How to treat and prevent this disease in Guangdong's new number in the country?

Eliminate hepatitis B and far away

According to the latest data on the incidence of hepatitis B in the "2021 China Health and Health Statistical Yearbook", the number of new hepatitis B nationwide in the country has increased significantly in 2017. However, in 2020, a significant decline in declined to 900,000, and the number and incidence in many provinces across the country declined. It can be seen that in the past two years, the prevention and control of chronic hepatitis B (referred to as "slow hepatitis B") has achieved good results in the past two years. Dao Yuan, so it still needs to adopt more effective strategies in the prevention of hepatitis B prevention and hepatitis B. Guangdong Province still ranks first among the number of new hepatitis B people in the country. According to data from the State Centers for Disease Control and Prevention, the number of antigen -positive positives on the surface of hepatitis B in my country is as high as 87 million. If you do not accept standardized examination and treatment, a considerable part of it will gradually evolve into liver cirrhosis and even liver cancer.

The 10 provinces with the largest number of people with hepatitis B accounted for 70.4%of the total number of new issues, and the region where the patients are located are more concentrated.

The top 10 provinces in the number of hepatitis B in the country have changed partly compared with 2019. The top 10 in Jiangxi Province, and Sichuan Province has become one of the top 10 new number of new people in the country in the country; Guangdong Province is still ranked 1st in the country's new number of hepatitis B The ranking ranking ranks 3rd in the country.

The number of new people in Sichuan, Guangdong, and Guangxi has increased slightly, and the number of hepatitis B newly issued in the remaining seven provinces has decreased compared with 2019. In addition to Sichuan Province, the incidence of other nine provinces also shows a downward trend compared to 2019 Essence

The number of new hair in Hubei, Hebei, Henan, and Shandong decreased significantly, all of which exceeded 10%; the incidence of Hubei, Henan, Hebei, Shandong, and Fujian decreased significantly, all of which exceeded 10%.

The above data source- "2021 China Health and Health Statistical Yearbook"

Answers of hepatitis B science popularization knowledge

Q

How is hepatitis B virus contagious?

A: Hepatitis B can spread through blood, maternal and infant transmission, and sexual contact. As my country conducts strict screening of blood donors, the condition of blood transfusion infection infection hepatitis B virus is very rare. Maternal and infant transmission includes the blood or body fluids of the positive mother of the hepatitis B virus during pregnancy, during childbirth, and postpartum, which causes hepatitis B virus infection. With the use of hepatitis B vaccine and combined immunoglobulin, the transmission of hepatitis B maternal and infants during delivery is greatly reduced, but it should be paid attention to infection during pregnancy, especially pregnant women with a high amount of HBV DNA virus.

Another case is that there are actually a large number of hepatitis B virus in semen and vaginal secretions infected by hepatitis B virus. If the husband and wife or the sexual life does not have hepatitis B surface antibodies, that is, if there is no hepatitis B protective antibody, there is no condom without condoms. When protecting sexual behavior, it is also easy to infect hepatitis B virus. In particular, I want to tell you that hepatitis B virus contaminates or incompletely disinfection, such as shaver, fingerprint, dental treatment, eyebrows, tattoos or public needles (venous drugs), and public toothbrushes. AIDS virus infection is a high -risk factor.

Q

What are the complications that may be caused after slow hepatitis B virus infection?

A: Common complications include liver cirrhosis, liver cancer, liver coma (hepatic encephalopathy), esophageal stomach vein chip -ups, gastrointestinal bleeding, ascites, liver and kidney syndrome, etc. About 120,000 patients in the country die from the hepatitis B virus (HBV) chronic infection of the liver cancer each year, and it is currently the second largest mortality tumor in the world.

Q

Does slow hepatitis B need long -term treatment? Can hepatitis B cure?

A: Yes, slow hepatitis B is the abbreviation of chronic hepatitis B. It belongs to a chronic disease and requires a regular treatment of long -term anti -hepatitis B virus. However, some patients have achieved clinical cure for drugs under the guidance of experts, that is, the disappearance of hepatitis B surface antigen (HBSAG) after treatment, and/or or appearing hepatitis B surface antibody (anti-HBS). Patients who have reached clinical cure, first, do not need to take medicine, but still need to be checked on a regular basis; second, the opportunity to develop into cirrhosis or liver cancer will be greatly reduced in the future. If you want to know clearly, please consult an expert.

Note: Do not stop drugs at will, change medicine or reduce medication, etc. At the same time, check at least half a year. Note: Please consult the experts before stopping the drug and change the medicine.

Q

Which groups have a big chance of clinical cure?

A: Related research data results show that the characteristics of clinical cure patients are expected to achieve:

Light age

female

HBEAG negative

Before the treatment, the level of HBSAG is low, usually lower than 1500IU/m

Hepatitis B virus load replicates medium degree

During the treatment process, HBSAG fell faster. For 3-6 months, HBSAG fell more than 10 times

ALT high level during the baseline or treatment process

History of Hepatitis B Family

Q

How to achieve clinical cure?

A: At present, there are many clinical schemes to help patients with hepatitis B to achieve clinical cure, such as initial interferon of nucleoside (acid) analogs, or schemes such as nucleoside (acid) analogs and interferon. Show: HBEAG negative, patients with HBSAG below 1500IU/ml receive nucleoside (acid) antiviral drugs combined with long-acting interferon, or sequential long-acting interferon, etc., the clinical cure rate can reach 30%-35% Essence In summary, hepatitis B clinical cure is not out of reach. Some liver friends have the opportunity to obtain clinical hepatitis B clinical cure. The specific plan should be dependent on the individual conditions of the patient. Compared with oral drugs, interferon therapy is high in the short term, and the side effects are relatively obvious, and not all patients are applicable. Experienced doctors will choose the appropriate treatment plan according to the specific situation of the patient, and reasonably cope with the various side reactions occurred in the patient's treatment. It is recommended that the relevant treatment needs to be carried out under the guidance of a specialist infected. Q

What are hepatitis B big three yang and small three Yang? Is the big three yang more serious than Xiao Sanyang?

A: The so -called "hepatitis B and the Three Yangs" refers to the immune indicators of patients with hepatitis B virus in chronic hepatitis B or hepatitis B virus carrier, that is, hepatitis B surface antigen (HBSAG), hepatitis B antigen (HBEAG), hepatitis B core antibody (anti -HBC HBC) ) Three positives. In the hepatitis B two -pair checks, the three indicators of 1, 3, and 5 are positive. The so -called "hepatitis B Xiaoyang" refers to the three positives: hepatitis B surface antigen (HBSAG), E antibody (anti -HBE) and core antibodies (anti -HBC), which is the three indicators of 1, 4, and 5 in the second -half check indicators of hepatitis B second -to -half examination indicators Essence

The severity of chronic hepatitis B virus infection or chronic hepatitis B depends on the degree of liver inflammation and fibrosis, whether it is sclerosis and complications. Generally speaking, hepatitis B Xiaoyang has a longer course of disease, the proportion of cirrhosis, and even liver cancer, but comprehensive assessment is required. Therefore, for those who are infected with hepatitis B for a long time or age (over 30 years old), it is recommended that hepatic tissue puncture+pathological examination under ultrasound examination is still a "gold standard" that clarifies the lesion. Because this is a creative operation, you usually need to be hospitalized for 3 to 5 days.

Q

Can't heal Mother B the mother get pregnant?

A: You can get pregnant. However, regular examinations must be checked during pregnancy to avoid hepatitis B or hepatitis. If hepatitis B virus is high or has a family history of hepatitis B, you should also pay attention to avoid transmission to your baby. Please consult an expert.

Q

Can hepatitis B mothers give birth to healthy babies without hepatitis B?

A: It is completely possible. At present, my country conducts hepatitis B, hepatitis C, syphilis, and AIDS on all mothers in China. "". The currently used hepatitis B blocked oral drugs is safe.

Q

Do you need to check it regularly after infection with hepatitis B virus? How long is the frequency of inspection? What projects do I need to do?

A: Hepatitis B positive, most of them have no conscious symptoms. Once some patients are checked, hepatic cirrhosis and even liver cancer. Therefore, for those who carry chronic hepatitis B, hepatitis B virus, and those who take antiviral drugs for a long time, regularly detect indicators related to hepatitis B-liver function, hepatitis B and a half, hepatitis B virus load (HBV-DNA), A fetal protein (AFP), abdominal abdomen B -ultrasound, liver elasticity, liver fibrosis indicators are crucial! It is recommended to check at least once every six months. For example, special circumstances such as initial initiative, application interferon, liver function abnormalities, HBV-DNA horizontal rebound, cirrhosis, and other complications, etc., the relevant examination is added in a timely manner according to the doctor's suggestion.

Reminder: The Department of Infectious Diseases of Zhongshan Seventh Hospital has rich experience in the clinical hepatitis B clinical treatment and hepatitis B maternal and baby blocking. We have been acting for the health of the liver. We have been acting. If you have any questions, you are welcome to go to Zhongshan to go to Zhongshan Outpatient consultation of the Seventh Hospital of Infectious Diseases.

Department introduction

Department of Infectious Diseases (referred to as infection) of the Seventh Hospital of Sun Yat -sen University (referred to as infection department) is the vice chairman of the Guangdong Medical Association Infectious Disease Branch/Vice Chairman of the Infectious Diseases Alliance of the Guangdong -Hong Kong -Macao Greater Bay Area, and the Guangdong Provincial Hospital Association Infectious Disease Management (No. 1 The first) and the deputy chairman of the Guangdong Medical Education Association Infectious Diseases (the first), which is also the unity of Shenzhen's suspicious liver disease and liver occupation specialist alliance and Shenzhen liver disease multidisciplinary alliance. At present, there are 11 doctors in the department, all graduated from Sun Yat -sen University or well -known medical colleges at home and abroad, including 1 doctoral supervisor, 3 master tutors, 3 doctoral medical, 9 master's degree in medicine, 2 doctoral students, 2 masters, masters, Four. Relying on Sun Yat -sen University, the department will build an infection and immune center, and the new hair infectious disease center, and will establish a "difficult and severe infection diagnosis and treatment center". In the future, the key areas of disciplines will be the clinical research of the diagnosis and treatment of infectious diseases and anti -microbiopathic drugs, diagnosis and treatment of anti -microbiopathic drugs, diagnosis and treatment of HIV infections and low immune functions, and the diagnosis and treatment of new infectious diseases.

Specialty diagnosis and treatment characteristics:

1. Hepatitis B maternal infant infection and blocking measures, women during pregnancy are combined with hepatitis and liver disease;

2. Various hepatitis/liver disease, fatty liver and alcohol hepatitis, cirrhosis and complications;

3. Repairing for fever: Various infectious diseases and rare diseases, especially the reasonable use of long -term unknown fever, causing severe infection/purulent hemiamal, and antibiotics. 4. Prevention and control and treatment of infectious diseases and new infectious diseases, such as bleeding fever, dengue fever, influenza, etc.

Outpatient information of infection:

● Outpatient time: every Monday to Sunday

● Outpatient location: Internal Clinic of Zhongshan Seventh Hospital (3rd Floor)

● Registration method: Follow the online appointment registration of the WeChat public account of Zhongshan Seventh Hospital

Expert doctor introduction

Director Chen Youpeng

Professor, doctoral supervisor/post -doctoral cooperative mentor

Doctor of Medicine graduated from Charité Medical College of Berlin University/Berlin University of Berlin. He is currently the director of the Infectious Disease Department of the Seventh Hospital of Sun Yat -sen University and Deputy Director of the General Medicine Teaching and Research Office. He studied at the University of Berlin/Berlin University for five years. The University of Mainz University Institute of Transformation of the Institute of Immunology and Beijing Union Hospital Infected Infectious Infertility House Researchers/Visiting Scholar. In 2020, he was awarded the excellent physician in Shenzhen, the anti -epidemic model of Guangming District, Shenzhen, and the advanced individuals of anti -epidemic in Shenzhen and Sun Yat -sen University. Member of the National Liver Health Promotion Expert Committee, National Hepatobiliary Disease Consulting Expert, National Experts from the National Difficulty and Critical Hepatitis Diseases, members of the Chinese and Western Medicine Society of Traditional Chinese and Western Medicine, member of the Liver Diseases Committee of the Chinese and Western Medicine Society, and the deputy deputy Chairman of the Chairman, Vice Chairman of the Guangdong -Hong Kong -Macao Greater Bay Area Infectious Disease Alliance, deputy chairman of the Guangdong Provincial Hospital Association Infectious Disease Management Committee (first session), and the deputy deputy Chairman of the Chairman, the Standing Committee of the Liver Disease Professional Committee of the Traditional Chinese and Western Medicine Society, the member of the Standing Committee of the Guangdong Medical Industry Association Infection Management Branch, the member of the Standing Committee of the Hepatitis Professional Group of the Guangdong Liver Disease Society, the member of the Guangdong Medical Association Infectious Science and Physician Branch (5th) Member of the Provincial Association for Infectious Diseases, Member of Guangdong Microbiology and Immunology Branch, experts from the AIDS Diagnosis and Treatment Group in Guangdong Province, and a director of the Special League of Liver Divine Hepatitis and Liver Plaza.

Good at: Hepatitis, liver disease/liver cirrhosis, fever treatment, purulent leather/severe infection, the diagnosis and treatment of AIDS and new infectious diseases, the vertical spread of hepatitis B mother and baby, and its blocking measures.

Outpatient diagnosis time: Monday morning (special needs outpatient), Monday afternoon, Thursday (Thursday morning/Thursday afternoon), Friday morning

Chairman Zhang Licap

Professor of Specialdo for Zhongshan Seventh Hospital

Doctor of Medicine, Master Student Tutor. Former Director of the Infectious Medicine Department of Sun Yixian Memorial Hospital (Second Hospital) of Sun Yat -sen University. Dr. Science (Major infectious Diseases), graduated from Sun Yat -sen Medical University, and studied with Professor Peng Wenwei from the famous infectious diseases; for two years at post -doctoral work at Osaka University in Japan and the National Institute of Microbiology, Japan. Former member of the China Medical Doctors Association Infectious Diseases and Parasitic Diseases Branch, Deputy Chairman of the Guangdong Medical Association Infectious Diseases and Parasitic Diseases Branch, Deputy Chairman and Secretary -General of the Guangdong Medicine Society of Traditional Chinese and Western Medicine, Guangdong Province, Guangdong Province Standing Committee Member of the Inspection Society, member of the Campaign Committee of the Guangdong Provincial Chinese Medicine Society. He has been engaged in the clinical, teaching and research work of infectious diseases such as viral hepatitis for nearly thirty years. He has presided over a number of scientific research topics such as "Research on Immunohistochemicals of Hepatitis Virus infection and Hepatocytal Carcinoma" such as the National Natural Science Foundation of the National Natural Science Foundation. The Ministry of Health's five -year system of “Infectious Diseases” (sixth edition), "Tropical Medicine" (1, 2), "Modern Infectious Diseases and Infectious Diseases", "Practical Liver" More than 10 monographs such as the Study of Diseases, the Study on Viral Hepatitis and the Compilation of the English -Chinese Molecular Biology Dictionary. Due to the outstanding achievements in the research of hepatitis and liver cirrhosis, it has won a number of rewards such as the Second Prize of Scientific and Technological Progress of the State Education Commission. A total of more than 40 professional papers have been published, and more than 10 postgraduate students are trained, including 1 foreign students.

Good at the diagnosis and treatment of infectious diseases such as viral hepatitis, cirrhosis, fever and diarrhea, etc., especially in the diagnosis and treatment of liver disease.

Outpatient diagnosis time: All day every Wednesday (Wednesday morning/afternoon)

Pi Sai male resident

Master of Medicine, graduated from Jinan University, worked in the HEINRICH-PETTE Institute and Leibniz Institute of Animal Virus in Hamburg, Germany. Participate in the study of provincial and municipal -level projects related to a number of mothers of hepatitis B pregnant, fatty liver, and publish chronic hepatitis B and chronic hepatitis C infection in pregnant women

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