The more vitamin D is supplemented, the lower the risk of dementia?

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Clinical information, 1S touch

Epidemiological and scientific surveys show that there may be some of the same pathophysiological mechanisms of diabetes and vascular dementia (VD). The risk of dementia in patients with type 2 diabetes (T2DM) is 1-57 times that of ordinary people. [1-2].

Epidemiological studies have shown that vitamin D levels are related to dementia risks of the general population. Although the mechanism has not been fully clarified, it is generally believed that vitamin D may reduce the risk of dementia by reducing neuritis and vascular damage [2].

So, among the high -incidence T2DM patients, can Multi -dimensional D reducing the risk of diabetes -related dementia?

Source: Literature Screenshot

Tingting Geng et al. Published a paper in the PLOS MED magazine, which evaluated the correlation between the risk of vitamin D concentration and diabetes -related dementia in serum [3]. Let's take a look!

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references:

[1] VAGLATOS NT, ESLICK GD. Type 2 Diabetes as a Risk Factor for Alzheimer'sDisease: The Confounders, Interactions, and Neuropathology Association Withthiship [ EPIDEMIOL Rev, 2013; 21 (35): 152-60.

[2] Jiang Wei, Gao Fengrong. Vitamin D lacks related diseases research progress [J]. China osteoporosis magazine, 2014,20 (03): 331-337.

[3]Geng T, Lu Q, Wan Z, et al. Association of serum 25-hydroxyvitamin D concentrations with risk of dementia among individuals with type 2 diabetes: A cohort study in the UK Biobank [published online ahead of print, 2022 Jan 13]. PLOS Med. 2022; 19 (1): E1003906.

Source of this article: Clinical Decision Assistant

Author of this article: Boundary Xiaoshi

Editor in charge: Wen Jiaxin

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