Tsinghua's technology, helping patients with paraplegia regain walking!

Artificial spinal technology

For more than 3.7 million patients with damage to my country, the significance of this result is huge.

In the operation, an artificial spinal cord system is implanted to intelligently optimize regulation and targeted rehabilitation training. Recently, a paraplegia patient in a car accident successfully achieved step forward step by step.

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The results were completed by Tsinghua University's neurological regulation of the National Engineering Research Center and Changping Laboratory and Beijing Tsinghua Changgeng Hospital. Under the joint tactics of the team, the artificial spinal cord system played magical effects in the patient's body and achieved synergy with patients. From the unable to move to the lower limbs to the gradual restoration of the autonomous movement function, to the realization of independent standing and holding a helper to walk independently, the scenes in science fiction movies have entered the reality.

Spinal nerve regulation helps paraplegia patients regain walking

Spinal cord injury is called an irreversible "worldwide problem". The disease part or all blocks the connection between the brain and the peripheral nervous system, which seriously affects the encoding and transmission of downlink control signals and uplink sensory signals, causing motion and sensory function loss or even completely lost in the body area below the body area. Almost all patients with spinal cord injuries are accompanied by the irreversible limbs or both lower limbs paraplegia, causing failure to live normally and engage in physical labor. At the same time, inpatient therapy and subsequent rehabilitation costs are as high as millions of yuan, bringing a heavy burden on patients and society.

Li Luming, the team leader and director of the National Engineering Research Center of Neuroma, introduced that the artificial spinal cord project team based on the research experience of brain pacemakers, after years of technical preparation, with the support of the National Engineering Research Center and Changping National Laboratory, in 2021, 2021 The clinical trials of patients with spinal cord injury were officially carried out, recruiting the first paraplegia patients in lower limbs who were injured in complete spinal cord injury. By planting high-density stimulating electrode arrays in the patient's spinal hard membrane, and the nerves related to the spinal cord region and the lower limbs and torso movements based on the rhythmic sequence stimulation of time-time-coded, re-construct the exercise instructions to help patients restore it to it. Part of the control of the lower limb muscles rebuilt the patient's walking gait. After a period of rehabilitation training, patients gradually resumed sports functions such as standing and walking.

In recent years, spinal nerve regulation The treatment of spinal cord injury has become a hot spot in the academic world. It is a benchmark for the combination of engineering science, neuroscience and clinical medicine to solve clinical challenges.

The patient completed surgical implantation in neurosurgery in Tsinghua Chang Gung Hospital, and then conducted rehabilitation training in the Department of Rehabilitation Medicine. "Just like the cable cannot continue to communicate after the cable is broken, the nerve signals of patients with spinal cord injury cannot be passed normally between the brain and peripheral nerves. After implantation of an artificial spinal cord system, transmit the motion signal sent by the patient to the damage site through electrical stimulation, and use the nerves to use the nerves The inherent loop function acts on the patient itself and supports him to complete the exercise instructions to achieve the reconstruction of exercise. "Wang Guihuai, director of neurosurgery of Tsinghua Chang Gung Hospital, said.

"After the team confirmed that the patient entered the rehabilitation platform period, the artificial spinal cord system was implanted, and the subsequent spinal cord nerve regulation and rehabilitation helped the patient re -establish the adaptive control of the muscles below the damage. The patient first restored the simple autonomous movement function Later, with the assistance of weight loss equipment, it realized independent standing and walking. Now it can get rid of the independent walking and holding the framework of the weight loss equipment. "Pan Yu, director of the Rehabilitation Medical Division of Tsinghua Chang Gung Hospital, introduced.

Patient's autonomous walking gait analysis

The team member and Associate Professor Yan Yanan, a team of Tsinghua University, introduced that the artificial spinal cord system allowed patients with spinal cord injury to lose their physical exercise ability to restore independent control of muscles below the damage. The intelligent regulatory technology developed by the team can optimize the regulatory strategy according to the patient's motion performance, realize the real -time adjustment of parameters and freely switching of multiple motion modes, adapt to patient needs, and help patients perform simple daily activities. After optimizing regulation and rehabilitation training, the recovery effect of patients has been greatly improved.

Serving the China Strategy and improving the level of national health, an innovative therapy for artificial spinal cord technology is opening a new path for the rehabilitation of patients with spinal cord injury. “这一工作在全球都处于探索阶段，是一项挑战巨大、交叉性很强的研究，多学科研究人员需要与患者通力配合，克服各种困难，推动临床应用。让人欣慰的是，在In this process, I witnessed the step -by -step improvement of the patient's movement function, and also exercised the team, especially the doctoral students' ability to solve the problem. Work hard. "Li Luming said.

The first artificial spinal cord subject was in Tsinghua Garden

During the 111st anniversary of Tsinghua University, the artificial spinal cord subject came to Tsinghua Garden to show his rehabilitation treatment effect through independent walking. The results of the team for many years can help those who need more need to help more people. Li Luming said, "This is a very lucky thing for us."

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