The first domestic new crown special medicine was officially launched, and the price is less than 10,000 yuan

On July 8th, at the new crown and antibodies Ambellipab and Romi Siwei's combination therapy online commercial listed media communication meeting, Luo Yongqing, president of Teng Shengbo Pharmaceutical and General Manager of Greater China The therapy is still effective for the Omikon mutant BA.4 and BA.5, and announced the domestic pricing of this drug -basically within 10,000 yuan.

On the day ago, Teng Shengbo Medicine and its holding company Teng Shenghua announced that its new crown and antibody Ambellab and Romi Siwei's combination therapy was launched in China. The first batch of antibody drugs has achieved commercial Play. The medicine is also the first approved domestic new crown medium and antibody combination therapy drug.

At present, BA.4 and BA.5 of Omikon is setting off a wave of infection worldwide. On July 6, the Prince of the WHO Tan Desai said that BA.4 was detected in 83 countries and regions, and BA.4 was detected in 73 countries and regions. At present, BA.5 has replaced BA.2 to become the main poison in the world. The latest global new crown epidemic weekend announced by the WHO shows that the number of global new crown cases has increased for the fourth consecutive week, reaching the highest level since March this year.

The virus is constantly mutated. Whether the first domestic new crown special medicine can continue to "adapt", becoming the most concerned issue in the industry. "As a result that I just got yesterday, Anbawei's monoclonal anti -anti -anti -anti -anti -antibody therapy showed a good effect of virus inhibitory in the Omikon mutant BA.4 and BA.5." Lu Hongzhou, the dean of the People's Hospital, introduced at the meeting that the laboratory's fake virus research showed that the drug inhibited by 90%of the BA.4 or BA.5 virus concentration is very low, which can meet the effective standards specified in the FDA.

Zhong Nanshan, an academician of the Chinese Academy of Engineering, also stated at the meeting that based on the observation of clinicians, the combined therapy can make the high virus load down rapidly within a relatively short time (2 to 3 days). High patients are very effective.

Why is this combined therapy facing the continuous mutation of the new coronary virus continues to be effective? Zhang Linqi, the head of the R & D team and a professor at the School of Medicine of Tsinghua University, revealed that all research and development pharmaceutical companies use the "antibody pair" to avoid virus escape, but the "antibody against the antibody" is particular. Boxing. Based on the refined research on the interaction of the entire virus and antibodies, the team finally screened the time and space of the virus inhibitory from 206 candidate antibodies to coordinate the "antibody pair" in the space and find the "best partner".

In which region can this combination therapy use medical insurance reimbursement? Regarding this issue that everyone is very concerned about, Teng Shengbo's medicine responded that since March 22 this year, many provincial and municipal medical insurance bureaus have successively incorporated the combined therapy of Anbawei's anti -resistance and Romi Siwei. Payment scope.

What can be used as a comparison is that another neutralized antibody Evusheld (Enbish), which has been approved to be listed, has also been used in the international medical tourism area of ​​Boao Le City, Hainan through relevant policies. The price of sex injection is 13,300 yuan, and medical insurance settings cannot be used.

"Neutral antibodies can make up for the lack of vaccine and small molecular drugs when they are used in immune fragile people." The chief medical officer of Teng Shengbo Pharmaceutical explained strictly that some of the people who are immunization are not suitable for vaccination For new crown vaccines, some of them may not produce sufficient antibodies even if they are vaccinated with their own immune response, and the vaccine cannot prevent the effect. For this part of the crowd, the injection and antibodies can produce a "immediate" effect.

According to reports, in addition to treatment, the combined therapy also has a prevention effect. "A keyword of neutral antibody is neutral." Yan Li said that after combining antibodies and viruses, the virus concentration and titer in the patient can be quickly reduced, and the infection rate will naturally decrease. At the same time, the virus cannot be infected with new cells again in a combination of antibodies, and the half -life is longer, which can further effectively block and reduce the risk of group transmission.

Source: Beijing Daily Client

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