Good mood: How to improve the efficacy of mental illness and reduce side effects?

Treatment of mental illness, drugs are effective and indispensable. However, some patients will encounter such problems during the treatment:

In the same disease, others feel that it is very useful, but it is not used on themselves, and some patients even have adverse reactions.

Why is there such a situation of "different diseases and medicines"?

I have to mention an important variable here -genes. More and more studies have shown that it is an important factor that causes the effect of drugs.

How does gene affect the efficacy and safety of drugs?

If you want to figure out this problem, please understand what the psychiatric drugs will go through the human body with good mood.

After the drug was sent into the mouth, it opened its long and wonderful journey in the human body:

The picture shows the internal process of different dosage drugs

First of all, it will enter the stomach along the esophagus, be decomposed into smaller particles in the stomach, and then continue to enter the small intestine. Most of the drug components will absorb blood through the intestinal wall.

Then, the drug component will reach the next stop with the blood circulation: the liver. Under the processing of liver metabolic enzymes (such as CYP450 enzymes), some drug components will fail or weaken the activity. The remaining drug ingredients will be carried on a blood circulation ride, which will be transported to various tissues and organs of the whole body, and then combined with the target target. And then play a role.

When the drug falls off from the target organs, it will be carried on the car and enter the liver again, and then some drugs will be processed again by the liver metabolic enzyme, and eventually discharge the body in the form of urine.

The cycle of the experience of drugs and metabolic products from "liver -whole body -kidney" continues until it is completely cleared or filtered out of the body.

This is the process of drugs in the human body.

In this process, drug metabolic enzymes, drug targets, and transit proteins play an important role. If the related genes of these proteins are encoded, it will cause changes in metabolic and efficacy.

For example, if the drug enzyme involved in drug metabolism occurs, it will significantly affect the changes in the concentration of blood, which will cause the consequences?

Drug metabolism is too fast, which will lead to the short retention time of the drug in the body, resulting in poor curative effect. Instead, if metabolism is too slow, it may cause drugs to accumulate in the body, cause too high blood drug concentrations, and induce adverse reactions.

Now, do you understand why there is a situation of "different diseases and medicines"?

How to break the genetic password to find "precise drugs" faster?

Many patients' friends may ask that since genes are the main factor that causes drugs to vary from person to person, is there any way to understand our gene sequences and help them choose better medicines and medications?

Of course! Drug gene detection can be performed.

Drug gene detection can understand the specific situation of genes related to the drug effects through blood, saliva, etc.

According to the test results, doctors can provide patients with more reasonable drug selection and treatment reference dosage, optimize and implement the medication plan. Patients do not have to repeatedly "test medicine" repeatedly, thereby reducing medicinal detours and saving medical expenses.

In addition, the drug gene test can also fundamentally prevent the occurrence of adverse drug reactions, maximizing the patient's pain and economic burden, rather than taking after remedial measures.

It can be said that the detection of drug genes has changed the treatment status of thousands of people and one medicine, and truly realizes "tailoring of body tailoring" and "medicine for people."

Related studies have shown that the detection of pharmaceutical genomics can increase the response rate of the disease 2.26 times, increase the treatment relief rate by 2.5 times, effectively reduce the incidence of adverse reactions, improve the symptoms improvement rate, and improve the quality of life of patients.

If you have the following situations, it is recommended to do drug gene test:

● The effect of using a certain drug has always been unsatisfactory, and the condition control is unstable;

● There are obvious side reactions after using the drug;

● When other drugs need to be used;

● Drugs that are onset for the first time or are intended to induce severe adverse reactions, such as chlorobine, Ramozine, and Kamasi equal;

● Some special groups, such as the elderly, pregnant mothers, etc. Because the activity of drug metabolic enzymes may be reduced with increased age, some hormones unique to pregnancy can lead to enhancement of drug metabolic enzymes.

At present, a good mood platform has a highly cost -effective product: Ning Xinan's psychiatric medication gene detection. Compared with other genetic testing products, it has the following 4 advantages:

01

The detection is comprehensive, the prediction is accurate

Ning Xinan adopts the detection method of the whole genome genome (WGG), with a total detection site of more than 700,000, covering ADME (absorption, distribution, metabolism, excretion) of up to 16,000 or more The type of coverage is extremely high, and the report is given in combination with statistical methods.

The common detection methods of other genetic testing products on the market are flight mass spectrometry detection, which is often detected for genetic points that are already clearly effective. The coverage of the coverage is very limited. The type of division is also very limited.

02

Intelligent report, accurate and efficient

Ning Xinan's genetic testing report is fully interpreted by digitalized means, and the source of testing and interpretation of evidence is the China National Drug Administration (NMPA), clinical drug genetic implementation alliance Authoritative clinical guidelines such as DPWG), American Drug Pharmaceutical Administration (FDA) and Pharmgkb online databases. For different types of therapeutic drugs, the report gives advice to the choice of drugs, which can help us choose to treat the drug stably, so that "starting correctly and increasing the cure rate of disease".

03

Disease coverage is full and cost -effective

Ning Xinan's genetic testing and testing scope covering 9 major types of diseases including mental and psychological schizophrenia, depression anxiety, multi -phase, bilateral, sleep disorders, and epilepsy, and 80 related therapeutic drugs.

Many patients' friends may say, what's the disease, just check all the genes corresponding to the disease. Why should you check the 9 categories and cheat money? Intersection

It has been said in previous articles that the probability of common diseases of mental illness is relatively high. For example, patients with depression often have anxiety symptoms; insomnia can be seen in most patients with mental psychological disorders; anxiety……

When a patient develops a certain disease, it may also be accompanied by the symptoms of other diseases. To treat the body and spirit, you must think about it in all aspects.

04

It is easy to operate, you can do it without leaving home

After buying gene testing products on a good mood platform, we will mail you to the test box. You can send us back to us according to the operation description of the operation. You can receive the test report online after receiving 5 working days of the sample. Is it so easy? Let's do a genetic test! Understand your own genes, choose the medicine and dosage that suits you, avoid the use of drugs that may produce serious side effects, so that you can restore your health faster and better, and return to a happy life ~

Reference materials:

[1] Yang Linyan, Yang Xu, Fan Dongmei, et al., Etc. The common genetic polymorphon sites and their detection methods of the Chinese population [J]. Molecular diagnosis and treatment magazine, 2017, 9 (5): 358-363.

[2] Yang Jinbin. The impact of drug gene test on individualized medication [J]. Grass -roots medical forum, 2017, (7): 3..

[3] Chen Yan, Liu Wei, Fang Lizhen. Drug -related genetic testing of the guidance of clinical reasonable drug use [J]. Health must read, 2019, (18): 75.

(Article source: Photo.com)

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