Vaccine R & D Course: Activated vaccine and MRNA vaccine have their own characteristics that cannot be simply distinguished by advanced or backward

Cover news reporter Shao Meng

On July 23, the State Council's joint prevention and control mechanism held a press conference to introduce the relevant situation of the safety effectiveness of the vaccine vaccine of the new crown virus.

On July 23, the press conference of the joint prevention and control mechanism of the State Council. Cover reporter Shao Meng Photography

At the meeting, a reporter asked questions that among the new crown virus vaccines currently vaccinated in China, the vast majority of the activated vaccine and reorganized protein vaccine accounted for the majority of the MRNA vaccine in many countries abroad. Some opinion believes that the technologies of extinguishing vaccine have lagged behind, and MRNA technology is advanced technology. Is this the case? Why do other countries have no development of analogy vaccine?

Zheng Zhongwei, director of the Science and Technology Development Center of the National Health and Health Commission and the leader of the research and development of the research and development of the scientific research research group. Picture source: China Net

Zheng Zhongwei, director of the Science and Technology Development Center of the National Health and Health Commission and the leader of the research and development of the scientific research and research group vaccine, said that the activation vaccine is not a backward technology, but a mature classic technology. At present, spinal ashgone vaccines, hepatitis A vaccine, influenza vaccine, rabies vaccine, hand, foot and mouth vaccine, which are widely used worldwide, are all vaccines. This time, the research and development and production of the new crown virus vaccine has many technological innovation and process improvement.

Zheng Zhongwei introduced that MRNA vaccine technology rose in the 1990s. It was first used to develop tumor treatment vaccines. No products were approved to be listed before the new crown epidemic. The MRNA vaccine of the new coronal virus is the first time in history. Therefore, the MRNA vaccine technology can be called new technologies. The activation vaccine and MRNA vaccine have their own characteristics and must not be simply distinguished by advanced or backward.

Why do many developed countries have not developed an exciting vaccine for the first time? Zheng Zhongwei said that this is because the active vaccine involves a large number of live virus operations. It is necessary to build a high -grade biological safety production workshop in large -scale cultivation and purifying new crown viruses in a short period of time. It is difficult to determine whether high investment can get expected benefits at the beginning of the epidemic. In China, my country has taken the lead in formulating the relevant specifications on the construction of the new crown virus inactivating vaccine production workshop, and simultaneously carried out the development and production workshop construction of the new coronary virus vaccine at the fastest speed to ensure the large -scale production of the new crown virus activity vaccine production. need.

Zheng Zhongwei pointed out that foreign abroad has also been developing the research and development of new crown virus vaccines. For example, a new crown vaccine produced in India was also included in an emergency use list by the World Health Organization at the end of last year. use. Activated vaccines developed by Turkey, Kazakhstan, Russia and other countries are also being put into use. These situations fully show that activating vaccine technology is still a global recognized mature classic technology.

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