The arm injection or healing genetic heart disease has proved that it is valid on animals

Polar news reporter Wang Liangliang Huang Jiaqi

Intern Zhao Wenbo

According to the "Guardian" reported on July 29, scientists will develop the world's first method of treating genetic heart disease by rewriting DNA. A method of injecting and treating genetic myocardial diseases will come out within a few years. Known as the "decisive moment" of cardiovascular medicine.

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It is reported that with the support of the British Heart Foundation (BHF), global experts from the United States, the United Kingdom and Singapore jointly established a R & D team from the United States, the United Kingdom, and Singapore to design a arm injection to rewrite the means of rewriting DNA to treat genetic heart disease. Come to save the lives of millions of people.

The team will test and design the treatment and designing the treatment and designing the precise genetic technologies of the base editor (Base Editing) and the PRIME EDITING for the first time in the heart to test and design the treatment of genetic heart disease. The goal is to make the defective genes silent. The research through animal receptor has proven that the technology is effective.

Nilsh Samani, Director of Medicine of the British Heart Foundation, said this is the decisive moment of cardiovascular medicine.

Genetic myocardial diseases are caused by heart abnormalities, which may cause heart failure or sudden death. About 260,000 people in the UK have this disease, which may cause sudden death at any age group. In the UK, 12 people under the age of 3 died of heart disease every week, which is often caused by genetic myocardial disease.

All people with genetic myocardial disease have 50%risks to pass defective genes to future generations. Family members with blood relationships may suffer from heart failure and need heart transplantation, otherwise they will die when they are young.

Professor Hugh Watkins, a professor at Oxford University, said that myocardial disease is "very common", and one of the 250 people around the world suffers from myocardial disease.

Professor Hugh Watkins, Oxford University (Picture Source "Guardian")

Waterkins said: "This is a very important moment for humans, which can relieve the patient's family's concerns about sudden death, heart failure, and heart transplant risk. After 30 years of research, we have discovered many genes and specific genes and specific myocardial diseases. Genetic defects and have mastered its working mechanism. We believe that gene therapy will start clinical trials in the next five years. "

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