Cold cold, will it harden?This disease cannot be maintained alone!

Sister Zhang has a trouble, that is, the fingers have always been cold and cold for the past two years. In the past two years, she is particularly obvious. After the fingers are cold, they will even become white and purple. Not only that, Sister Zhang found that her fingers and the skin on her face became tight and tight. Thinking about it, Sister Zhang decided to go to the hospital to see.

When I came to the hospital, Sister Zhang went to the rheumatism in the advice of the doctor. The doctor looked at Sister Zhang's hand and squeezed the skin on her face. After careful examination, she judged that Sister Zhang got "hard skin disease"!

scleroderma

A systematic autoimmune disease with skin thickening and hardening as prominent manifestations, characterized by microvascular injury, immune disorders and fibrosis of the skin, joints and internal organs.

"I thought it was just a problem with the skin, or it was cold and cold, and it was just under conditioning. I didn't expect it to be immune!" Sister Zhang was nervous.

Cold finger

Tighten the skin

In real life

Many people have encountered such a situation

How to judge yourself

Is it hard skin disease?

If you have hard skin disease

What should I do?

Can cause damage and disability

It may even affect life

Hard skin diseases include two types of stabbing hard skin disease and systemic sclerosis. The former only has skin changes, while the latter not only suffers from skin affected, but also often causes visceral involvement. Therefore, systemic sclerosis is the focus of clinical attention.

A large part of the patients with systemic sclerosis will gradually occur and disability, and even affect life due to severe internal organs.

Except for changes in the skin

Pay attention to the changes in the internal organs

What are the symptoms of hard skin disease? You must pay special attention to these aspects.

● Skin suffering:

Early patients may only have skin edema and tightness at the distal end of the fingers. Over time, the skin gradually shrinks and thinner. The patient gradually appears because the skin is limited and the mask -like characteristics.

● Renault disease:

In addition to changes in the skin, patients with hard skin disease often accompany fingers, toes are afraid of cold, and turn white and purple after cold. We call it "Renault disease". gangrene.

★ Finger skin thickened and accompanied by flexion contracture

★ Finger vascular spasm causes purple magpie color to change color

★ The surface of the blood vessels is expanded, commonly on the face and palms

★ Nail f "Flowing capillaries abnormal

★ Finger ulcers

● Internal organs:

Patients with systemic sclerosis often cause visceral involvement, such as pulmonary hypertension, pulmonary fibrosis, digestive tract lesions, kidney affected, kidney crisis, and so on.

The severity of these internal organs vary from person to person, and often performs very hidden in the early days. Therefore, patients need to regularly go to the specialist at the specialist to monitor and check, and strive to discover as soon as possible.

If you have an internal organs, you don't need to be too nervous. As long as early and standardized treatment, most of the condition can be stable.

Women are good, male condition may be heavier

Internal and external causes or cause or cause

The peak peak of hard skin disease is 45 ~ 65 years old. Women are good, but male patients often have a serious condition. The cause of hard skin disease is very complicated, and the cause is still being explored. Most studies believe that the occurrence of hard skin disease is the common effect of internal causes and external causes.

Some patients themselves have certain susceptible genes. Driven by the environment, such as long -term contact with silicon dust, chemicals, radiation substances, or a certain virus or bacteria, the body has a disorder of immune, which produces itself for itself. Immune attacks, various immune -related cytokines are activated, and various organs such as skin and blood vessels have gradually occurred.

Drug treatment is more complicated

Need to follow individualization to choose

The treatment of hard skin diseases is more complicated and requires individualization to choose. Commonly used drugs include glucocorticoids and various immunosuppressive agents, as well as some new methods such as biological preparations.

In addition, anti -fibrosis drugs such as Nididib and Pepidonone have also achieved good results in patients with hard skin diseases with pulmonary fibrosis.

Less contact with cigarettes, pesticides

Pay attention to life and hygiene

● Avoid contact with some substances that may aggravate the condition: for example, cigarettes can aggravate the lesions of the blood vessels. Therefore, patients with hard skin disease need to quit smoking and try not to contact second -hand cigarettes. There are also some chemicals, such as the spraying of some pesticides. After contacting the skin or inhaling the lungs, it may also increase the risk of fibrosis, and it also needs to be avoided as much as possible.

● Regular and healthy lifestyle: Long -term mental stress, staying up late, and irregular lifestyle may increase immune disorders and increase the condition.

● Diet requires healthy and easy to digest: a large part of patients with hard skin disease have digestive tract, manifested as acid, flatulence, constipation, or diarrhea. Therefore, it is necessary to choose foods that are easy to digest to reduce greasy, sweet, irritating diet. It helps to help digestive tract absorb nutrients.

● Pay attention to hygiene: Infection may be the incentives of the incidence of hard skin disease or worsening. Pay attention to personal hygiene and reduce the risk of infection.

● Pay attention to keeping warm: Warm keeping can reduce the blood vessel spasm of patients with hard skin disease, reduce the phenomenon of Renault. It is recommended to wear more gloves and try not to touch cold things with your hands.

It is not uncommon for hard skin disease. As long as early diagnosis and active and regular treatment, most patients can control the disease well. Remember, the skin is tight and hard -hard, or the fingers become white and purple, and you must go to the science department as soon as possible to let the specialist judge and treat. Finally, I wish Sister Zhang and the majority of patients with hard skin diseases soon recover!

Rheumatology and Immunology Department of Zhejiang University Second Hospital

The Rheumatology and Immunology Department of the Second Hospital of Zhejiang University was officially established in November 2002. It has a well -quality and aggressive academic echelon. It has been committed to the early, standardized, and joint treatment of the disease.Flames, ankylosing spondylitis, dry syndrome, multi -dermatitis/dermatitis, systemic sclerosis (hard cortex), systemic vasculitis, gout, osteoarthritis, osteoporosis, leukotic disease, etc.The diagnosis and treatment of ten rheumatism has accumulated rich clinical experience.The department took the lead in carrying out the joint diagnosis and treatment of difficult diseases in the province, and successfully diagnosed many cases of immune -related difficulties.

Text | Rheumatology Zhu Liang

Review | Chen Guozhong Wu Huaxiang

Editor -in -law | Chen Dan

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