Academician Jia Weiping: Comprehensive regulation of blood sugar and improving blood sugar fluctuations, Jinlida helps diabetes Chinese medicine treatment towards international

"Long -term chronic hyperglycemia patients with diabetic patients can cause changes in microchaser of various organs and tissues throughout the body. In severe cases, even blindness, renal failure, amputation, and severe neuropathy are required. Therefore, HBA1C is required to control HBA1C below 7%during clinical treatment. However, in clinical observations, some patients with HBA1C <7%and the blood glucose value of an empty stomach have reached the standard. Due to the large blood sugar fluctuations and high blood sugar 2 hours after a meal, chronic complications of diabetes may still occur. "

At the main forum of the 18th International Conference, Professor Jia Weiping, an academician of the Chinese Academy of Engineering and director of the National Grass -roots Diabetes Prevention and Management Office, made a keynote report entitled "Research on the Research on Blood Sugar fluctuation abnormalities and Jinlida Intervention". Combined with the results of evidence -based medical research and guidelines, it focuses on sharing the advantages of Jinlida particles developed under the guidance of the theory of neat disease to interfere with diabetes and improve blood sugar fluctuations. In the report, she emphasized that for the long -term management of diabetic patients, clinicians must not only pay attention to the decline in the overall blood glucose level of the patient, but also the improvement of blood sugar fluctuations.

Multiple evidence -based evidence support

The only Chinese medicine that is included in the English guide in my country

"Academician Wu Yiling based on the theory of linked disease, and proposed a new point of view of thirst (diabetes) from the" spleen 'theory of treatment, and discussed the effects of spleen main transportation abnormality and pancreatic dysfunction on the incidence of type 2 diabetes and the incidence of type 2 diabetes and the incidence of type 2 diabetes. The inherent mechanism of the complications of diabetes caused by spleen loss of health and phlegm stasis and stasis. "

Academician Jia Weiping introduced that the Jinlida granules under the theoretical guidance of the neat pathology are mainly "nourishing qi and nourishing yin, strengthening the spleen and transportation". Litchi nuclear spleen, lychee, lympite, Catalmanship, spleen heat, yellow essence, Ophiopogon to nourish the spleen and yin, pueraria up to clear qi, and Danshen spleen, and finally reached "passing the veins, transportation spleen and Jinjin", making Jin Zi and Li Zida — - And this is also the source of the name of Jinlida granules.

In the report, Academician Jia Weiping systematically reviewed the evidence -based medical research evidence of Jinlida granules. A random, double -blindness, parallel control, and multi -center clinical study carried out by Academician Kobayashi, and was included in 192 cases of dose -stable dose for 3 months of blood glucose control. Da Group and Erjia Shuanglian+Placement Group. Studies have shown that after 12 weeks of medication, adding Jinlida granules on the basis of the two -meta and double pupa can further reduce 0.92%of glycated hemoglobin (HBA1C) and reduce the empty blood glucose (FPG) 1.34 mmol/L. /L, significantly improved the islet β cell function index (P <0.05), improves thirst, fatigue, constipation and other symptoms, and has high safety.

In order to further explore the advantageous people of Jinlida particle treatment, the researchers have further analyzed the study. The results showed that for patients with 8.5%and ages in HBA1C> 8.5%, age> 60 years old, the effect of reducing HBA1C and empty blood glucose, and improving insulin resistance was more significant.

Based on this research, another 15 random control clinical research (RCT) analysis (RCT) analysis (total 1810 patients) in my country was incorporated with the team carried out by Academician Kobayashi team. Lida particles can further reduce FPG, PBG, and HBA1C patients with type 2 diabetes, while improving the islet function and reducing weight.

With the strong support of evidence -based evidence, the 2017 and 2020 editions of the "China Type 2 Diabetes Prevention Guide" and the English version of "China Type 2 Diabetes Diagnosis and Treatment Standards" released in 2019, "National Grassroots Diabetes Prevention Management Guide (2022) "Multiple diabetes prevention guidelines listed Jinlida particles as recommended medications.

"This is also the only Chinese patent medicine included in the English guide in my country." Academician Jia Weiping emphasized that the release of the English version of the guide made the international fellow recognize that the prescriptions and patents represented by Jinlida granules were played in type 2 diabetes treatment. The good effect allows the Chinese medicine prevention and treatment of diabetes to the world. Significant improvement of blood sugar fluctuations

Jinlida adds new evidence to the prevention and control of diabetes

In order to observe the effects of blood glucose, glycated hemoglobin, blood glucose fluctuations, oxidation stress indicators and metabolic groups in patients with type 2 diabetes patients in patients with type 2 diabetes patients, discuss the insulin resistance of type 2 diabetes, the function of insulcal B cells, and the clinical of patients Symptom mechanisms provide theoretical basis for TCM treatment of type 2 diabetes. Academician Jia Weiping led the random, double -blindness, and control clinical study of the blood sugar fluctuations of Jinlida granules on type 2 diabetes. She introduced that the study adopted a random group, between 160 cases between 30 and 70 years old, 7%≤ HBA1C ≤ 10%, BMI ≥ 18.5kg/㎡, and type 2 diabetes patients who had not been treated. The group, the Jinlida group, the two -meta dual -tadpole group, and the two -metal dual -dual -tado+Jinlida group were followed up in 4 weeks, 8 weeks, 12 weeks, and 16 weeks of medication.

According to Academician Jia Weiping, in the study, in addition to the use of blood -sampled sugar and fat metabolism, it also applied continuous glucose monitoring technology as an important source of evaluating blood sugar changes and fluctuation data, and at the same time added the graded quantitative scoring standards of traditional Chinese medicine symptoms. "In order to prevent patients from seeing emotional fluctuations because of seeing their blood sugar changes, when evaluating blood sugar fluctuations, we adopted the subject of retrospective blood sugar monitoring of the subject in the baseline and 16 weeks. Standard deviation (SDBG), blood glucose mutation coefficient (CV), and time (TIR) ​​such as the scope of blood glucose target within 24 hours. "

The results of the research show that based on the guidance and drug treatment of the patient's lifestyle, HBA1C, FPG, PBG, and traditional Chinese medicine syndrome scores have significantly decreased from the baseline, but the Jinlida group, the two -metal dual -tadpole group, and Jinlida+two -metamical combined therapy The decline in the group is more obvious, and the scores of traditional Chinese medicine have improved. In terms of blood glucose fluctuations, compared with the control group, the blood glucose level standard deviation of the Patients of Jinlida particles decreased significantly after treatment (-0.39 vs. 0.11, P <0.01), and the time (TIR) ​​within the blood glucose target range (TIR) ​​was treated after treatment A significant improvement (23.21%vs. 2.24%, P <0.01), and the TIR of the Patients of the Jinlida particle group increased from 55%before treatment to 79%after treatment.

Academician Jia Weiping said that research tells us that Jinlida granules not only have a good curative effect in reducing the overall blood glucose level of patients, but also have a significant advantage in reducing blood sugar fluctuations. This study was also officially published in the only Chinese journal in the field of diabetes in October 2021- "Journal of Diabetes Research".

Summarize

Under the guidance of "equal emphasis on traditional Chinese and Western medicine", Chinese medicine is included in the national diabetes prevention system, and has gradually formed a new model of diabetes prevention and control in the coordinated development of modern medicine and traditional medicine in my country. The treatment of traditional Chinese medicine in diabetes follows the principle of dialectical treatment, and plays an important role in collaborative hypoglycemic, improving symptoms and signs, preventing complications, improving the quality of life, and three prevention of life.

As the representative drug of Chinese medicine in Chinese medicine in Chinese medicine, the foundation and clinical study of Jinlida particles have proved that the use of Jinlida particles on the basis of western medicine can improve the function of islet β cell function and insulin resistance, further reduce HBA1C, fasting stomach Blood glucose and postprandial blood sugar, reduce weight, and improve symptoms. At the same time, Jinlida particles can improve blood sugar fluctuations and make blood sugar control more stable. The pathogenic mechanism of Jinlida granules intervention in diabetes and its complications brings multiple benefits to patients, and provides more choices and help for clinical diabetes management.

The successful experience of Jinlida Granules, for the combination of Chinese medicine and modern science, promote the complementary and coordinated development of Chinese medicine and western medicine, promote the high -quality development and world of traditional Chinese medicine, comprehensively promote the construction of healthy China, better protect the people Health is also of great significance.

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