Can you predict cancer if you look at the blood type?is this real?

We often see such a bridge in TV dramas: some people have major bleeding due to car accidents and trauma, insufficient blood sources in the hospital or unable to find matching blood sources, direct relatives (parents, children) are scrambling to donate blood for them ...

However, is the blood transfusion between direct relatives really reliable? Every year on June 14th is the World Blood donor day, then let's learn about blood today ~

1. Can relatives blood transfusion?

You know, in addition to the risk of blood transfusion, in addition to the risk of infection, the blood transfusion must also prevent various adverse reactions during the blood transfusion process.

Transfusion associated graft-versus-host display (hereinafter referred to as TA-GVHD) is one of the adverse transfusion reactions, and it is also one of the most serious blood transfusion complications.

Because the process of transfusion body blood is essentially the transplantation process of foreign objects, the cells of the foreign body will be transplanted to the main body of the host. The transplant will inevitably accompany a series Symptoms, once TA-GVHD occurred during the blood transfusion during the report at home and abroad, there was no effective treatment method, and the mortality rate of the blood was more than 90%.

The pathogenesis of TA-GVHD is mediated by lymphocytes in the blood, migrating and proliferating in the patient's body, and then attacking and destroying the severe immune response of the patient's body.

In simple terms, the lymphocytes in the blood in the blood in the blood are mainly anti -passengers, a large number of proliferation, and the severe adverse reactions caused by the blood in the body and tissue of the blood.

Is this TA-GVHD relationship between blood transfusion between relatives?

The relationship is very close!

The probability of TA-GVHD's blood transfusion complications in relatives is much higher than non-relatives. Especially the first-level relatives, that is, the incidence between parents and children is 11-21 times higher.

Therefore, in order to avoid complications, blood transfusion must be eliminated to the greatest extent.

However, with the continuous development of medical technology, special medical equipment can be treated with lymphocytes (blood irradiation) for blood, and the treatment of blood can be safely lost to their own direct relatives.

2. Can the blood type with saliva?

Yes, the appropriate amount of saliva can get the blood type results with a certain experiment.

As early as the early 1930s, foreign scientists discovered that in the saliva and other secretions of most people, it contains the same substance-ABH of the same substance as the red blood cell ABO blood type antigen. One is used in the field of forensic medicine, but it is rarely used for clinical and daily blood analysis.

With the advancement of scientific and technological and medical development, the blood type of saliva detection can be easily achieved through genetic testing: the prosecutor extracts the oral cells falling off in the saliva through a certain method, and after expanding its genetic information The DNA molecular information in the cell can be analyzed and judged, and the blood type type of the subject can be obtained.

3. Isn't it O -type blood?

The Chinese Academy of Sciences Shanghai Insect Museum has experimented with this:

This experiment from the Chinese Academy of Sciences chose a total of 60 volunteers. Before the experiment, the blood type was detected for each volunteer, and then the volunteers cleaned their hands with clean water to ensure that volunteers had no sweat and odor. During the experiment, the volunteers uniformly wear pink plastic gloves, and open a 4 cm mouth on the back of each glove. Volunteers extend their left and right hands into the mosquito cage twice. The number of tattoo mosquitoes (commonly known as flower feet mosquitoes) stays on the back of the volunteer's hand.

The results showed that in an environment with a temperature of 26 ° C-28 ° C and a humidity of 60%, the number of stays on the back of the volunteer's hand was different. Blood.

On the surface, it looks like type B blood than type O blood. In fact, the "most mosquito" type A blood volunteer and "the least recruited mosquito" Blood volunteer are favored by mosquitoes. Half a few times, this shows that the chance of recruiting mosquitoes at different blood types is similar.

Therefore, the goal of mosquito selection is not through the blood type.

Some experts point out that mosquitoes are looking for prey, which mainly depends on the strength of the human body to send "signal" to mosquitoes. The strong "signal" spreads through the air, which is conducive to the long -range trace of the prey. The "temptation smell", in addition, the mosquito also has a soft spot for the prey of dark clothes.

4. Can the blood type predict the disease?

As early as 1953, there was a study of blood type antigen A and gastric cancer.

In 1960, there was a literary report with ABO blood type and several malignant tumors, indicating that there is indeed some connections between the ABO blood type and the disease;

In recent years, it has been reported that domestic people with hypertension, diabetes and gastric cancer, and multiple people with multiple neuritis, acute spinalitis and periodic paralysis are mostly A blood type;

Some studies have shown that type A blood people are relatively susceptible to new crown pneumonia;

Type B blood people are more susceptible to pathogenic pathogens;

The incidence of esophageal cancer, cardia cancer, and prostate cancer in type O blood people is higher, but the probability of blood embolism and arteriosclerosis is low.

Although there are more and more research on the correlation between the blood type and the disease, it is mostly on the discussion of the statistical results, and there is no discussion of the relevant mechanism. In fact, there are many factors that affect the occurrence of the disease. one of. 5. What are the scarcity?

Since Karl Landsteiner discovered the ABO blood type system in 1900, MNS and P blood type systems were discovered in 1927. After the application of indirect albumin technology in 1945, more red blood cell blood type systems have been discovered.

With the development and application of molecular biology technology, in 2010, humans have found 30 red blood cell blood type systems. With the rapid development of genome sequencing technology, five new red blood cell blood type systems were officially named in 2020 alone. As of June 2021, a total of 43 red blood cell blood type systems were determined.

When it comes to rare blood types, there are many more rare blood types besides RH negative blood (panda blood)!

For example, as early as 1952, it was first discovered the extremely rare "Mumbai blood type" in Mumbai, India. The ratio of people with this blood type in the people in our country was only one hundred thousandths. So far, there are only about 30 cases in my country. Reports related to this blood type.

There is no H anti -antigen in the human body of Mumbai's blood type. Whether it has an equal genes of A and B blood types, its A antigen and B antigen cannot be synthesized. People with this type of blood type cannot accept any blood transfusion of the blood type of non -non -Mencius.

There are still many unknown things about the blood waiting for humans to explore the secrets. Because of its particularity and complexity, the blood can still not be artificially manufactured so far. It can only rely on healthy people to donate freely!

June 14, 2022 is the 19th World Blood Donation Day. If you want to see the popular science article, you can take precious time to bravely go to the blood donation car! Let's do the "big hero" to save others' lives together!

references:

[1] Hu Derong. The chance of recruiting mosquitoes at different blood types [n]. Health News, 2012-08-08 (002).

[2] Xu Hua, Zhang Jianeng, Xing Hexiang, Tan Yingxia, Zhang Yangpei. ABO blood type and disease research progress [J]. China blood transfusion magazine, 2008 (03): 220-222.

[3] Yang Dong, Chen Qing. New progress in the research of red blood cell blood type system [J]. Clinical blood transfusion and test, 2022,24 (02): 137-141+146.

Experts in this article: Song Yingwei, the technician of the first medical center of the General Medical Center of the General Hospital of the People's Liberation Army

Review of this article: Wang Deqing, doctoral supervisor, chief physician of the First Medical Center of the General Hospital of the People's Liberation Army General Hospital

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