This kind of disease, pain, pain, pain, pain, pain

Author:Earth Knowledge Bureau Time:2022.08.30

It is rumored that there is a magical species called "Golden Snake" in the rivers and lakes. It will specifically choose old and weak people, and circles around these people's waist. People entangled by the golden snake will grow snake -scale blisters, and everyone will be tortured. When the Golden Snake is gradually filled and tightened, these people will die in endless pain.

This damn oppositeness makes me feel suffocated as mammals

(Source: YouTube) ▼

The people call it "snake wrapped waist", or "snake sores". It is said that this disease is not cured, and people entangled by the golden snake are likely to die miserable in a short time.

This disease is called "Herpes Zoster" (Hz), which is caused by chickenpox-zoster virus. It can make Jolin Tsai, who has never been asked to have been vacated for 19 years, to postpone the work. Recently, it has also tortured the Canadian singer Justin Bieber, which caused the latter to cancel the next tour.

Because this virus also infects the facial nervous system

Justin Bieber was paralyzed by this virus for half a face

The eyelids are not listened to (Source: Instagram) ▼

Many people have to have or heard of chickenpox, but they don't know much about herpes. In fact, people have really recognized that shingles have only a history of more than a hundred years.

Golden snake wrapped waist

The record of traditional Chinese medicine about shingles may appear in the Sui Dynasty earlier. In the theory of the Source of the Diseases "," Those who are sore, entangled with the waist. It is considered the earliest record about shingles.

This means that this herpes and trousers are not like the belly on the stomach

(Figure: shutterstock) ▼

However, the opponents believe that only the diseases and symptoms of the disease are described here, and they have not discussed in -depth, and almost no one in later generations use the name of "sore sores".

In the Ming and Qing dynasties, the ancients had a clearer understanding of shingles: "By giving birth to the waist and sores, what is the beads? It is a name of fire, also known as the waistfire ... If you do n’t cure early, entangle your waist and you will be poisoned from the umbilicus, and you will die without eating. " The treatment method includes the use of male yellow, vinegar, wine, and other heat -clearing drugs.

Do not panic with shingles, just three squares of traditional Chinese medicine

Golden sore -the special effects of damage, it is said that it is also used to cure herpes

(Figure: Tuwa Creative) ▼

In the West, the 16th -century Italian doctor Giovanni Filippo first described the characteristics of chickenpox. However, for a long time, people have not accurately distinguished the skin's pegs caused by various reasons, but they are named Great Pox (acne, syphilis), SmallPox (acne, smallpox) and Chickenpox (acne, syphilis), and Chickenpox (acne, Small), Weak chicken acne, chickenpox).

At this time, people did not realize that herpes zoster had any connection with chickenpox. The English name Herpes came from Greek, which means "crawling like a snake".

Sons of shingles has a long history, and the associations of it in East and Western culture are also consistent

It is called "fire belt" in Arabic, and "Little Snake" in Spanish

There is also a common adjective -devil -like pain (Figure: one picture network) ▼

In 1875, Johann Steiner (1833-1876) found that someone was infected with chickenpox infection because of contact with the blisters of acute shingles.

In 1888, Dr. Von Bokay, a doctor in Vienna, found that the children around him who suffered from shingles usually obtained the immunity to chickenpox. Essence

At this time, although the concept of promoting acne vaccines from humans has just passed away

But the method of getting immune to acne has long been deeply rooted in people's hearts

As a doctor, Bokai naturally launched this conclusion

(Planting cattle map: one picture network) ▼

However, because there is no direct evidence support, some people have questioned this hypothesis. Until 1954, the same type of virus was separated from the cell culture of Thomas Huckle Weller (1915-2008) through cell culture, and all talents eventually believed.

In 1954, Thomas was awarded the Nobel Prize in Physiology or Medicine

But not because he discovered the chickenpox-shingles virus

It is to recognize him and colleagues to cultivate spinal ash virus virus

(Figure: Wikipedia ▼ ▼

Chickenpox-shingles virus

The current research believes that the chickenpox-shingles virus belongs to the type 3 human herpes virus and is a DNA virus with a diameter of 150-200nm.

Different from the ceiling virus belonging to the Department of Acne Virus

Chickenpox-shingles virus belong to the herpes virus

(Left slip view more information) ▼

Under normal circumstances, chicken-chip viruses are transmitted through droplets or air, and children, elderly people with low immunity are vulnerable to violations.

When the virus invades the human body, first copy it in the tonsils, and then spreads with the blood circulation; eventually rushes to the skin and forms a rash in the epidermis. Infected to others.

Chickenpox-The history of life with shingles virus will lurk in the nervous system (Source: Nature Review) ▼ ▼

After the chickenpox cure, this virus can also lurk in the neurons of the surrounding autonomic ganglia. When the human body's immunity is low or stimulated by factors such as overwork and drinking, the virus can be activated and increased again, resulting in inflammation and necrosis of nerve festivals that are infringed.

Chickenpox is really too common

So almost the human body is lurking with herpes zoster virus

(Figure: One picture network) ▼

More than half of patients with zostering will go through local nervous system pain. They may feel like being digging the lungs, or they feel like a shock, or they feel that they explode in place. What's more, after some patients were cured, this pain was still followed by shadow, accompanied by life.

Edit Tunan and a chat record of a shingles patient

You can feel the pain of TA from text description

(*Get the patient's consent to post) ▼

At the same time, active viruses can also spread to the skin again along the nerve fiber. Most patients' skin lesions appear on the trunk. Initially manifested as erythema mobilization. (Facial healing faster than other parts).

The process of long blisters will experience from small to large, purulent scabs

(We won't look at it more details, really hurt all at a glance)

(Figure: One picture network) ▼

At the beginning of the 20th century, people generally believed that shingles were not fatal and could be easily cured. However, subsequent studies found that shingles have a fatal threat to people with low immunity. Therefore, active antiviral therapy is required for shingles, and it is necessary to treat neuralgia and complications caused by shingles.

Some of the people of AIDS or low immunity during the onset period

It's very easy to be invaded by this virus, which is comparable to cancer

(Figure: One picture network) ▼

In fact, because shingles are only secondary to the individual who has been infected with chickenpox, the prevention of chickenpox infection is a great choice to prevent shingles.

In 1974, the Japanese scholar Takahashi was clearly separated from a blisa liquid with chickenpox, and the virus was separated. After continuous reproduction of poisoning and reducing poisoning, a chickenpox vaccine species (OKA plant) was established. It is still the wide range of chickenpox vaccines in the world.

Because it can be transmitted by air alone, many children have to have adequate diseases.

Taking advantage of the vaccine before you have to hurry up! (Figure: One picture network) ▼

After the new century, countries around the world have gradually attached great importance to the negative impact of shingles, and they have developed a shingles vaccine.

The currently used vaccines include shingles with herpes herpes to reduce live vaccines (ZVL), as well as reorganized shingles vaccines (RZV), of which RZV has been listed in my country.

RZV, the product is named Shingrix (Xin Anli)

It is currently the only domestic shingles vaccine in China

(Figure: shutterstock) ▼

Positive response

On June 20 this year, the topic of "it is recommended to take parents inoculation as soon as possible with herpes zoster vaccine" quickly appeared on Weibo hot search, and the reading volume exceeded 500 million.

It is estimated that more than 95%of people will suffer from chickenpox when they are childhood or after adulthood, and about one -third of them will have the risk of shingling. Although there is a series of antiviral treatment and other auxiliary treatment, shingles are rarely fatal, but neuralgia, emotional distress, increased medical expenses, and decline in productivity after suffering from shingles influences.

The onset and treatment look a little bad

Students will be affected by their studies, and working people will not go to work like this

(Figure: One picture network) ▼

At present, there are about 1.56 million new shingles of people over the age of 50 in my country. Although the disease is self -limited, the pain and sequelae of the disease will still seriously affect the quality of life. Active response is the right path. According to the current clinical guidelines, the principles of prevention and treatment of shingles in the middle -aged and elderly groups are mainly: active prevention, early diagnosis, and timely treatment.

For decades, the total incidence of shingles has doubled

(Source: MEDSCI) ▼

In addition to exercising the body and improving immunity, inoculation of shingles vaccine is the only means to prevent first -level shingles. According to previous studies, the RZV vaccine currently used in China can provide 97.2%of the protection benefits for people over 50 years old, and can greatly reduce the occurrence of shingles and herpes. In addition, follow -up studies have shown protection effect after 10 years of vaccine vaccine.

Valid for ten years in vaccination

The main thing is that it can be less painful

(Figure: One picture network) ▼

For elderly patients who are diagnosed with shingles, it is particularly important to give a sufficient amount of antiviral drugs in time. At present, antiviral drugs are approved by domestic herpes zoster, including Agelovirville, Pancoswelville, Pancoswell, bromadus. Ding, sodium methampate, etc. At the same time, the patient's condition changes and treatment reactions should be paid closely during the treatment process, and appropriate support treatment should be given.

Compared with young groups, the elderly due to low immunity

Once the disease is onset, it is usually more suffering than young people and children

(Figure: One picture network) ▼

Because most elderly people are currently living alone, many people will not deliberately pay attention to the subtle changes in the body. In addition, the early symptoms of shingles are not typical, and they are often prone to the best time to diagnose and treat. The pressure increased. In view of this, doing a good job of popularization of the whole people and improving the understanding of these diseases are currently urgent.

At present, the proportion of population over 60 years of age in my country has approached 20%, and almost all of them have a latent chickenpox-zoster virus in the human body. As the age grows, the possibility of these viruses will be activated again.

Therefore, it is particularly important to increase the understanding of shingles and complications and timely in vaccination with shingles vaccine in time.

Hello, my parents, good, everyone is really good, everyone is really good

(Figure: One picture network) ▼

references:

[1] China Medical Care International Exchange Promotion Association Dermatology Branch, the China Medical Association Dermatology Branch of Senior Dermatology Research Center. Schilogy vaccine prevention expert consensus. Chinese Medical Journal. 2022. 102 (08): 538- 543.

[2] Lal H, Cunningham Al, Godeaux O, et al. Effical of an Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults. N English. 2015.372 (22): 2087-96.

[3] Tricco AC, Zarin W, Cardoso R, et al. Efficacy, effectiveness, and safety of herpes zoster vaccines in adults aged 50 and older: systematic review and network meta-analysis. BMJ. 2018. 363: k4029.

[4] Weinberg JM. Herpes Zoster: Epidemiology, Natural History, and Common Complications. J am Acad Dermatol. 2007. 57: S130-5.

[5] Gao Ruidi, Yang Huilan, Liu Zhongrong, Fan Jianyong. Vicerals-Zospellings virus research progress. China Ma Feng Skin Disease Magazine. 2014.30 (04): 216-219.

[6] Harbecke R, Cohen Ji, Oxman Mn. Herpes Zoster Vaccines. J infect Dis. 2021. 224 (12 SUPPL 2): S429-S442.

[7] Schmader K. Herpes Zoster. Ann Intern Med. 2018. 169 (3): ITC19-ITC31.

[8] Wrensch M, Weinberg A, Wiencke J, et al. History of chickenpox and shingles and prevalence of antibodies to varicella-zoster virus and three other herpesviruses among adults with glioma and controls. Am J Epidemiol. 2005. 161(10) : 929-38.

[9] Xiong Mei, Luo Zhicheng. Research on the research of zoster epidemic disease. Practical clinical pharmaceutical magazine. 2022. 26 (07): 144-148.

[10] Gershon Aa, Breuer J, Cohen Ji, et al. Varicella Zoster Virus information. Nat Rev Dis Primers. 2015.1: 15016.

[11] Rosamilia ll. Herpes Zoster Presentation, Management, and Prevention: A Modern Case-Based Review. AM J Clin Dermatol. 2020. 21 (1): 97-107.

[12] Wang Yizheng, Cheng Hongbin, Wu Jingping, still quiet, Zhao Peixuan. Singering in the sources of ancient literature with herpes zoster. Frontiers of Medicine. 2016. 6 (27): 315-316.Varicella-Zoster Virus Infection. Viruses. 2018. 10 (11).

[14] There is a kind of pain called "shingles", as soon as possible to take parents to vaccine, Guangming.com, 2022-06-20 14:58 Published.

[15] Wu Shutian, Wu Minfeng, Huang Jianhua, Wang Hongwei. Special clinical manifestations and prevention of aged shingles. Elderly medicine and health care. 2021. 27 (03): 661-664.

*The content of this article is provided for the author, which does not represent the position of the Earth Investment Bureau

Cover: shutterstock

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