The nine -valent HPV vaccine is enlarged. Should they fight?

Recently, the nine -valent HPV vaccine applicable population expansion has attracted attention.

On the evening of August 30, the website of the State Drug Administration showed that the indication of Merida's nine-valent papilloma virus vaccine (wine yeast) (hereinafter referred to as the nine-valent HPV vaccine) was expanded. Earlier applicable age is 16 to 26 years old.

The vaccine has not changed.

According to the official website of the State Drug Administration, on April 28, 2018, the State Drug Administration has the conditions to approve the listing of the above -mentioned nine -valent HPV vaccine, which is suitable for women aged 16 to 26. Why can the same vaccine expand from the age of 16 to 26 years to the age of 9 to 45 in how many years?

"The approval of the appropriate age of my country's vaccine requires strict research data support." Bi Yan, chief physician of the Obstetrics and Gynecology Department of Peking University First Hospital, said in an interview with the reporter of Zhongguang.com. It has not completed China's clinical research. But in 2018, the World Health Organization put forward the goal of eliminating cervical cancer worldwide, based on vaccines, and recommended 3 HPV vaccines clinical applications. At that time, the industry's voices of HPV nine -valent vaccines also also Very high. Therefore, the State Drug Administration approved its listing according to the data of the East Asian population. "

In this regard, the official website of the State Drug Administration has clearly stated that the listing of the Nine -Valental HPV vaccine is directly used in Chinese registration according to overseas clinical data. The reason why the approved population is set to a 16 to 26 -year -old woman from three aspects: from three aspects:

1. The key clinical trials that support HPV nine -valent vaccines are available for women 16 to 26 years old. Its benefits are greater than risks.

2.9 to 15 -year -old female pediatric subjects have adopted an immunogenic bridge test, and the clinical research data of the East Asian population is limited.

3. Women over 26 years old have a greater possibility of exposing HPV infection, and at the time, they did not obtain evidence that the vaccine had protected people after the exposure of the age group.

Bi Yan introduced: "Now, the HPV nine -valent vaccine has Chinese clinical research data, and found that the immunogenicity of women aged 9-15 and 27 to 45 is consistent with those 16 to 26 years old. That is to say, there are the same protection. Effect. Therefore, you can expand the applicable age to 9 ~ 45 years. "

She pointed out that vaccine is a special drug, and safety and effectiveness are its two foundations. It is precisely these two points that the above -mentioned changes will occur.

So, do the HPV vaccine be hit?

Can it be guaranteed once?

How to prevent cervical cancer?

What is HPV virus?

HPV (human papilloma virus) is a common genital tract infection virus that is mainly transmitted through sexual contact and the skin, mucous membranes or body fluids of the infected person.

According to the "2018 National Cancer Report" released by the National Cancer Center, nearly 80%of women have encountered HPV virus infections in their lives in my country, and they are mostly 20-30 years old.

There are about 100 members of the HPV virus family discovered by humans. According to different types of HPV, the danger of tumor is induced by different types of HPV, which can be divided into low -risk and high -risk HPVs.

High -risk HPVs include HPV16, 18, 31, 33, V35, 45, 51, 52, 56, 58, 61 and other types. In addition to causing genital warts, external genital cancer, cervical cancer, and height cervical epithelial internal tumor tumor tumor tumor tumor tumor tumor tumor tumor tumor tumor tumors The occurrence of changes is high.

Low -risk HPV can cause skin and even external genital warts.

Fortunately, cervical cancer is the only cancer that can be prevented by vaccination so far.

What are the HPV vaccines? What is the difference?

At present, there are three types of HPV vaccines that have been listed in China. According to the number of subtypes of HPV viruses that can be prevented, it can be divided into two -valent, quadruple and nine -valent HPV vaccine.

Among them, the higher the "price", the more subtypes of HPV virus that can be prevented.

Dual price HPV vaccine

Prevention type: mainly for the prevention of two types of HPV viruses, HPV16 and 18 types of HPV virus. In my country, about 80%of cervical cancer is caused by HPV16 and 18.

Recommended age group: 9 ~ 45 years old.

Severaous interval: each vaccination at 0/1/June.

Quartet HPV vaccine

Prevention type: two types of HPV6 and 11 are added on the basis of binary vaccine. These two virus subtypes can cause 90%of anal and genital warts.

Recommended age group: The main population of vaccination is women aged 20-45.

Severaous interval: each vaccination at 0/2/June.

Nine -valent HPV vaccine

Prevention type: Nine -valent HPV vaccine can prevent 6, 11, 16, 18, 31, 33, 45, 52, 58 nine high -risk HPV virus infection induced cervical lesions, which can prevent more than 90%of cervical cancer. Essence

Recommended age group: vaccination object is a 9 ~ 45 -year -old woman (latest adjustment).

Severaous interval: each vaccination at 0/2/June.

The previous three HPV vaccines were all imported, and the specific price may be different in different regions.

Shout more: Don't worry first ...

After the news of the "Nine Varling HPV Vaccine Expansion" was issued, multiple media and medical institutions stated that they would have to wait ... Zhejiang:

Tianmu reporters inquired about "Zheli Office" and found that most of the recent appointment activities have stated that women only 16-26 years old can participate. The staff of the Zhejiang Provincial Center for Disease Control and Prevention said:

When the 9-45-year-old woman can take vaccination, it depends on when the clinic can get the vaccine after the instructions. Therefore, the newly approved age group can still wait for a period of time.

Shanghai:

Surging news reporters interviewed a number of community health service centers, and the other party said: "I have not received a notice from women 9-45 years old.

At present, whether it is imported four-price or nine-valent HPV vaccination, you need to make an appointment in advance. The shortest waiting time takes a few months, and it takes 1-2 years.

The obstetrics and gynecology hospital affiliated to Fudan University also stated in the WeChat public account that our hospital has not received a notice of nine -valent vaccine expansion.

Henan:

According to elephant news reports, a staff member of a community health center in Erqi District of Zhengzhou City introduced that due to the news of the expansion of the applicable population of the nine -valent HPV vaccine, they have not received relevant notices from the superior department.

At present, citizens other than 16-26 can not be vaccinated. It is expected that a number of nine-valent vaccines under Merida East will arrive in Zhengzhou in September. Everyone can make appointments in advance.

Doctor said

Not recommended to blindly pursue vaccination nine -valent HPV vaccine

It is also recommended to take vaccines in time when you are age

Inoculation two -price and quadrimal HPV vaccine

It can also play a good prevention effect

It is not recommended to increase the scope of protection

Waiting for a higher price vaccine

And miss the best prevention timing

HPV vaccine cannot replace cervical cancer screening

HPV vaccine can only reduce the probability of cancer

It cannot prevent all high -risk HPV types

Therefore, even if the vaccine is vaccinated

Cervical cancer screening is also required

Source: Xiaokang Headline Comprehensive CCTV, China News Network, Tianmu News, Surging News, China Youth Daily, Science Popular Science China

Responsible editor: Tian Yuan Yingying

School pair: Wu Jinyang

Review: Gong Zimo

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