The results of a research of our school were published in Cell ("Cell")

On July 14, the top international journal Cell ("Cell") published an online publication of our school's plant immune team after 18 years of research results -discovered the "true murderer" of the infection of rust -in infection in wheat - Through knockout sensor genes, the wheat is not easy to be infected by rust bacteria, which has opened up new ideas and new ways to breeding disease -resistant wheat breeding.

Wheat is one of the most widely planted grain crops in the world. It provides staple foods for more than 2.5 billion people worldwide and is the most important grain crop. However, pests and pests often cause major losses of wheat output, which seriously threatens food safety. Wheat rust is a fungal disease with ingenuity. It has the characteristics of vulnerable and popularity. It is a major biological disaster on the number one in wheat. my country has always been the heaviest area. Since the founding of the People's Republic of China, eight major popularity has occurred. After the prevention and treatment, it still lost a total of 13.8 billion kilograms of wheat output. It is called the "cancer" of wheat. Crop disease.

Wheat rust disease spreads due to rust bacteria. Rust bacteria is a kind of fungus with living nutrition parasites that depend on living wheat to survive. The plant immune team focuses on the nutrition parasitic characteristics of wheat rusty bacteria, and tapped the world's first wheat sensor gene TAPSIPK1, which was used by the toxic protein of the germs -coded cytoprocin kinase. The basic immunity of the sensor of the diseased genes, the toxic protein PSSPG1 that can be secreted by the rusty bacteria, the release of the cell nucleus from the cellular membrane, the transcription factor TACBF1 in the nuclear operation of the cell, inhibit the transcription of the resistance -related genes, and enhance the transcription level of TAPSIPK1. Apricate Tapsipk1 -mediated sensing effects and promote wheat sensation. The results system revealed the sensorization mechanism of the phosphorylation and transcription regulatory level of PSSSPG1-TAPSIPK1-TACBF1D. And using gene editing technology to precisely knockout sensor genes, destroy the identification and interaction of toxic protein and sensory genes, and realize the broad -spectrum resistance of wheat to strip rust. In the field test, the wheat editorial department shows the characteristics of high anti -strip rust on the premise of maintaining the main characteristics of the crops and has good application potential.

Work mode of a sensory genetic gene

The significance of this achievement is that the original major achievements in the identification and utilization of wheat sensing genes are the leap breakthroughs in the realization and control of the species and the original independent innovation capabilities of the seed industry. First, the discovery of wheat sensing genes is a major breakthrough in the field of plants and pathogenic fungus, marking a big step in my country in this field and at the world's leading level. The second is to break the traditional ideas of wheat mainly using the genetic breeding of disease resistance, enrich the type of genes available to disease -resistant breeding, open up a new way for wheat biochemical breeding, and provide scientific and technological support for my country's modern biological breeding and disease green prevention and control.

Wang Ning, a postdoctoral of our school, associate researcher of Tang Chunlei and Fan Xin, a doctoral student, is the first author of the paper. Professor Wang Xiaojie and Academician Kang Zhen Sheng are communications authors. Our school is the first author unit, and researcher Zhou Jianmin of the Institute of Genetics and Development Biology of the Chinese Academy of Sciences participated in the research work. The research has been supported by the national key R & D plan projects, the National Natural Science Foundation of China, the 111 project of the State Administration of Foreign Affairs, the national wheat industry technology system, and the Shaanxi Provincial Science and Technology Innovation Team.

Edit: Zhang Qing

Trial: Xu Hai

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