Chinese medicine can improve the age of methylation
Author:Yueyang Daily client Time:2022.07.29
The process of human aging is a process of physiological, pathological, and psychological interweaving. Among them, interpretering genetic changes and metabolic dysfunction are two signs of aging. DNA methylation is a widely researched apparently genetic modification method. Some people say that it is like a "magic hat". It regulates the function of genome without changing the DNA molecule first structure. It plays an important role.
Recently, research teams from the Institute of Animal Research of the Academy of Sciences, the University of Science and Technology of my country, and Macau University of Science and Technology published an article in the "Signal Transdu and Targeted therapy" magazine, revealing the obvious genetic metabolism axis that promoted aging. Researchers have found that by detecting the level and expression level of Elovl2's DNA methylation, and applying artificial intelligence methods to predict the protein structure of ELOVL2 and its interaction with the substrate, improve the stem cell failure and cognitive ability caused by the reduced expression of ELOVL2 expression. Decreasing, retinal degeneration, and glucose intolerance of cells and physiological levels. This shows that DNA methylation is used to regulate gene expression by integrating environmental signals to play a key role in aging.
The smaller the degree of DNA methylation, the younger the body is
Aging is a process of gradually developing in accordance with the life cycle, which causes causes to involve multiple factors. As the age increases, the level of armor -based opticalization of the human body will change, which will affect the expression of each gene and show aging performance.
Studies have found that the physiological age of different tissues and cell types of human beings is highly related to the degree of methylation of the genome DNA. The smaller the degree of DNA methylation, the smaller the calculated physiological age, and the smaller the body aging. Diseases, aging, bad living habits, etc. can all leave a mark on DNA through epigenetic methods such as DNA methylation.
In 2021, research papers published by researchers at the University of California, San Diego in the scientific research journal "AGING" showed that clinical random control experiments on adult men aged 50-72 years old. In 8 weeks, they Strictly accept diet, sleep, exercise and relaxation guidance, and supplement plant nutrients. The experimental results show that the average physiological age of participants is 3.23 years old. This discovery undoubtedly brings new hope for the long anti -aging exploration of human beings.
The aging itself is not terrible. It is terrible that a series of diseases burst out of aging, such as tumors, heart disease, vascular atherosclerosis, osteoporosis, and degenerative lesions of the central nervous system. With the "International Disease Code (2018)", it is clearly stated that aging is regarded as a treatment that can be treated, and more and more enterprises and scientific research institutes have participated in it. Anti -aging turns began to pay attention to some diseases related to aging.
Chinese scientists have also made major research progress in the anti -aging of Chinese medicine. The eight -sonic kidney can improve the age of DNA methylation, and the "Athletics theory Guidance of the Eight -Son Nujian Anti -Aging Research Project" carried out by the National Key Laboratory of Chinese Medicine National Key Laboratory of List disease and innovation. The latest discovery can improve the age of DNA methylation.
Traditional Chinese medicine has the characteristics of overall regulation. Whether it is small molecular drugs or compound drugs, it has a very clear and wide range of effects, which can achieve multi -purpose and multi -target therapy. It can delay aging by improving the level of methylation. For a series of diseases that occur during aging, such as atherosclerosis, osteoporosis, and degenerative lesions of the nervous system, they also have multi -target and multi -target intervention Regulate.
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