Headquartered in Pingdingshan, the first domestic new crown oral medicine Azf fixed film is put into production today

Top News · Henan Business Daily reporter Sun Chao

On the morning of August 2nd, Azf's setting in the new coronal virus pneumonia indication was held in Henan True Biotechnology Co., Ltd., Henan True Biotechnology Co., Ltd., Henan Trinity Integrated Demonstration Zone, Pingling Mountain, Henan Province.

Real creature is a biotechnology company that drives R & D as a driver. It is dedicated to the development, manufacturing and commercialization of innovative drugs for the treatment of viral, tumors and cerebrovascular diseases. The company pursues innovation, constantly finds updated and better treatment plans to meet the unsatisfactory clinical needs, and gradually establish the company's advantages in the development of antiviral and antitumor drugs. Essence

As the first anti -new crown oral medicine in my country, what is the performance? Is it safe?

The main efficacy indicators of Azf's fixed tablet for the treatment of new coronary pneumonia indications have reached expectations. The Azf fixed film, which has been approved for more than two years of clinical trials, is expected to become my country's first oral anti -new crown drug with completely independent intellectual property rights!

On July 15th, Henan Real Biotechnology Co., Ltd. (hereinafter referred to as "real creature") announced that it has officially submitted a listing application to the National Drug Administration for a listing application for the treatment of new coronary virus indications for the treatment of new coronary viruses.

Since April 2020, Azf has been approved at home and abroad to conduct phase III clinical trials at home and abroad. The clinical trial results show:

Significant improvement of clinical symptoms. Azf's fixed tablet can significantly shorten the moderate new type of coronary virus infection with pneumonia patients, the proportion of patients with improvement of clinical symptoms, and achieve clinical excellent results. On the first 7th day of the administration, the proportion of the subjects of the clinical symptoms improved 40.43%, and the placebo group was 10.87%(P value <0.001). There are very significant statistical differences with the placebo group (P value <0.001). (PPS set)

Inhibit the role of new coronal virus. Azf's fixed film has the activity of inhibiting the new coronary virus, and the virus clearance time is about 5 days.

In terms of safety. The overall tolerance of Azf's fixed film is good, and the incidence of adverse events has no statistical differences with the placebo group, and the risk of the subject has not increased.

It is understood that Azf's fixed film is the world's first dual -target anti -AIDS innovation medicine, and has applied for patents in many countries such as China, the United States and other countries. As a antivirus small molecule oral medication, Azf's fixed tablet has a broad -spectrum to inhibit RNA virus replication, while the new coronal virus belongs to RNA as the virus of genetic material, so the medicine has inhibitory effects on the new crown virus.

Dr. Du Jinfa, the chief scientist of the real biology, said: "We are very happy to usher in this important moment. I look forward to the approval of Azf's fixed film as soon as possible to provide a force for the prevention and control of domestic and global epidemic conditions."

Azf Fixed Pharmaceutical inventor, former president of Henan Normal University, professor Chang Junbiao, deputy secretary and vice president of Zhengzhou University, said: Allaxyococcus, which can specificly act on the new coronary virus RDRP, thereby inhibiting virus replication, and its drug is targeted. "

Jiang Jiandong, an academician of the Chinese Academy of Engineering and the dean of the Beijing Academy of Pharmaceutical Research, Chinese Academy of Medical Sciences, said: "Azf's fixed tablet has obvious anti -new coronal virus effects, which is effective for patients with clinical enlarged diseases. The new crown of molecular mechanism is its unique biological characteristics. "

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