Singer vaccine rushed to hot search: 3207 yuan and two stitches, should I hit it?

Zhongxin Jingwei June 20th (Wang Yuling) On the 20th, "It is recommended to bring parents to inoculate shingles vaccine as soon as possible", "shingles can be lurked in the body for decades" topics.

In this regard, some netizens commented that "following HPV and Helicobacter pylori, a shingles vaccine, the 21st century vaccine anxiety." So, is it discussed whether a shingles vaccine is "vaccine anxiety"? What is the relationship between vaccine supply and demand? Who is producing?

Conditions can be vaccinated

The so-called shingles, commonly known as "raw snakes" and "waist dragon". According to Shanghai Disease Control, it is a chickenpox that has been lurking in the back of the spinal cord or in the cranial nerve festival for a long time-the schwrack virus (VZV) The infectious disease caused by activation is mainly clinically manifested in herpes that appear differently and clustered along the nerves of the surrounding side of the body.

Shock-shaped shingles and chickenpox can be described as "the same root". Yan Yan, deputy chief physician of the dermatology department of the Department of Plastic Surgery Hospital of the Chinese Academy of Medical Sciences, wrote in "There is a doctor" that shingles are not chickenpox, but these two diseases are from chickenpox-belt Caused by herpes herpes virus infection, chickenpox is caused by the initial infection, and shingles are a manifestation of the lack of virus and recurrence infection after the chickenpox cure.

Zhongxin Jingwei noticed that two significant characteristics of shingles have two significant characteristics. One is the high incidence infection rate. According to public information, shingles are more common in people with older age, immunosuppressiveness or immune defects. According to Professor Chang Jianmin, director of the dermatology department of Beijing Hospital and deputy director of the Department of Dermatology, Peking University, in my country, about 99.5%of the 50-year-old adults in the age of 50 and above are enjoys chickenpox-shingles virus, people 50 years old and over There are about 1.56 million shingles, and the "Consensus of Chinese Experts" of neuralgia diagnosis and treatment of nerve pain after zostering "pointed out that the annual incidence of shingles is about 3-5 ‰.

The second is the huge pain that patients need to bear. According to Hangzhou CDC, shingles are very painful, such as knife cutting, fire burning, electric shock, whipping, the degree of pain is higher than childbirth, and even some patients will have inattention, sleep disorders, anxiety, depression, etc. Status, double torture by physiological and psychological. Some netizens commented: "Once you get sick, invade the nerves, it hurts."

Singer vaccine, that is, reorganized shingles vaccine (CHO cells). It was officially listed in my country in early July 2020. It is suitable for preventing shingles. The vaccination object is an adult 50 or above. The vaccination interval is 2 months, and the longest is not more than 6 months. According to the Shanghai Centers for Disease Control and Prevention, shingles vaccine can provide more than 90%of the vaccine effectiveness of all 50 years and above, and the protection effect has not dropped significantly after vaccination.

Should ordinary people vaccinate shingles vaccine? The dermatologist of a three -level hospital said to the Sino -Singapore Jingwei: "Conditions are inoculated, but it is not necessary."

Hesitant because of price

What are the conditions for "condition"?

On the one hand, according to the "Consensus Experts of Zospellings Vaccine Prevention", its recommended age is 50 years old and more immune (whether the individual has a history of chickenpox infection or a chickenpox vaccine) vaccination Those who have a serious allergic reaction to any component of the vaccine. The reorganized shingles vaccine listed in my country is a drug reduction vaccine, and it is not recommended for patients with immune function defects or immunosuppressive diseases.

On the other hand, the price of vaccination is higher. Because the shingles vaccine belongs to the national immunization plan, the patient needs to pay by patients. The price announced by the Shanghai Disease Control Center is 1603.5 yuan/dose, and the full vaccination price is 3207 yuan, which is also the general price of community centers in various places.

On the platforms such as JD.com, some private hospitals can vaccinate shingles, including Human Hospital, New Century Maternal and Children's Hospital, Taihe Maternity Hospital, etc. The price is slightly higher than the community health center, ranging from 3200 yuan to 3900 yuan.

Due to price issues, the staff of the community service center in a place told Zhongxin Jingwei that many people have to wait and see if they have been vaccinated with shingles. "Last month we reported 10 seedlings with the disease control. This month was a little more, and it was not bad before. It was more expensive, but it was too expensive. . "The staff member said.

However, in recent days, due to various factors, the inoculation of shingles vaccine has increased, and even "out of stock" in some areas. According to the Health Service Station of Pazhou Street, Haizhu District, Guangzhou City, due to the large number of people with a recent zoster -shaped vaccine, the vaccine inventory is tight, and residents who have reservations must wait patiently.

The Health Service Center of Fenghuang Street Community, Tianhe District, Guangzhou stated that shingles vaccine was out of stock. It is expected to be delivered on July 19. The Jinhua Street Community Health Service Center of Liwan District, Guangzhou City stated that there is no inventory with a shingles vaccine, and it is expected to be distributed at the end of the month.

Domestic listing enters countdown

In the end, it is worth noting that there is only one reorganized shingles vaccine (CHO cell) in China to go public in my country, which is Shingrix (Xin Anli), which is a reorganized band -shaped shingles vaccine developed and produced by GlaxoSmithq.

In October 2017, Shingrix was approved by the US Food and Drug Administration to prevent herpes zoster in the age of 50. In November 2018, the reorganization of shingles vaccine (CHO cells) Essence In early July 2020, the shingrix was officially launched in China in my country for reorganization of shingles vaccine (CHO cells) and used for the prevention of herpes zoster in the age of 50 and above. According to the 2020 annual report of Watson Bio, of the top ten vaccines in the world's highest sales volume, GlaxoSmith's reorganization with shingles vaccine Shingrix ranked fifth, with sales revenue only 2.57 billion US dollars in 2020.

Zhongxin Jingwei noticed that Shingrix's US sales price is lower than China. According to the official website of Goodrx, without any insurance and coupons, Shingrix's retail price in the United States was US $ 211.15 per pin, equivalent to RMB 1,413. The discount rate of Shingrix ranges from 7%to 26%, that is, the full vaccination price is equivalent to between 2057 yuan and 2510 yuan.

Screenshot of goodrx official website

At present, many domestic pharmaceutical companies are researching and developing herpes herpes vaccines, including 100 grams of biology, Shanghai Biological Products Research Institute, Green Bamboo Biology, and Yidao Biology.

From the perspective of R & D progress, 100 grams of creatures may be topped. According to Anxin Securities, in April 2022, the application of Bio bio -reorganization with shingles vaccine was applied for NMPA acceptance. Green bamboo biore reorganization with shingles vaccine entered the second phase of the clinic, and the Shanghai Biological Products Research Institute's shingles vaccine entered the 1/2 phase of the clinical clinical, and the Yido biorer -reorganization band -shaped shingles vaccine entered the 1/2 phase of the clinic.

According to the analysis of Debon Securities, according to the US CDC data, the penetration rate of herpes zoster vaccine over the age of 60 in the United States in 2017 was as high as 34.9%. The needs of the United States in 2020 are calculated that the coverage rate of herpes zoster vaccines over 50 years of age is nearly 41%. In China, my country has not been listed in herpes zosterity vaccine shortly after the market. The growth potential of herpes vaccine market space is huge. (For more report clues, please contact Wang Yuling, the author of this article: [email protected]) (Zhongxin Jingwei APP)

(The views in the article are for reference only, do not constitute investment suggestions, have risks in investment, and need to be cautious to enter the market.)

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Editor in charge: Li Zhongyuan

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