Why is the HPV nine -valent vaccine expanding?Should I fight?Experts say that

Author:Zhejiang Daily Time:2022.09.01

Zhejiang News Client reporter Zheng Wen

On August 30, the new indications of the Nine -valent HPV vaccine were approved by the State Drug Administration. The applicable population expanded from the age of 16 to 26 to 9 to 45 years old.

Cervical cancer is currently the only cancer that can be prevented by vaccine. The sooner the age of women, the better. The Meridas' HPV vaccine was approved to be listed in China in 2018. At that time, their applicable age groups were women aged 16 to 26. Many women willing to vaccinate were rejected because of "oversized" reasons.

Why is the age of nine -valent HPV vaccine relaxing? For more problems about HPV vaccines, the reporter interviewed Shou Huafeng, deputy director of the Gynecology Department of Zhejiang Provincial People's Hospital, and Ma Yuanying, deputy director of the Women's Health Department of the Obstetrics and Gynecology Hospital of Zhejiang University Medical College.

1. Why is the nine -valent HPV vaccine expanding age?

Ma Yuanying: Most of the HPV vaccines abroad are suitable for 9-45 years of age. The approval of China's HPV nine-valent vaccine aging is fully verified by clinical research and confirmed that the protection effects and safety of women aged 9-15 and 27-45 years old Only then was approved.

2. Is it necessary to play nine -priced after playing two prices and four prices?

Ma Yuanying: This problem is also particularly concerned by everyone. There are relevant clinical trial verification in foreign countries. After the vaccination of 3 doses and four -valent vaccine, the nine -valent vaccine is safe and effective after 12 months. Research evidence. It is not recommended to change the price of the two -price or four -price price, and lack of relevant security and effective research evidence.

From the perspective of preventing cervical cancer, the second and fourth valence can prevent about 70%of cervical cancer, and the nine valence can prevent about 90%of cervical cancer. Under the current HPV vaccine, according to the first-level prevention strategy of cervical cancer, it is not recommended to complete the second or fourth prices and then go to the nine-price price. You should give priority to women who are 9-15 years old. The crowd can achieve better group effects to prevent cervical cancer.

3. Is it necessary to vaccinate the HPV virus that has been infected with HPV virus?

Ma Yuanying: The probability of the infection after HPV infection is existed, and the antibodies produced by the natural infection through HPV are difficult to prevent the same type of HPV infection again. However Vaccination is also effective for preventing re -cable infections.

4. Is there a protection period for vaccine? Is it necessary to perform cervical cancer screening after vaccination?

Ma Yuanying: Since the listing of HPV vaccines in 2006, long -term follow -up studies have confirmed the effectiveness of the HPV vaccine for 14 years, but there is no evidence to confirm that the HPV vaccine has a lifelong protection effect.

HPV vaccines do not prevent all HR-HPV types. A few cervical cancer may have nothing to do with HPV infection, especially HPV-negative special types of cancer, so it cannot achieve 100%protection effect. After inoculation of HPV vaccine, women with sexual life still need to screen cervical cancer every 3 to 5 years. HPV and cervical cytology are recommended.

5. Is HPV's harm really great?

Shouhua Feng: The cause of cervical cancer is very clear, which is related to 99%HPV infection. 80 % of women may have infected HPV viruses in their lives. HPV infection is divided into two forms: most of the "one excessive HPV carrying status" and a small number of "persistent infections". However, only high -risk types of persistent infections are closely related to the occurrence of cervical cancer.

6. What should I do if I can't get the vaccine in the age? Can vaccines replace cervical cancer screening?

Shouhua Feng: Inoculation of HPV vaccine does not replace cervical cancer screening. Combining vaccination and cervical cancer screening is the best means to prevent cervical cancer. If not vaccinated on time, regular screening should be screened. The vaccine is first -level prevention. The second -level prevention is early discovery and early treatment.

Cervical cancer itself is good after it is found. If it is found early, the cure rate is above 95%. The younger can still retain fertility and ovarian function. There are many ways to treat modern medicine, so don't mention HPV infection and feel very panic.

7. Can I get HPV vaccines during pregnancy, pregnancy, and lactation?

Shouhua Feng: No suggestion. We recommend that before marriage, HPV screening and cervical thin -layer cytology examination (TCT), there is a problem in advance. If you are pregnant, you will be passive if you find that there are cervical lesions.

【Zhejiang News+】

Visual China Map

The "price" of the HPV vaccine does not refer to the price, but the virus type that can prevent the vaccine. Several vaccines that can prevent several types of vaccines are called price vaccines. Human nipple virus (HPV) is a "big family", including more than 200 different types. According to their characteristics, they are divided into two categories: low -risk types such as type 6 and 11, which are mainly related to genital warts; high -risk types such as 16 and 18 types, mainly related to cervical cancer.

Among the HPV vaccine, the type 16 and 18 types can be prevented called two -valent vaccine. In addition to the 16 and 18 types, the quasal vaccine can also prevent type 6 and 11. Type 6, 11, 16, 18, 31, type 33, type 45, 52, 58.

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