Frequentine, at least 6 points!

For medical professionals for reading reference

Evidence -based medicine, reasonable medication

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Fluinizine is a selective calcium antagonist. It is widely used in the treatment of migraine pain, dizziness, and lack of blood supply to the brain [1,2]. How to apply Fluentirazine correctly? Let's follow the border medicine, let's take a look ~

Pharmacological effect

Fluinizine can prevent cell damage caused by the overload of pathological calcium caused by ischemia and other reasons. It has the effect of relieving the basal arteries and intramuscular arteries; it can increase the flow of small arteries and improve the circulation of the vestibular organ; it can block the pathological calcium of the pathological calcium of the nerve cells and prevent paroxysmal dehuminification, cells Discharge to avoid seizures; improve renal function; anti -histamine effects [1,2].

Indications and usage dosage

See Table 1 [1,2] for the indications and usage of fluinizine.

Table 1 Intersection and usage of fluidizine

medicine interactions

1. On the basis of the treatment of antiepileptic drugs, plus fluinizine can improve the effect of antiepile epilepsy [4].

2. Fluinizine combined with double other Stein can improve the blood circulation of the brain, increase the blood supply and oxygen supply of the brain cells and inner ear, improve the clinical symptoms of acute dizziness, the treatment of dizziness, vascular headache and tinnitus can increase the effect [5,66 ].

3. When combined with alcohol, hypnosis or sedative medicine, aggravate the sedative effect [2].

4. When applying with phenytoin sodium and Kamasiping, the blood concentration of Flinsulizine can be reduced [2].

Adverse reactions

The most common adverse reactions are sleepy and/or weak (20%), and weight gain (11%) may also occur. Occasionally depression and Parkinson syndrome [2,7-8].

4 cases are disabled

1. Acute cerebral hemorrhage.

2. Symptoms of depression, Parkinson's disease or other tainers.

3. Allergies to Fluinitizine or any auxiliary materials in this product.

4. Because this medicine can pass through the placenta barrier and can be secreted with milk, although there is no deformed and impact on embryonic development, in principle, women during pregnancy and lactation do not need this medicine [2].

You need to pay attention to these 7 points

1. Do not use the treatment of migraine acute period.

2. For the treatment of chronic dizziness for 1 month or sudden dizziness, the symptoms have not been improved after 2 months, and the medicine should be discontinued.

3. When used to prevent migraine, if no significant improvement is seen after 2 months of treatment, medication should be stopped. Even if the effect is significant, the medicine should be discontinued after 6 months of treatment, and the medicine should be taken again when recurrence.

4. In the process of medication, strictly control the dosage.

5. Because the nervous system of elderly patients is sensitive and the metabolic ability is weak, the amount should be reduced as appropriate.

6. Patients with liver dysfunction should be used with caution.

7. After taking the medicine, there may be adverse reactions of drowsiness, so drivers and machines should be used with caution; it is recommended to take this product before going to bed at night [2].

references:

[1] Xu Yunhong. The clinical application of Fulinine hydrochloride hydrochloride [J]. Chinese Medical Innovation, 2010, 7 (12): 191-192.

[2] Fluinine hydrochloride drug instructions.

[3] Ren Zhanxiu, He Qiu. The efficacy and safety of fluoricate hydrochloride in vestibular migraine prevention treatment [J]. Aerospace Medical Journal, 2021, 32 (11): 1350-1352.

[4] The clinical effect of Wang Shiwei. Fluinine to treat refractory pediatric epilepsy and its impact on the expression of multi-medicinal resistance gene (MDR1) -mRNA [J]. China Pharmaceutical Economics, 2019, 14 (8): 52-54.

[5] Cai Meiyuan, Xie Anping. Fluinine hydrochloride Capsule combined with metharodic acid Beatin tablets to treat benign dizziness clinical effects [J]. Shenzhen Chinese and Western Medicine Journal, 2022, 32 (6): 106-109: 106-109 Then, then, then

[6] Luodi. Perinine hydrochloride hydrochloride the treatment of tinnitus therapy for tinnitus [J]. China prescription medicine, 2018, 16 (3): 90-91.

[7] Xu Shuang, Xu Wei, Zhang Wei, Waiting. Fluinizine capsule safety analysis [J]. Heilongjiang Pharmaceutical, 2021, 34 (4): 820-822.

[8] The research progress of the Parkinson syndrome of Parkinson's Parkinson's syndrome caused by Shi Jiajia.

Do you still want to see what common medicinal methods and points of attention? Welcome to leave a message to tell the small medicine in the world ~

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Source: Medical Community

School pair: Zang Hengjia

Responsible editor: Song Kunlun

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