Is the two -metal dual -胍 outdated? Is it better for the effect of reducing sugar?

Some time ago, in the 2022 version of "ADA/EASD: Type 2 Diabetes Hypergly High Globe Management Consensus (Draft)", more recommended GLP1 receptor agonists and SGLT2 inhibitors are used as drugs for treating type 2 diabetes. It is rarely mentioned, so many friends asked Huazi, when he was treated with type 2 diabetes, was the two -two dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -doubles?

Hua Zi said that in the study of diabetes, it was found that the two new hypoglycemic drugs had a stronger protection effect on organs, so they received more recommendations. However, the two -meta dual -dual -duplex has not been eliminated. In the treatment of type 2 diabetes, the two -meta dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -dual -duplex is still a safe and effective oral hypoglycemic drug.

Moreover, the new round of national drugs are purchased, and the compound preparations of the two -metal dual -two and Vigerine are also in the directory, indicating that the dual -dual -dual -dual -dual -dual -dual -dual -to -line hypoglycemic drugs are not exited.

1. "Lao Dang Yi Jiu" Erjia and Double 胍

Since being discovered, the second and double -dual -dual -cymbals have been the first choice for type 2 diabetes. Moreover, after decades of verification, the hypoglycemic effect of the two -meta dual -dual -dual -duality is significant, and the adverse reactions are low. In the guidelines for diabetes in various countries, it is recommended that as long as there is no taboos, the two -metal doubles should always be kept in the treatment plan for patients with type 2 diabetes.

Even if there is a hypoglycemic drug such as the GLP1 receptor agonist and SGLT2 inhibitor, the two -meta dual -dual -duplex is still the first choice for patients with new diabetes, and the effect of hypoglycemic is still reliable. It's just that the former has a slightly strong protective effect on the heart, kidney and other organs, and is more suitable for patients with long diabetes.

Second, hypoglycemic rookie Vigerine

Vigerine is an efficient selective di-peptide-peptidase 4 (DPP-4) inhibitor that can delay the metabolism of the pancreatic hyperglycemic peptide 1 (GLP1) in the human body. GLP1 is an intestinal -promoting insulcation hormone produced by the human body, which can stimulate insulin secretion according to the level of blood sugar value.

The natural GLP1 has a short role, and it will be survived by DDP-4 in a few minutes after generation. Vigerine inhibits the role of DPP-4, which can extend the stimulus of GLP1 on insulin secretion. And when the blood sugar value is too low, GLP1 will not play a role, there is no risk of hypoglycemia, and the safety is high.

Third, the effect of reducing sugar after combined with medicine is stronger

From the perspective of the pharmacological mechanism, the two -ahead and Vigertin can be able to complement each other after use.

Two -dual -dual -tadpoles can improve insulin resistance, increase the use of tissue's utilization of glucose, reduce the output of liver glycogen, inhibit the intake of glucose cells in the intestinal wall, and have no significant lower blood sugar effect on normal people. Essence Vigerine can promote the secretion of insulin according to the blood glucose value.

When the two -meta dual -dual -dual -dosage reaches the best treatment dose, when the blood sugar is still not controlled, Vigerine can be used to further control blood sugar, and there is no risk of hypoglycemia, and the adverse reactions are less.

Moving the two into compound drugs can improve the compliance of patients' medication and avoid the failure of treatment caused by missed drugs. In addition, after entering the national collection of reciprocating records, the price of the two -meta -and -two Vigertine will be significantly reduced, and the cost of medication for patients will be significantly reduced.

To sum up, the two -metal dual -dual -dual -dual -dual -dual -dual -dual -duplex is still the first choice for patients with new types of diabetes. When the two -meta double -dual -dual -dual -reached the best treatment dose, if the blood glucose has not yet controlled the standard, it can increase the combined medication of Vigerine and further control blood sugar. You can also choose the dual -dual -pyramid Vigerine compound drug, simplify the medication process, improve the compliance of medication, and better control blood sugar.

Drugs need to be used under the guidance of a doctor, and have doubts about medication, please consult a doctor or pharmacist. I am a pharmacist, and welcome to follow me and share more health knowledge.

- END -