Middle disease control: BA.4 and BA.5 have enhanced communication capabilities ... to meet 3 conditions without all nucleic acids →

On the afternoon of the 21st, the joint prevention and control mechanism of the State Council held a press conference. The responsible comrades of the relevant departments of the National Health and Health Commission and experts from the China Centers for Disease Control and Prevention attended the meeting to introduce the relevant situation of science and accurate epidemic prevention and control, and answered reporters.

Recently reporting local gathered epidemic in many places in the country

The situation of preventing and control is severe and complicated

The National Health Commission spokesman Mi Feng said at the press conference of the State Council ’s joint defense and control mechanism today that at present, the global epidemic is still at a high level, and the newly -added diagnosis cases have exceeded 1 million times. Branch has become the major popular plants in the world, and the pressure on foreign defense input is increasing.

Recently, the local clustering epidemic has been reported in many places in the country. There are multiple transmission chains, and the situation of the epidemic prevention and control is severe and complicated. The comprehensive group of the State Council ’s joint defense and control mechanism has sent a working group to relevant provinces to guide the localities to control the epidemic at the shortest time and minimum cost.

Mi Feng said that we must adhere to the "external prevention input and internal defense rebound", adhere to the "dynamic clearing zero", strictly implement the ninth edition prevention and control plan and the "nine inaccurate" requirements, and do not relax. Prevention, early discovery, and fast disposal, comprehensively improve the efficiency of the entire chain, strive for science and precision, and strive to facilitate the masses.

Ninth Edition Prevention and Control Plan

It is the optimization of prevention and control measures, it is not relaxed

He Qinghua, a first -level inspector of the National Health and Health Commission's Disease Control Bureau, introduced that the ninth edition of the prevention and control plan is based on the characteristics of shortening after the virus variation, which corresponds to the time and control of the isolation and control of risk personnel such as immigration and close contact. Under the premise of ensuring the prevention and control of the epidemic, the use of centralized isolation resources has been optimized, and the impact of the production and life of the masses is reduced.

At the same time, the ninth edition of the prevention and control scheme encrypted the frequency of nucleic acid testing of risk personnel accordingly, which is conducive to the discovery of infection as soon as possible, and start the disposal early. The key to the ninth edition of the prevention and control plan is: one is to control the focus of the control, the other is to implement the measures that should be implemented, and the third is to resolutely cancel the cancellation.

Therefore, we must always tighten the string of the epidemic prevention and control, adhere to the overall strategy of "external prevention input, internal prevention and rebound" and the "dynamic clear zero" general policy. Coordinate the prevention and control of the epidemic and the development of economic and social development, protect the lives of the people's lives and health to the greatest extent, and minimize the impact of epidemic situation on economic and social development.

Omikon BA.4 and BA.5

Indeed, it shows the phenomenon of enhancement of communication capabilities

Dong Xiaoping, chief expert of the China Centers for Disease Control and Prevention, introduced that Omikon BA.4 and BA.5 have spread ability. If compared with other evolutionary branches of Omikon, it does show the phenomenon of increasing communication capabilities.

BA.4, BA.5 sub -branch caused

Both infection rate and mortality rate will increase

Dong Xiaoping introduced that the pathogenic force of BA.4 and BA.5 Asia branches is generally similar to other Omikon mutant strains, but the rapid spread among the elderly people has appeared in severe cases. Both the ICU usage rate has increased. Research on epidemiological mathematics models show that the infection rate and mortality rate caused by branches of BA.4 and BA.5 Asia will increase.

The mutation of the new coronal virus is long -term existence

Dong Xiaoping introduced that most scholars at home and abroad believe that the mutation of the new crown virus has long -term existence, and the mutant strain of Omikon is unlikely to be the last mutant strain. The impact on the propagation capacity, pathogenic ability, and immune escape ability produced by mutant strains will be the key content of our long -term attention.

After the epidemic

To meet these conditions, there is no need to perform full nucleic acids

At the press conference, Wang Liping, a researcher at the China Centers for Disease Control and Prevention, introduced that after the epidemic, if an epidemic survey, comprehensive risk research and judgment, meet the following conditions: clear sources of infection, clear transmission chain, and community transmission without occurring, there is no need to be right. A whole nucleic acid testing of the epidemic was carried out. Focus on risk -up risk -intersecting risk personnel to conduct nucleic acid testing.

11 mutant strains have been reported in this round of epidemic

What is the difference?

As of 24:00 on July 19th, according to incomplete statistics, 11 new types of Omikon -type mutant strains have been reported in 13 places in the territory.

Among them, there are 6 places for the evolutionary branch of Omikon BA.5, and 6 places for BA.2 evolutionary branch. Tianjin not only has the above two strains, but also reports the BA.4 evolution branch on July 6.

In terms of refining, there are 5 strains under the BA.2 evolution branch, including BA.2.3, BA.2.12.1, BA.2.38, BA.2, BA.2.2; There are 4 strains, namely BA.5, BA.5.2, BA.5.1, BA.5.2.1.

According to the information published by the Health Commission of various places, the correlation of this epidemic is not great, and the source is mostly foreign countries and regions.

Shanghai BA.5.2.1 mutant strain is an overseas entry -associated infection. 4 variation strains are inbound closed -loop management personnel and the BA.5.2 mutant strains in Xi'an also come abroad.

There is not much difference between viruses

Although these strains have different names, if they belong to the same strain, the actual differences are not large.

Jin Dongyan, a professor and virusist at the School of Biomedicine, University of Hong Kong, said that from a structural point of view, the differences between BA.2.12 and BA.2 are very small, with only 2 amino acid positions, so the basic characteristics are similar, including communication Ability and immune response. The Lanzhou epidemic was Omikon BA.2.38. It was discovered in India on January 7, 2022, but it was not spread globally. India.

According to the announcement of the Indian SARS-COV-2 Genomics Alliance, the mortality and hospitalization rate of this mutant strain did not increase. After entering June, the dynamic disease mortality rate at 7 days was at a low value and was relatively stable, remained at about 0.2%.

Chengdu is Omikon BA.2.12.1. It was detected in the UK on March 23 this year. Since then, it has spread rapidly in the United States and has become the main poison. 4), then replaced by BA.5.

According to data from the US CDC, BA.2.12.1 spreads faster, 23%-27%higher than BA.2.

However, the mortality rate has not improved significantly. When it is the main strain (May to early June), the mortality rate of the United States is relatively low, between 0.2%and 0.4%, but only two months ago only two months ago (March 21), the peak of mortality in the United States is as high as 2.81%(BA.1, BA.1.1 is the mainstream strain).

In the same way, many strains under the BA.5 mutant strains are also minimal.

In comparison, the differences between BA.4, BA.5 and BA.2 are slightly larger, and there are 3 changes in amino acid positions. Therefore, the spread of BA.5 is faster than BA.2, but the mortality rate and hospitalization rate are not much different from BA.2.

It is worth noting that no large differences also indicate that the pathogenicity of BA.5 has not weakened.

Member of the National Health and Health Commission medical institution infection and control of the Expert Committee of the Infection and Control of the National Health and Health Commission, Gao Xiaodong, deputy director of the Infectious Management Department of Zhongshan Hospital affiliated to Fudan University, said that if large -scale infections occur in BA.4 and BA.5 mutations, for the elderly with basic diseases, for the elderly with basic diseases, Still fatal.

Therefore, in addition to the original "three -piece set" and "five more", Gao Xiaodong advocated people to actively implement the "new epidemic prevention three -piece set" -miri regular measurement of acid, vaccination new crown vaccine, and active scanning code.

Source: Shangguan News, CCTV News, Beijing Daily

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