Nine-valent HPV vaccine expands to 9-45 years old!Who needs to be vaccinated most?

It is difficult to find, the age card is dead, and the qualified boyfriend must take his girlfriend to do ... I am afraid that no vaccine is as hot as HPV vaccine.

No, the HPV vaccine searched again!

The reason is that on August 30, the nine-valent HPV vaccine's new indications were approved by the State Drug Administration. The applicable population was expanded to a 9-45-year-old woman inoculation. The applicable age was 16-26 years old.

At present, the nine -valent HPV vaccine that has been approved in China is the imported Meridon vaccine brand "Jiada Xiu 9". All 45 years old.

As soon as this news came out, many sisters shouted: Great! No longer need to be anxious for 26 years old!

Some netizens issued a soul three consecutive questions: The higher the price of the HPV vaccine, the better? When is the "golden age" of HPV vaccine? Can you once and for all? People who are most concerned about HPV vaccine related issues, NetEase Health "Health Follow" reveals your secrets for you!

Why do women get HPV vaccines?

HPV (Human Papilloma Virus) is called human papilloma virus, which is a general term for a set of DNA virus infected with skin or mucosa. HPV is a large family. It has been found that more than 200 types have been found. About 40 types are related to reproductive tract infections. Some types of HPV infections in some types have potential carcinogenicity.

According to HPV's biological characteristics and carcinogenic potential, it can be divided into low -risk and high -risk types.

Low -risk HPVs such as 6, 11, 42, 43, 44, etc., can cause benign changes in skin and genital warts. Common ones are common warts, plantar warts, flat warts, and genital warts. Around the anus. Among them, HPV6 and HPV11 infection are related to most genital warts and almost all recurrent respiratory nipples.

High -risk HPVs such as 16, 18, 31, 33, 35, 39, 45, 51, 56, 58, 59, 66, 68, etc. are related to cervical cancer and cervical epithelial tumor. The high -risk HPV persistent infection of the cervix may cause cervical cancer. About 90%of cervical cancer is related to high -risk HPV infection, of which 70%of the infiltrated cervical cancer is related to HPV16/18 infection.

Data show that more than 70%of women in their lives will be infected at least once HPV. HPV infections can usually be seen in 2 months after women's initial life, and about 60%of women were found HPV infections in the following 5 years.

Of course, HPV infection does not mean cervical cancer. At the beginning, most women's infection HPV was an excessive infection of no symptoms, and it may be manifested in clinically as low -grade scale epithelial lesions in the cervix. In the case of good immunity, the possibility of the virus being cleared by the body's auto immunity is higher than 80%. However, if continuous infection is continuous, it will progress into high -level scaled epithelial internal lesions. If infection is continuous, after 8-12 years, it will evolve into cervical cancer.

How terrible is cervical cancer? Its incidence and mortality ranks fourth in global female cancer, second only to lung cancer, breast cancer and colorectal cancer. About 570,000 people in the world are diagnosed with cervical cancer each year, and every 2 minutes, one woman is died. There are more than 100,000 new cervical cancer cases every year in my country, accounting for about one -sixth of the global incidence.

99%of people suffering from cervical cancer have HPV infection. Conversely, without HPV infection, women can hardly suffer from cervical cancer. Therefore, it is necessary to vaccinate the HPV vaccine to prevent cervical cancer.

When is the "golden age" of HPV vaccine?

The removal rate of HPV is closely related to age and virus existence. Studies have shown that every time after the first life increases, the HPV infection is reduced by 15%. Therefore, theoretically, the younger the age of HPV vaccine, the better. But in fact, for children in children, because they generally involve sexual behavior, there is no need to vaccinate. So, what age vaccination is best?

The World Health Organization recommends girls aged 9-14 to the preferred group of HPV vaccines. Before sexual life, the chance of HPV infection was almost zero. The HPV vaccine is used to prevent the treatment of HPV infection. It is best to complete all the inoculation of all preparations before starting sex.

The higher the "price" of the HPV vaccine, the better?

At present, the domestic HPV vaccine is divided into three types: two -valent, four -valent, and nine valence. "Valentine" represents the number of viruses that can be prevented by vaccine. The binary vaccine is aimed at HPV16 and 18 viruses. The quadrimal vaccine is aimed at the four viruses of HPV16, 18, 6, and 11. , 18, 6, 11, 31, 33, 45, 52, 58 and other 9 viruses.

This question cannot be generalized. In terms of the type of virus prevention of HPV vaccine alone, the higher the price of the HPV vaccine, the more virus subtypes it prevention. However, the prevention of the virus in the vaccine, in addition to the type of prevention of the virus, also has factors such as the cost of vaccine (that is, prevention ability) and antibody titration.

For the prevention and control of cervical cancer, in theory, the effect of two -price and four -valent vaccine is equivalent, with a protection rate of 70%, and the protection rate of nine -valent vaccines is as high as 90%. The important thing is not the cost of the vaccine, but in time to obtain the ability to protect. Earlier, China had corresponding age requirements for inoculation of different types of HPV vaccines. But at present, all types of HPV vaccines are 9-45 years old.

For female friends, according to age, economic status and local vaccine types, choose to vaccinate HPV vaccines at different valences. It is emphasized that if the vaccination time exceeds the prescribed age range, the vaccination mechanism will not be vaccinated, so the vaccination must be taken within the scope of the specified age (calculated at the age of age).

Like other vaccines, HPV vaccines are mainly carried out in community hospitals or community health service centers. They can also choose to qualified private medical institutions. You can inquire or call on online inquiry or calling for online inquiries or calling.

Is there any side effects of HPV vaccine? Can you once and for all?

HPV vaccines are specially treated with special activation, so it is safe and effective, but there will be some side reactions like all vaccine injection.

Some people may have dizziness and discomfort when they just injected, so it is generally recommended to take a break for about half an hour after injection. If there is no obvious discomfort, you can leave. The injection site may have small redness and hardships, which are generally mild. Some people may also have similar symptoms such as low fever, general soreness, etc., and they can generally relieve themselves.

In addition, HPV vaccination is by no means free of death and cannot provide 100%protection. Because the prevention and control system of cervical cancer is divided into three levels, the diagnosis and treatment of cervical cancer belongs to the third -level prevention and control. The screening of cervical cancer and the treatment of pre -cancer lesions belong to the secondary prevention and control, and the HPV vaccine is the first -level prevention and control. It can't seem to be good because the first line of defense seems to be good, so the second line of defense is withdrawn. Therefore, even if the vaccine is vaccinated, it is necessary to take regular screening according to the regular screening strategy.

This article guides experts: Tan Xianjie, PhD, professor, doctoral supervisor, chief physician of the obstetrics and gynecology department of Beijing Union Hospital. He has been engaged in the diagnosis and treatment of gynecological malignant tumors for a long time, and also deputy chairman of the Youth Committee of the Gynecology and Decision Branch of the Chinese Medical Association.

Reference materials:

1.Bray F, Ferlay J, soerjomataram I, et al. Global Cancer Statistics 2018: Globocan Estimates of Incision and Mortality Worldwide for 36 Cancers in 185 Countries [J]. CA CANCER J CLIN, 2018 (68): 394-424.

2. Smith JS, Lindsay L, HOOTS B, et al. Human Papillomavirus Type Dis-Tribution in Invasive Cervical Cancer and High-Grade Cervical LE-SIONS: A Meta-Analysis Update [J]. Int cancer, 2007 (121): 621-632.

3. De Vincenzo R, Conte C, Ricci C, et al. Long -Term Effical and Safety of Human Papillomavirus VacCination [J]. Int J Womens Health, 2014 (6): 999-1010.

4.ma B, Maraj B, Trans NP, ET Al. Emerning Human Papillomavirus Vaccines ［J]. Expert Opin Emerg Drugs, 2012 (17): 469-492.

- END -