The 5 -year -old and two -year -old medical records, the number of lives is dying, and the "Miracle Boys" is finally rescued

For medical professionals for reading reference

He won the heart of the people of the whole country

Written article | Yan Xiaoliu

Source | "Medical Community" public account

Oscar Saxelby Lee has broken the "British Record" twice in one year and is called "Miracle Boys" by the media.

In early 2019, more than 6,200 people donated blood and signed a letter of intent to create blood stem cells for him. This set a new record for such donations in the UK.

On March 3, 2019, thousands of people rushed from all over the United Kingdom to Woolst City, lining up in the rain, hoping to register and donate hematopoietic stem cells for Oscar. /SWNS

At the end of the same year, due to the development of the disease, he went to medical treatment overseas and received CAR-T treatment. Before him, there were no children in the UK who had done such treatment, and there were only a few cases worldwide.

As of the release of this article, Oscar has been "survived without cancer" for two and a half years. His mother, Olivia Saxelby, grateful: "Thank you all those who support Oscar. Without you, we cannot come today."

Oscar Saxelby Lee was taken in March 2022. /workers

In 2018, Oscar is 4 years old.

Parents found that the lively and active son "changed". I often feel bad and do not like to move. There will always be bruises in somehow. The appetite is getting worse and worse, and you are full.

On the eve of Christmas, Oscar was diagnosed: acute lymphoblag leukemia (ALL).

Oscar and parents before the illness. /SWNS

This is a blood malignant tumor that can account for more than 70%of children's leukemia. Children's period is the peak of the disease.

The combined chemotherapy is the basic treatment solution of ALL. There are data that this can be cured 80%of patients.

Oscar is that 20%.

The picture comes from BBC

As of March 2019, he had blood transfusion 20 times and completed the chemotherapy of 4 courses. But the condition is not optimistic.

Birmingham Children's Hospital, which provides him, said that cancer cells are still spreading rapidly, and Oscar needs to transplant hematopoietic stem cells. "As soon as possible. Find the time window of the donor, or only 3 months."

"We are running against time," Charity DKMS is committed to hematological tumor assistance projects. Sarah Gray, a spokesman for the agency, said that it is very difficult to find the matching object, just like the lottery. But the more people register, the greater the success rate of pairing.

At that time, Oscar just started to school. After learning the incident, he was studying the incident and decided to organize a "blood donation event" for him after learning the incident.

The president of the Elementary Primary School was interviewed by the media. The projection screen behind her read: "How many friends can you come today?"/BBC

The school joined hands with DKMS and converted the indoor sports field and the auditorium into a "registration center".

With the assistance of 80 volunteers, within 2 hours, more than 300 people came to register to complete saliva sample collection. These people also donated blood to Oscar on the spot.

The picture comes from SWNS

The event lasted 2 days.

During the same period, the Woolst City Hall and the University of Woolst also set up a poster to help Oscar. More than a thousand people come to register and sample.

After the statistics, this public welfare activity recruited 6,200 people to register and donate blood.

"We have done similar public welfare activities. When the number of participants is the largest, it is 2,200. The number of participants this time has doubled, and they are from all over the UK." DKMS said, "This little boy won the hearts of the people across the country."

The picture comes from DKMS

On March 29, 2019, Oscar's mother announced "good news" in social media officials: "Three people successfully paired! This greatly increased the opportunity of Oscar to live."

Benefiting from the Oscar that benefits from the event. DKMS found that as of the spring of 2020, five other patients with hematological tumors found the matching donors among more than a thousand good -hearted people and completed the transplantation.

Woolst Elementary School sends the collected saliva sample to the designated laboratory for DNA testing. /SWNS

Nearly two months after the event, Oscar completed hematopoietic stem cell transplantation.

The good times are not long. Three months after surgery, the doctor detected cancer cells in its bone marrow. One week later, the number of cancer cells increased by nearly tripled.

Doctors believe that traditional treatment is not very effective, and may be able to fight a car-T.

This is a cell immunotherapy. Doctors will extract immune cells with powerful combat capabilities -T cells from Oscar to genet in vitro, modify genetic materials, and introduce active molecules that can accurately identify tumor cells.

Then cultivate the "edit" cells. After breeding enough, it is lost to Oscar to kill cancer cells in its body.

During the hospitalization, Oscar participated in class activities through the robot "OZZYBOT". This robot can capture the expression of Oscar and make a happy, confused or sad look in the terminal. /Daily mail

On November 27, 2018, CAR-T therapy was performed by the British National Medical Insurance (NHS) approval. Related therapies can be used for recurrence or cure B -cell ALL under 25.

Oscar is a recurrence T cell ALL and is not within the scope of NHS authorization. Therefore, he cannot undergo related treatment in the UK. Mother Olivia went online and found that scholars in Singapore National University Hospital issued relevant papers.

After getting in touch with the hospital, Olivia learned that the therapy was "sympathetic therapy" in Singapore, with only one case of treatment experience. Moreover, 500,000 pounds (about RMB 4.02 million) -NHS said that they will not pay for overseas medical treatment.

After illness, Oscar often has bruises. /CNA

"The only hope for surviving is to go to Singapore to complete CAR-T therapy. We need everyone's support and goodwill so that Oscar can enter the next treatment stage." Oscar's parents initiate Internet crowdfunding. "Our situation is really bad. ","

Millions of people have generously unpubiated. Schools and enterprises at all levels and enterprises at all levels of Woolst have set up the "Oscar fundraising day" to go to the streets and raise funds for children.

With the assistance of a local family dedicated to the research of children's tumors, it was only 3 weeks, and the treatment fee was gathered.

The public welfare organization produces posters for fundraising. /Mirror

During the fundraising period, Birmingham Children's Hospital for the second hematopoietic stem cell transplantation for Oscar.

After surgery, he will have a short window period that can restore physical functions to a certain extent to complete long -distance travel.

The picture comes from mirror

In November 2019, Oscar and family arrived in Singapore. At this time, the little boy was thin and could not stand and walk.

The treatment process is very unsuccessful. He had severe side effects, vomiting, diarrhea, brain damage, and faint. Doctors constantly adjusted medication to help him survive treatment and reduce adverse reactions.

Time travels until January and April of the following year. Two examinations showed that cancer cells were not detected in Oscar. CAR-T has worked.

By the spring of 2020, Oscar was discharged.

Before leaving, Singapore National University Hospital collected his blood to collect immune cells and freeze as a backup resource for Oscar for subsequent treatment.

In May 2020, Oscar was discharged from the New University Hospital. /Daily mail

After returning to Britain, Oscar received several months of rehabilitation treatment.

In winter, he returned to the campus and learned to play football again. In the spring of the following year, he will practice basketball lessons every night.

As of the release of this article, Oscar's review results were good, and no signs of cancer cells were found.

"He is thinner and weaker than his peers. But seeing him always working hard and better than the day before, we are very pleased." Oscar's parents said.

"This is not only because of cure cancer. More importantly, we have not given up."

Pictures from the Internet

source:

1.OSCAR SAXELBY-Lee: Family Celebrates One Year Since Boy's Cancer Care. BBC

2.OSCAR SAXELBY-Lee Faces More Heartbreak Over Struggle for Australia Holiday. Worcesster News

3. Boy, 5, With Rare Cancer Faced 'Life or Death' Three Month Race Against Time. The Mirror

4.5-Year-Old Battling Cancer Finds Perfect STEM CELL MATCH After Over 10,000 People Comeward to Help. Meawwwww. Meawww

5.Record 4,855 people queue in the rain for hours to see if a step match for box, the battle, battling rare can his hands,

wx_fmt = pNG "data-nickName =" medical community "data-alias =" yixuejiezazhi "data-signature =" hi, finally wait until you have a good quality, level, caring!Providing you with reliable, useful, and valuable content is our way of existence. "Data-from =" 0 "data-is_biz_ban =" 0 " /> Source: medical community

School pair: Zang Hengjia

Editor -in -chief: Bi Beibei

- END -