As a doctor, she felt different for the first time

On Sunday, Dr. Li, who was on duty, suddenly felt cold. Solid medical knowledge told her: Maybe it's a fever!

Climb up and take out the forehead gun from the drawer. "Papa" twice, 37.2 ℃.

Seeing this value, she almost stunned: I haven't had a fever for more than ten years! Even in the state of raging epidemic, she never worried that she would have a fever, let alone other reasons that the fever was mistaken for the infection of the new crown virus.

This is how to do? Her brain rotates at high speed ...

If it was just a fever, she would not care. However, she faintly felt that the muscles of the two legs had been sinking, and her waist and back muscles became more and more sore. This shows that the disease is developing and it must be terminate!

Because there are no obvious symptoms such as cough, sneezing, or sore throat, the cause cannot be determined for a while, and the urgency is to control the symptoms.

So she called the anorectal and asked them to help them drive a pain relief.

This kind of bolt is a non -sterite drug, which has both the effects of heat and analgesic. It is a drug that is commonly used for postoperative analgesics. At the end of the surgery, just stuff it into the anus. It is said that the effect is not bad.

After she was on the bolt, she lay again on the bed and waited for the drug to take effect. Pray in my heart: Don't come to emergency surgery at this time! At the same time, she carefully felt the process and effect of the drug results.

As an anesthesiologist, pharmacological knowledge is very solid. She is very clear about the theory of anal medication. This time, she must practice well.

If you take the medicine orally, you may have sweat and other performances in a few minutes, but this time the anus medication is not so fast. At this time, she analyzed that the anal medication may be slightly slower than orally.

At this time, she not only faintly worried about the side effects of the gastrointestinal reactions mentioned in the instructions. Her past experience told her: she was an out -of -the -box halo. Whether it is a car or a plane, it is a vomiting.

Half an hour later, the expected side effects were not so obvious, but the intestinal peristalsis was accelerated.

The gradually relieved muscle soreness and the forehead that had become cold, she knew that the drug had worked.

According to the dose of the drug, she obviously feels that the effect of the anus medication is better than orally. She immediately thought that this was because of the first elimination effect.

The first elimination: Drugs that absorb the entry venous system from the gastrointestinal tract must pass the liver before reaching the blood circulation of the whole body. If the liver has a strong metabolic ability or a large amount of bile excretion, the effective amount of effective drugs entering the whole body blood circulation obviously obviously obviously obviously A decrease, this role is called the first customs clearance.

However, the anal medication, the drug directly absorbed into a large cycle from the vein, the lower vein, and the anus vein in the rectal vein, thereby avoiding the "commission" of the liver in the middle. In addition, the tongue can also avoid the first elimination.

Here, explain the problem that a anesthesiologist is often asked: well, can you drink some hemp medicine?

This answer is uncertain.

For example, some medicines are afraid of sour or alkali. If you are afraid of sour, you will lose all the martial arts at the moment when you see the stomach acid; if you are afraid of alkali, you won't be long. Out of the pyloric door of the stomach, it immediately entered the sour alkaline environment. How long can I "live" can only look at the process of medicine.

Only those anesthesia that is not affected by acid -base can play a role. However, due to the effect of the first customs clearance, only a few percent of its skills are left. Therefore, orally can be added.

What other questions do you have? Welcome to leave a message to communicate ~

[Reminder] Pay attention, there are a large number of professional science sciences here to reveal those things about surgical anesthesia ~

- END -