Pig heart transplantation was broken again, and the researchers successfully transplanted the pig heart into the two deceased's body.
Author:Pole news Time:2022.07.13
Jimu Journalist Li Lili
Intern Zhao Wenbo
Comprehensive Reuters, CNN, Associated Press and other media reports that Tuesday, local time, researchers said that the New York University Langni Medical Center has recently successfully transplanted the heart of genetically modified pigs into two patients with brain death. This means that scientists have taken an important step on the road to solving the shortage of human organ transplantation with pig organs.
The researchers introduced at the press conference that they conducted two experiments in June and July. At present, the heart function of the two patients with brain death is normal and there are no signs of exclusion.
Picture source: Associated Press
Earlier, the University of Maryland's medical team performed the world's first pig heart transplant surgery.
On January 7 this year, David Bened, a 57 -year -old American man, undergone the world's first pig heart transplant surgery at the University of Maryland. There is no exclusive reaction a few weeks after the operation. Although "artificial lungs" need to use "artificial lungs" to assist blood circulation, you can breathe yourself without a ventilator.
He died on March 8. In early July, the research team announced for the first time he died of heart failure. It is not clear what the cause of heart failure is currently unclear.
According to CNN, the objects of these two experiments are patients with brain death.
In June, the patient who underwent transplanted surgery was called Lawrence Kelly, from Pennsylvania, at the age of 72. After being announced to die, Kelly's family decided to donate the remains for this experiment.
Kelly and Wife (Picture Source: CNN)
Researchers purchased the pig heart required by experiments from other places. The heart made genetic modifications for many factors, such as regulating the growth of organs and reducing the chance of rejection of the receptor immune system.
After transplantation, the researchers performed a three -day test to monitor the heart condition.
The medical team said in the press release: "No signs of the early exclusion reaction were observed. After the use of standard transplants, there was no additional medical device support after using the standard transplantation, and the heart function was normal."
On July 6, the research team also performed pig heart transplant surgery at Alva Cap Arno, 64, New York City. Kapuano is also a patient with a brain. The surgery has achieved the same results.
On July 6, the operation site (picture source: Reuters)
Dr. Robert Monagemari, director of the University of New York University of Langeni Transplantation, said that such surgery helps researchers to more in -depth research on the degree of tolerance of the receptor to pig heart.
He said: "We can monitor more frequently to truly understand and fill all biological unknown."
Nader Moazami is the director of cardiac transplantation surgery at the Langeni Medical Center of New York. He is responsible for the leadership team to conduct research on non -human animal organs to surgical research in human remains.
Moazami said that using the body of the dead body to test animal organ transplantation is a new type of research method. In September last year, Dr. Moncore's team conducted the first relevant experiments. At that time, the team transplanted the kidneys of a genetically modified pig into a dead body.
"Although this research represents a step forward, there is still a long way to go to actually take a step forward, but there is still a long way to go."
He said that at present, the large restrictions are the length of the research. After the transplantation, the experiments can only evaluate the transplant organs and remains for 72 hours.
In addition, there may be significant differences in the reaction of the remains compared to the living person. Therefore, the experiment requires more research and longer assessment time to determine the tolerance of the transplant.
The demand for organ transplantation in the United States has been in short supply. As of July 7, there were 106074 people on organ transplantation, and 3,442 were on the list of cardiac transplantation. On average, 17 people died every day when they were waiting for organs.
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