How to deal with triglycerides?Expert tips: Check the liver function and sugar metabolism.

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At present, for patients with elevated triglyceride, how to deal with evidence is still lacking. Recently, an article published in "Circulation" states that triglyceride increased indicates that there are excess energy in the body and have been converted into visceral fat. Ecositive fat accumulation has appeared in skeletal muscle, liver, pancreas, and heart.

In this case, pay attention to check liver function and blood glucose metabolism, such as gifda aminotransferase (ALT) and γ-glutamyl rigidase (GGT), glycated hemoglobin (HBA1C), and / or empty blood glucose to determine Whether there is an heterogeneous fat. (Circulation. Online version of July 11)

The article pointed out that patients with elevated triglyceride should pay attention to the following four issues:

First, eliminate secondary causes, such as kidney disease syndrome, liver disease, alcoholism, high carbohydrate compounds/high -calorie diet, obesity and thyroid dysfunction.

It is worth noting that there are diabetic patients with severe insulin resistance, and poor blood glucose control will also increase triglyceride. But with the improvement of blood glucose control, the level of triglyceride will be reduced.

Second, when triglyceride is found, Alt and GGT, and HBA1C and / or air -stomach blood glucose should also be checked. For patients with overweight/obesity, triglycerides are often coexisting with degeneration of liver fat, which can be measured by direct (ultrasound or magnetic resonance imaging), or can be inferred by Alt or GGT.

If there is heterosexual fat, the level of Alt and GGT may increase slightly. For those who do not drink, the level of ALT and GGT may have non -alcoholic fatty liver.

The "ectopic fat" theory can explain why the level of triglyceride levels is increased. If patients can reduce weight, blood indicators often improve at the same time.

However, it should be noted that not all patients with different levels of fat have all the above characteristics.

Third, there are often evidence of sugar metabolism abnormalities, such as higher HBA1C or sensitive people with diabetes (with a family history of type 2 diabetes).

Studies have shown that compared with ALT <20 U/L, people with ALT are 30 ~ 35 U/L.

4. Improve lifestyle, give priority to improving diet and increased physical activity, can reduce heterosexual fat, while reducing triglyceride, ALT and (or) GGT, and HBA1C levels.

The author believes that more and more evidence from genetic analysis and Monteer's randomized research shows that the elevation of triglyceride has a causal relationship with the risk of atherosclerosis cardiovascular disease, and reducing weight and reducing related glycerol triglycerum levels It will also reduce the risk of atherosclerotic sclerosis cardiovascular disease.

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