There are new breakthroughs in the treatment of virus warts in CUHK!

On September 14th, the Journal of the American Medical Association Dermatology (Jama) sub -magazine "Jama Dermatology" was published online for the first time in the International of Southeast University's Affiliated Hospital. -The clinical innovation and treatment of fluoristidine treatment of virus warts. Wu Yan, the dermatology department of the CUHK Hospital, is the first author, and Professor Wang Fei, director of the dermatology, is the author of the communications.

According to Wu Yan, a dermatology department at the University of China, warts are caused by Human Papillomavirus (HPV) infection with keratin formation cells (the main cells in the epidermis). When the virus infection is infected with the base layer, the epidermis is thickened and excessive, and a weeks or months later become visible to the naked eye. About 40%of people are infected with human papilloma virus, of which 7%to 12%will develop into warts, and 2%of people are required to treat warts each year. Virus warts can be spread by themselves and can also be contagious.

Wu Yan pointed out that the treatment of past virus warts includes topical drugs, freezing, laser, local injection 5-fluoroprimidine, interferon, etc., injecting and freezing treatment. The local pain is severe. May accept treatment. And these treatments must be performed many times, and each treatment is painful. Pain causes patients to do not want to seek medical treatment. Therefore, the method of exploring good efficacy, low degree of pain, and convenient operation is a clinical problem that needs to be solved urgently.

Needle -free injection is an needle -free method of administration, that is, liquid penetrates the skin through high -current speed to complete the drug transportation; needle -free injection has the characteristics of efficient, fast, accurate, and painful pain. This method was originally developed for mass vaccination in the late 1940s. In recent years, the technology has developed rapidly in the clinical field, and has been used in local anesthesia, genes and polymer quantitative compounds, such as insulin and growth hormone transmission. There are fewer applications in the dermatology.

The team of Professor Wang Fei, director of the dermatology department of the CUHK Hospital, used a needle-free injection of 5-fluoroprine to treat virus warts for the first time internationally. The characteristics of simple and stable curative effect, the preliminary content of the study has been published in "Jama Dermatology". The study was funded by the Jiangsu Graduate Practice Practice Plan.

It is reported that "Jama Dermatology" currently affects 11.816/Q1, which is an important sub -publication of the medical authority magazine "JAMA" family. reputation. (Cheng Shouqin)

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