Chinese Medicine Enter the main position of diabetes prevention and control | International List Disease Conference • Diabetes Forum

Physician News (Rong Media Reporter Huang Jing) "Traditional Chinese and Western Medicine is an important strategy and policy for my country's prevention and treatment of diabetes. In the" Guidelines for the Prevention and Treatment of Diabetes (2022) "released this year, the Chinese medicine prevention chapter of diabetes was added for the first time. "

Recently, at the 18th International List Diseases Conference and the Ninth Chinese and Western Medicine Integrated Vascular Diseases Forum held in Guangzhou, the chairman of the forum, the chairman of the Director of the Endocrinology Professional Committee of the Chinese Medical Association, and Zhao Jiajun, Dean of Shandong Provincial Hospital The professor has once again emphasized that in recent years, Chinese medicine has obtained more and more evidence of evidence -based medical evidence, and gradually entered the main position of diabetes prevention and control, playing an important role.

Professor Zhao Jiajun

Academic speech

Academician Ning Guang

"As the Three Hospital, Ruijin Hospital affiliated to Shanghai Jiaotong University has always adhered to the principle of common development of traditional Chinese and western medicine, and established an excellent tradition of combining traditional Chinese and western medicine for the treatment of diseases." Experts of endocrinology metabolic disease and Academician Ning Guang of the Chinese Academy of Engineering pointed out at the conference speech. Pathological theory is a model of inheritance and innovation of traditional Chinese medicine. It systematically constructs the treatment of linked diseases, the doctrine of the vein, and the theory of gas, and has guiding value for the prevention and treatment of a variety of refractory diseases. In the prevention and control of diabetes and other diseases, the theoretical guidance of the theory of the neat disease has shown more and more development prospects and exact effects.

Academician Xiaolin

"The series of innovative drugs developed under its guidance and its guidance, played a major role in major clinical diseases such as cardiovascular and cerebrovascular, endocrine, immunity, urology and other major clinical diseases and sudden respiratory public health events, and achieved breakthrough results. It has made important contributions to the development of Chinese medicine in my country, and has significantly enhanced the international influence of Chinese medicine. "Scientists and academicians of Chinese Academy of Sciences and Chinese Academy of Sciences said that the study of traditional Chinese medicine in accordance with the law +Clinical+New Medicine+Experimental+Evidence -based Integrated Chinese Medicine Academic Innovation and Transformation and Development Model. It has taken a successful road to success in traditional Chinese medicine and multi -disciplinary cross -development. demonstration.

Diabetes Forum venue

As one of the core sub -forums of the International Conference of the International List Diseases, Diabetes Forum has extensive exchanges on the theoretical guidance of diabetes theory and the research progress of Tongluo Pharmaceuticals.

Professor Guo Lixin, the National Elderly Medical Center of Beijing Hospital, Professor Li Xiaoying, Zhongshan Hospital affiliated to Fudan University, Professor Xiao Xinhua, Beijing Union Hospital, and Professor Yan Li of Sun Yixian Memorial Hospital of Sun Yat -sen University as an academic link. It shared and in -depth analysis of the current status of diabetes diagnosis and treatment, the new version of the diabetes prevention guidelines, and the diabetes diagnosis and treatment guidance of the theory of linked disease theory, and deepened the participants' understanding and understanding of diabetes diagnosis and treatment under the guidance of Chinese medicine treatment of diabetes, especially under the guidance of the theory of linked disease.

Diabetes therapy for the theory of linked disease

Highlight the "tone" intervention strategy

Professor Park Chunli

"Diabetes and its complications, Chinese medicine calls it thirst, belongs to the category of traditional Chinese medicine. Ye Tianshi of the Qing Dynasty proposed the argument of 'chronic disease in the collateral' '' ''. The healing type of diseases are classified as linked diseases, including chest palsy, stroke, thirst, etc. ". Professor Park Chunli Park Chunli, deputy chairman of the Diabetes Branch of the Chinese Medicine Society and Professor Park Chunli, Shenzhen Hospital of Guangzhou University of Traditional Chinese Medicine, emphasized in the report that the treatment of this type of disease was not effective in the treatment of traditional scientific prescriptions. The amplitude increases the ending of the treatment of diabetes and complications.

The theory of linked disease highlights the "tone" intervention strategy, which believes that "tuning" is different from confrontation and alternative therapy, including the treatment of camps, qi and blood, yin and yang, qi and gasification of the five internal organs, qi gasification, evil and reality, and the internal and external environment is harmonious and balanced Wait.

Guided by the theory of linked disease, the Chinese medicine Jinlida granules made from the spleen theory, have the effects of protecting the islet β cells, reducing insulin resistance, and regulating sugar fat metabolism. Essence

"Jinyu Plan"

It is a model for China and the West to treat diabetes

Traditional Chinese medicine has been widely used in the full cycle of diabetes prevention and control during the whole process. In the future, it should establish a clinical diagnosis and treatment system for complementary Chinese and Western medicine under the diabetic prevention and control system led by modern western medicine to highlight the characteristics of traditional Chinese medicine in diabetes prevention and control. Essence

Professor Lian Fengmei

According to Professor Lian Fengmei of Guang'anmen Hospital of the Chinese Academy of Traditional Chinese Medicine, a clinical study led by Academician Kobayashi was included in a total of 192 cases of two -month -old dose -stable dose for 3 months of blood glucose and still poor control.研究结果显示，在二甲双胍基础上加用津力达颗粒可进一步降低糖化血红蛋白（HbA1c）0.92%，显著提高胰岛β细胞功能指数、降低患者空腹血糖和餐后2小时血糖，改善口渴、乏力、 Symptoms such as constipation.

Professor Lian Fengmei emphasized that Jinlida is a model for Chinese medicine to treat diabetes. It has both reliable clinical effects and support for evidence -based medical evidence, so that doctors can use it with confidence.

Brown fat may become

New targets for treatment of obesity and diabetes

The 2017 and 2020 "Guidelines for Prevention and Treatment of Diabetes in China" released by the Chinese Medical Association Diabetes Branch added diabetic Chinese medicine treatment chapters. The guide emphasizes that the application of traditional Chinese medicine follows the principle of dialectical treatment, and plays an important role in synergistic reduction in symphalasia, improve symptoms and signs, prevent complications, improve the quality of life and three levels of prevention. The guide proposes that for type 2 diabetic qi and yin and two deficiency syndrome, on the basis of the application of hypoglycemic drugs such as di metarium, you can take Tianlida granules. Professor Chen Li, deputy chairman of the Chinese Medical Association Diabetes Branch and Professor Chen Li of Qilu Hospital of Shandong University, brown fat can promote glucose intake and improve sugar metabolism; promote triglyceride to remove triglyceride and improve blood lipids; increase energy consumption and reduce weight. At present, many clinical and basic studies have confirmed that increasing brown fat production has a variety of beneficial effects such as obesity that inhibit high -fat diet induced, improves sugar -lipid metabolic disorders, and insulin resistance. Therefore, activating brown fat function may become a new strategy of obesity and type 2 diabetes.

Professor Chen Li

A series of basic research shows that Jinlida particles can activate brown fat cells, increase mitochondrial content and respiratory function in the cell, and then increase the activity of brown adipose tissue. Professor Chen Li pointed out that Jinlida particles activated the brown fat heat production function is one of the mechanisms for its role of hypoglycemic. This is used for type 2 diabetes for Jinlida granules. Experimental basis.

Blood disorders and insulin resistance affect each other

The diabetic pathogenic mechanism is complicated, and the increase in blood glucose is only the corner of the iceberg. Its potential factors include insulin resistance, oxidation stress, abnormal blood lipids, and hypertension. Professor Song Guangyao, director of the Hebei Provincial Institute of Endocrine Metabolism and the Department of Endocrine Department of Hebei Provincial People's Hospital, pointed out that blood lipid disorders and insulin resistance affect each other, which is the central link of diabetes and vascular lesions.

Insulin resistance is an important pathological mechanism for diabetes, but there are fewer western medicines that are currently improving insulin resistance. Professor Song Guangyao pointed out that the traditional Chinese medicine pathogenesis of insulin resistance is mainly related to spleen loss, liver qi stagnation, and lack of kidney qi. In the treatment Starting from dehumidification, there are many single -medicine or compound patent medicines that are effective in insulin resistance.

Professor Song Guangyao

Professor Song Guangyao introduced that Jinlida particles under the guidance of the theory of the neat disease can interfere with diabetes from multiple targets such as improving insulin sensitivity, antioxidant factors activity, reducing inflammatory factors, and inhibitory hyperglycemia secretion. The basic research and clinical case control research of Jinlida particles confirmed that it can improve the diabetic insulin resistance by regulating the metabolism of sugar fat, thereby more effectively controlling blood sugar.

Improve blood sugar fluctuation is a new idea of ​​diabetes treatment

Professor Pan Jiemin of the Department of Endocrine of the Sixth People's Hospital of Shanghai said that blood sugar fluctuations are closely related to the occurrence and development of chronic complications of diabetes. In terms of complications of large blood vessels, blood glucose fluctuations are significantly related to the severity of the patient's coronary heart disease, and their role is independent of the blood glucose level itself. In terms of microvascular complications, blood sugar fluctuations are related to the excretion of microcin protein and diabetic retinopathy. Therefore, while the blood glucose management improves the glycated hemoglobin and prevent hypoglycemia, it is also necessary to improve blood sugar fluctuations and three prongs.

Professor Pan Jiemin

"Time (TIR) ​​within the range of glucose is a new indicator of blood sugar fluctuations. It is increasingly watched. Many guidelines have incorporated it into the target of blood glucose control and become an important blood glucose monitoring indicator." Professor Pan Jiemin introduced that it was transported by Shanghai Traffic. Academician Jia Weiping, a university affiliated to the Sixth People's Hospital, has the clinical research on the influence of blood glucose fluctuations in patients with type 2 diabetic patients. The results show that Jinlida particles can significantly improve patients with sugar metabolism (glycosylly glycosin, empty blood glucose, postprandial blood sugar). And Chinese medicine syndrome score. Compared with the control group, the blood glucose level standard deviation of the Patients of the Jinlida particle group decreased significantly after treatment (-0.39VS. 0.11, P <0.01), and the TIR of the Patients of the Jinlida granules increased from 55%before treatment. 79%after treatment. It shows that Jinlida particles can improve the blood glucose control and blood sugar fluctuations of patients with type 2 diabetes.

Purpose of hypoglycemic

To reduce diabetes complications

A 70 -year -old female patient has a history of diabetes for 3 years, a history of coronary heart disease and hypertension for 10 years. In November 2021, local hospitals suggested that patients were treated with insulin. After that, the patient had hypoglycemia and other hypoglycemia symptoms, 2 to 3 times a day. In January 2022, chest tightness, breath, pain, pain in the first zone of the heart, diagnosed acute lower wall myocardial infarction, at that time, the blood glucose was 2.8 mmol/L.

"Patients appeared in the treatment of large vascular complications when I went to me, and I felt very heartache." Professor Xu Chun, the Third Medical Center of the General Hospital of the PLA, emphasized that the problem of hypoglycemic hypoglycemic blood sugar must be paid attention to. The purpose is to reduce the complications of diabetes.

In response to the occurrence of chronic complications of diabetes, Professor Xu Chun pointed out that excess nutrition will inhibit the AMPK signaling pathway, block and decompose metabolism, while activating the MTORC1 signaling pathway to promote synthetic metabolism. Excessive synthesis of metabolism can cause obesity, diabetes, cardiovascular and cerebrovascular diseases, and tumors.

The AMPK pathway is activated to inhibit the MTORC1 signaling pathway, improve the imbalance of energy metabolism, and bring cardiovascular benefits to patients. Professor Xu Chun pointed out that in recent years, research has found that Jinlida particles have inhibited the PI3K-AKT-MTOR channel through the sites that act on the upstream of PI3K, thereby reducing the occurrence of diabetes complications. Professor Xu Chun

Professor Xu Chun introduced that some domestic clinical studies have also confirmed that Jinlida particles can reduce the thickness of urine micro protein and neck endometriosis, improve the speed of motor nerve conduction and sensory nerve conduction speed, improve the type 2 diabetes non -proliferative retinopathy lesion changes It has a good effect on complications such as diabetic microvascular lesions and cardiovascular and cerebrovascular diseases.

"Jinlida particles have certain evidence -based medical evidence in the prevention and control of microvascular complications of diabetes, but lack of large samples and multi -center clinical research evidence." Professor Xu Chun said that he is very fortunate that recently the Chinese Medical Association's endocrinology branch, the endocrinology branch, the Chinese Medical Association's endocrine branch, The Chinese Medical Association Magazine and the Editorial Committee of the China Diabetes Magazine jointly launched the "Diabetes Prevention and Treatment of Microvascular Complication Real World Project". The project will help improve the real world clinical evidence of the complication of microchaser for patients with blood glucose and delaying type 2 diabetes, and will further promote its application and promotion in the field of diabetes and benefit more diabetic patients.

Lifetime intervention+Jinlida,

Reversing the pre -diabetes

Professor Zhao Nengjiang

A 42 -year -old diabetic patient, diagnosed for half a year, and checked 6.5 mmol/L when he came to the hospital when he came to the hospital. The blood sugar was 10.3 mmol/L in 2 hours after a meal. HBA1C6.4%. Essence At the same time as healthy mission, diet and exercise guidance, take Jinlida granules. After 1 month, the patient's empty blood glucose returned to 5 ~ 6 mmol/L, 6 ~ 7 mmol/L after a meal, and the symptoms of dry mouth disappeared, and the emotions returned to normal.

Professor Zhao Nengjiang, the First Affiliated Hospital of Xiamen University, used the real cases of his clinical work to illustrate the comprehensive management of early patients with diabetes plus Chinese medicine treatment and reverse the experience of diabetes.

In the newly released "Guidelines for the Prevention and Control Management of Grassroots Diabetes (2022)", the "Chinese Medicine Prevention and Treatment of Diabetes" chapter is newly added, and actively support and encourage Chinese medicine to integrate into the comprehensive prevention and treatment system of diabetes, give full play to the advantages of overall views, syndrome differentiation, and combine physical identification Wait, comprehensive use of drugs and non -drugs and other methods to carry out comprehensive prevention and control. The guide clearly states that in terms of collaborative sugar control and improvement of symptoms, patients with type 2 diabetes can be used on the basis of conventional treatment.

Summarize

In recent years, the prevention and treatment of diabetes in traditional Chinese medicine has achieved remarkable results, and has achieved achievements in various fields such as replacement, supplementation, efficiency, and drug reduction. As a model of TCM granules, as a model for traditional Chinese medicine to treat diabetes, it has a good performance in terms of sugar regulating liposuction and liposuction, protecting islet β cells, improving insulin resistance, improving blood sugar fluctuations, and transforming white fat into brown fat.

As a diabetic treatment drug, Jinlida particles have a multi -target attack. While reducing blood sugar, it has a good effect on the protection of large blood vessels and microvascular, which can improve the prognosis of patients.

Traditional Chinese medicine is listed as a chapter by multiple diabetes guidelines. It is an recognition of the treatment of diabetes for traditional Chinese medicine. It is also an inevitable result of the increasingly detailed evidence of evidence. The field of traditional Chinese medicine to enter the mainstream prevention and control of diabetes is a reflection of comprehensive strength.

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