Successfully improved the age of DNA methylation, and the new ideas of anti -aging research on traditional Chinese medicine

"Can we stop ourselves from aging?" This is one of the 125 scientific issues in the world released by Science "Science", and it is also a hot spot in the field of life sciences.

On June 27th, at the 2022 China Big Health Industry (Wuzhen) Forum, Hou Yunlong, head of the State Key Laboratory of Chinese Medicine Studies and Innovation Traditional Chinese Medicine State Medicine, shared the new research ideas of anti -aging: Intervention, improve the age of DNA methylation, and achieve the purpose of delaying aging.

According to reports, Hou Yunlong and his research team found that by continuous administration of eight sons to nourish the kidney for two months, the aging mice of 60 weeks (equivalent to 50 years old) can be reversed to 40 weeks (equivalent to a person 37 years old To. It is worth noting that this is my country's first compound drug research to use Chinese medicine to improve the age of methylation. Related research is being carried out at Shanghai Ruijin Hospital and will disclose the early results in the near future.

"The level of methylation predicting the physiological age is one of the internationally recognized most authoritative evaluation methods." Hou Yunlong introduced that aging is a process of gradually developing in accordance with the life cycle. Armalization of biological genomes will change, which will affect the expression of each gene and show aging performance. The aging itself is not terrible. It is terrible that a series of diseases burst out of aging, such as tumors, heart disease, vascular atherosclerosis, osteoporosis, and degenerative lesions of the central nervous system. Therefore, it is generally selected for the treatment of multi -way and multi -target. The traditional Chinese medicine has the characteristics of overall regulation. Whether it is small molecular drugs or compound drugs, it has a very clear and wide range. The study of Chinese medicine against aging has a long history, and has a wealth of classic celebrities to provide the theoretical basis for research reference.

Therefore, under the guidance of the "Chinese Medicine Listing Theory", in 2020, Yiling Pharmaceutical established the first domestic aging research and anti -aging drug research and development platform, using existing system biology theory to explain the theory of Periodism and the theory of gas in the brain aging The theoretical basis and guidance value of multi -system aging such as blood vessel aging, bone aging, and other systematic aging are very important for promoting systematic cognition of aging and intervention targets, and ultimately realized the development of innovative drugs for the treatment of aging -related diseases.

Hou Yunlong introduced that the platform is currently operating well, including the staged results of the research on system aging for innovative Chinese medicines 'eight -son tonic kidney capsules'. Anti -aging diseases such as osteoporosis during menopamental periods and atherosclerosis.

In the International Diseases Code (2018), it is clearly stated that aging has been regarded as a treatment that can be treated. More and more enterprises and scientific research institutes have participated in it to explore the research of anti -aging drugs. At present, for anti -aging, nearly ten kinds of mechanism mechanism research from different perspectives such as pathology and physiology has also been proposed.

"Most of the previous mainstream views believed that aging is like a class of diseases that do not have clear causes, such as Alzheimer's disease. Because I don’t know the cause, there is no way to intervene in the real sense," in Hou Hou, "in Hou Hou Yunlong's view, "Now the medical community has adjusted the direction of the aging itself, and has begun to pay attention to some diseases related to aging. By looking for markers related to aging, regulating the logo to achieve anti -aging purposes."

In the future, with the continuous deepening of anti -aging research, the market prospects for anti -aging medium medicines represented by the eight -son tonic. Hou Yunlong said, "We will continue to work as a guidance for the theory of traditional Chinese medicine, to continue to inject the driving force for the development of biomedicine, provide new options for delaying premature aging, and filling drug treatment based on anti -aging factors. Blank, improve the health of national health. "

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