Life Sciences

"Still miss the food around Nanda"

In elementary school and junior high school, Zhang Ying's academic performance was not particularly excellent. She went to a relatively ordinary town high school. However, after entering high school, she suddenly opened up, and her academic performance was getting better and better.

In the 2008 college entrance examination, I chose Nanda Life Sciences. She felt that it was a coincidence. "I especially liked English and wanted to choose an English major, but the enrollment teacher asked me which subject was better. Two colleges, one is the English department, and the other is the School of Life Sciences. It is said that these two colleges are very good, but the research rate of the School of Life Sciences is a bit higher. My parents think that students can be a scientist in the future. It is a very proud and glorious thing, I chose this major and entered the School of Life Sciences of NTU. "She has experienced the three campuses of Drum Tower, Pukou and Xianting. In Xianlin, the senior year went to the Gulou Campus. When she was in Pukou, she still remembered that she had to take a car through the Yangtze River Bridge when she was shopping. She never forgets the "Uncle Dumplings" of the Drumstick Campus, as well as food such as trotters and duck blood fans of small powder bridges.

After graduating from the University in 2012, Zhang Ying entered Zhejiang University for research in the direction of neuroscience, and obtained a doctorate degree in 2017. After graduating from the PhD, she went to the laboratory of Feng Guoping, a professor of the McGen Institute of Brain Science, McGonin Institute of McGenics, USA in July 2017 for a postdoctoral study.

The outside of the brain is the cortex, the hill brain is in the middle of the brain, and the area wrapped in the middle of the cortex is the mound brain. Because the location is relatively deeper and the current research technology is not very mature. Compared with other brain areas in the brain, the current research on the brain of the scientific community is not deeply deepened. Traditionally, the hill brain only plays a "bond" role, collects sensory information from various organs, and passes it to the cerebral cortex for processing. With the deepening of research, scientists are increasingly aware that the hill brain may not only be a "bond", but it can also participate in the encoding process of various high -level behaviors.

Considering that there are still many unknown areas of the mound, Zhang Ying chose it as the main goal of post -doctoral research.

Beauty Xueba learns that you can't care about your image

5 years like a day in high pressure work

"The competition in the scientific research field is fierce"

Some people think that scientific research work is superior to the real society. It seems to be an ivory tower. In fact, every scientific researcher is under tremendous pressure to work. Zhang Ying is the same.

During her post -doctoral research, she had been working for almost 5 years, and she had been working. She only returned to China once and returned to the laboratory after a week. "The experiment is a very continuous big project. If the time is particularly long, there is no way to publish an article as soon as possible. "

她每天在实验室里待上八九个小时，每周工作6天，相对某些研究者来说可能不算太长，“但是我回到家之后，晚上的时间仍旧是忙工作，包括星期日， There is very little time not to think about your own subject. It is always in the working state, because you are not working for others, but work for yourself. Whether your project can make good progress is your own business. If it is not good, you will not get good research results, so in vain in recent years. "

Scientific research also faces fierce competition. "There are many research groups in each research direction, and many people around the world are doing this project at the same time, but the article is always the first person. The most powerful. If someone comes the results first, the people in the back are basically equal to doing it in vain, so the scientific research competition is very fierce. "

Many people are doing Zhang Ying's research topics. When she is preparing to submit, it is found that a research group has just published a particularly similar article to her research direction, which surprised her a cold sweat. "Let's see After that article, I withdrew the manuscript that was thrown back, and took half a year to make up the experiment for half a year, and changed the framework of the entire article, and finally contributed to "Nature". "

In the past few years, in addition to publishing a paper in the first author of Nature, she has also published a paper in the "Nature". (Nature Neuroscience) and other journals have published results. However, this process is not smooth, and has experienced many rejection and modification experiments.

She had doubts about her work more than once, and once thought about giving up the path of scientific research. "Sometimes I think that it is not worth doing this thing to the bottom. To do one thing, it is necessary to consider how good it can be done. If you do your best, you can get it well. Can you accept such cost -effective? The cost -effectiveness of scientific research is still quite low. Among the people we do scientific research, we are full of some particularly smart and competitive groups of people. Big. But if you go to other fields and bring this scientific research to other fields, relatively speaking, your competitiveness will be much larger than others. In addition, cakes in other fields may be relatively large, so There may be a lot of results in the end. "

In the process of doing scientific research, she learned to get along with herself, adjust her goals in a timely manner, and not compare with others. When she exchanged scientific research experience with netizens on "Little Red Book", "I still remember when the article was rejected by the" Science "magazine, it seemed like my sky collapsed, and a person cried in the room for a long time. I think I have no future. I think about it now, very stupid and ridiculous, life is long, the world is very big, why bother in one place! "She shared the scientific research process on Xiaohongshu

Posted a top article to get Dad's reward

"I have been working hard, always on the road"

Some netizens said that they can publish papers in the three top scientific magazines in CNS, and they are definitely "great gods". Peng Li, an associate professor of Guizhou University of Traditional Chinese Medicine, published a research paper in the "Nature" outer issue as the first author on April 27, and the school rewarded Peng Li's individual 1 million yuan. In the postdoctoral recruitment announcement released by the University of Macau Macau, the Institute of Science and Technology of Zhuhai Macau also stated that if a postdoctoral post is published in the top international academic journal "Nature" or "Science", each rewarded 1 million yuan. There are many institutions that launch similar rewards mechanisms.

The American scientific community also recognizes the value of publishing papers in these three magazines, but there are not many cash rewards. Zhang Ying's father directly rewarded 500,000 yuan in order to encourage her daughter. "I have a good academic performance since I was young, and I will reward at home. When I published an article in China, the school would have various rewards. During the post -doctoral period in the United States, there were basically no scholarships. Lost, began to complain to the family that the post -doctoral after -do is too poor, and there is no additional income. Then my dad asked me to engage in scientific research, "I will give you a reward."

Zhang Ying in life

Zhang Ying's father said that as soon as the thesis was launched on the official website of "Nature", the 500,000 yuan bonus at home arrived. "My mother said that she had a sense of ritual, so the bonus was basically synchronized with the article."

Post -doctoral research is about to end. Zhang Ying wants to return to China and is actively looking for work.

Recently, she also got a good news. After fierce competition with the "great gods" who had published research with various roads in CNS, she won the first award during the post -doctoral period: Harvard Outstanding Chinese Life Science Research Award. After getting the news, the mentor was very excited to send an email to the entire laboratory. Zhang Ying said, "This award belongs to me and also belongs to my partner. I am very happy and grateful! This award is a reward for the previous work and the incentives of future work. We hope to bring you more in 2023 to bring you more A lot of surprises! I've been working hard, always on the road ... "

Zi Niu Journalist ｜ Song Shifeng

Edit ｜ Zhang Bingjing

Editing ｜ Wan Huijuan

Editor ｜ Chen Dichen

Material source: interviewee provided

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